Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes S100A1
  • Mouse genes S100a1
  • Rat genes S100a1
  • Zfish genes s100a1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set S100a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	S100A1	IPI	UniProtKB:P16615	Human	PMID:12804600
Molecular Function	GO:0005509	calcium ion binding	S100a1	IDA		Rat	PMID:16169012|RGD:7205632
Molecular Function	GO:0048306	calcium-dependent protein binding	S100a1	IPI	RGD:3797	Rat	PMID:10567243|RGD:7205635
Molecular Function	GO:0048306	calcium-dependent protein binding	S100a1	IPI	RGD:3798	Rat	PMID:10567243|RGD:7205635
Molecular Function	GO:0042802	identical protein binding	S100A1	IPI	UniProtKB:P23297	Human	PMID:10913138
Molecular Function	GO:0042802	identical protein binding	S100A1	IPI	UniProtKB:P23297	Human	PMID:15171681
Molecular Function	GO:0042802	identical protein binding	S100A1	IPI	UniProtKB:P23297	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	S100A1	IPI	UniProtKB:P23297	Human	PMID:21296671
Molecular Function	GO:0042802	identical protein binding	S100A1	IPI	UniProtKB:P23297	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	S100A1	IPI	UniProtKB:P23297	Human	PMID:32296183
Molecular Function	GO:0042802	identical protein binding	S100a1	IPI	RGD:3614	Rat	PMID:16169012|RGD:7205632
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P04271	Human	PMID:10913138
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P23297	Human	PMID:10913138
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P25815	Human	PMID:15171681
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P04271	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P25815	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P26447	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P04637	Human	PMID:20591429
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:Q00987	Human	PMID:20591429
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P04271	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P04271	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P25815	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P29034	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:Q9H8W4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P04271	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P04271	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P29034	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:O15151	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P04637	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P32418	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P35579	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P52907	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P04271	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P25815	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P26447	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P29034	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P33764	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:Q00994	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:Q8WXG8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:P04271	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100A1	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	S100a1	IPI	UniProtKB:P07091	Mouse	MGI:MGI:3763311|PMID:10869553
Molecular Function	GO:0005515	protein binding	S100a1	IPI	UniProtKB:P07900	Rat	PMID:14638689|RGD:8554444
Molecular Function	GO:0005515	protein binding	S100a1	IPI	UniProtKB:P26882	Rat	PMID:14638689|RGD:8554444
Molecular Function	GO:0005515	protein binding	S100a1	IPI	UniProtKB:Q02790	Rat	PMID:14638689|RGD:8554444
Molecular Function	GO:0005515	protein binding	S100a1	IPI	UniProtKB:Q63495	Rat	PMID:19910580|RGD:2325647
Molecular Function	GO:0005515	protein binding	S100a1	IPI	UniProtKB:P26882	Rat	PMID:20188096|RGD:8554089
Molecular Function	GO:0005515	protein binding	S100a1	IPI	UniProtKB:Q02790	Rat	PMID:20188096|RGD:8554089
Molecular Function	GO:0042803	protein homodimerization activity	S100A1	IDA		Human	PMID:10913138
Molecular Function	GO:0044548	S100 protein binding	S100A1	IPI	UniProtKB:P04271	Human	PMID:10913138
Molecular Function	GO:0044548	S100 protein binding	S100A1	IPI	UniProtKB:P23297	Human	PMID:10913138
Cellular Component	GO:0031672	A band	S100a1	IDA		Rat	PMID:11156445|RGD:7205634
Cellular Component	GO:0005737	cytoplasm	S100a1	IDA		Rat	PMID:19657060|RGD:7205633
Cellular Component	GO:0005829	cytosol	S100A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	S100A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031674	I band	S100a1	IDA		Rat	PMID:11156445|RGD:7205634
Cellular Component	GO:0031430	M band	S100a1	IDA		Rat	PMID:11156445|RGD:7205634
Cellular Component	GO:0043005	neuron projection	S100a1	IDA		Rat	PMID:19657060|RGD:7205633
Cellular Component	GO:0005654	nucleoplasm	S100A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	S100A1	IDA		Human	PMID:12118070
Cellular Component	GO:0016529	sarcoplasmic reticulum	S100A1	IDA		Human	PMID:12804600
Cellular Component	GO:0016529	sarcoplasmic reticulum	S100a1	IDA		Mouse	PMID:12804600
Cellular Component	GO:0030018	Z disc	S100a1	IDA		Rat	PMID:11156445|RGD:7205634
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	S100a1	IMP		Rat	PMID:12619862|RGD:735233
Biological Process	GO:0051000	positive regulation of nitric-oxide synthase activity	S100A1	IDA		Human	PMID:24244340
Biological Process	GO:1903672	positive regulation of sprouting angiogenesis	S100A1	IDA		Human	PMID:24244340
Biological Process	GO:1901387	positive regulation of voltage-gated calcium channel activity	S100a1	IDA		Rat	PMID:19657060|RGD:7205633
Biological Process	GO:0021762	substantia nigra development	S100A1	HEP		Human	PMID:22926577

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern