Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes S100A7,S100A7A,S100A7L2
  • Mouse genes S100a7a
  • Rat genes S100a7a
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set S100a7a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	S100A7	IDA		Human	PMID:8077703
Molecular Function	GO:0042056	chemoattractant activity	S100a7a	IDA		Mouse	PMID:21148126
Molecular Function	GO:0005515	protein binding	S100A7	IPI	UniProtKB:Q96S59	Human	PMID:12421467
Molecular Function	GO:0005515	protein binding	S100A7	IPI	UniProtKB:Q01469	Human	PMID:12839573
Molecular Function	GO:0005515	protein binding	S100A7	IPI	UniProtKB:Q5SY68	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100A7	IPI	UniProtKB:Q5SYC1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100A7L2	IPI	UniProtKB:P31151	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100A7L2	IPI	UniProtKB:Q86SG5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100A7L2	IPI	UniProtKB:Q9NRY6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100A7A	IPI	UniProtKB:Q5SY68	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100A7A	IPI	UniProtKB:Q5SYC1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100a7a	IPI	PR:Q62151	Mouse	PMID:21148126
Molecular Function	GO:0043621	protein self-association	S100A7A	IDA		Human	PMID:21148126
Molecular Function	GO:0050786	RAGE receptor binding	S100A7	IPI	UniProtKB:Q62151	Human	PMID:18606705
Molecular Function	GO:0140486	zinc ion sequestering activity	S100A7	IDA		Human	PMID:15568027
Cellular Component	GO:0062023	collagen-containing extracellular matrix	S100A7	HDA		Human	PMID:27068509
Cellular Component	GO:0005737	cytoplasm	S100A7	IDA		Human	PMID:10595935
Cellular Component	GO:0005829	cytosol	S100A7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	S100A7	IDA		Human	PMID:12839573
Cellular Component	GO:0005829	cytosol	S100A7A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	S100A7	IDA		Human	PMID:12839573
Cellular Component	GO:0005576	extracellular region	S100A7	IDA		Human	PMID:11782356
Cellular Component	GO:0005576	extracellular region	S100A7	IDA		Human	PMID:15568027
Cellular Component	GO:0005615	extracellular space	S100A7	IDA		Human	PMID:21805676
Cellular Component	GO:0005615	extracellular space	S100A7L2	IDA		Human	PMID:21805676
Cellular Component	GO:0005615	extracellular space	S100a7a	IDA		Mouse	PMID:21148126
Cellular Component	GO:0005634	nucleus	S100A7	IDA		Human	PMID:10595935
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	S100A7	IMP		Human	PMID:15568027
Biological Process	GO:0001816	cytokine production	S100a7a	IDA		Mouse	PMID:21148126
Biological Process	GO:0006954	inflammatory response	S100a7a	IGI	MGI:MGI:893592	Mouse	PMID:21148126
Biological Process	GO:0006954	inflammatory response	S100a7a	IGI	MGI:MGI:104798	Mouse	PMID:21148126
Biological Process	GO:0006954	inflammatory response	S100a7a	IDA		Mouse	PMID:21148126
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	S100A7	IDA		Human	PMID:18606705
Biological Process	GO:0071624	positive regulation of granulocyte chemotaxis	S100A7	IDA		Human	PMID:18606705
Biological Process	GO:0090026	positive regulation of monocyte chemotaxis	S100A7	IDA		Human	PMID:18606705
Biological Process	GO:0010820	positive regulation of T cell chemotaxis	S100A7	IDA		Human	PMID:18606705
Biological Process	GO:0032496	response to lipopolysaccharide	S100A7	IEP		Human	PMID:17625598
Biological Process	GO:0000302	response to reactive oxygen species	S100A7	IDA		Human	PMID:16082188

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern