Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes S100A9
  • Mouse genes S100a9
  • Rat genes S100a9
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set S100a9

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	S100A9	IPI	UniProtKB:P32121	Human	PMID:17620599
Molecular Function	GO:0005515	protein binding	S100A9	IPI	UniProtKB:P49407	Human	PMID:17620599
Molecular Function	GO:0005515	protein binding	S100A9	IPI	UniProtKB:P05109	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	S100A9	IPI	UniProtKB:P20138	Human	PMID:24216507
Molecular Function	GO:0005515	protein binding	S100A9	IPI	UniProtKB:P05109	Human	PMID:25417112
Molecular Function	GO:0005515	protein binding	S100A9	IPI	UniProtKB:P04271	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100A9	IPI	UniProtKB:P43355	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100A9	IPI	UniProtKB:P43357	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100A9	IPI	UniProtKB:P43360	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	S100A9	IPI	UniProtKB:P05109	Human	PMID:9867828
Cellular Component	GO:0062023	collagen-containing extracellular matrix	S100A9	HDA		Human	PMID:23979707
Cellular Component	GO:0062023	collagen-containing extracellular matrix	S100A9	HDA		Human	PMID:28344315
Cellular Component	GO:0062023	collagen-containing extracellular matrix	S100A9	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	S100A9	HDA		Human	PMID:28675934
Cellular Component	GO:0001533	cornified envelope	S100a9	IDA		Mouse	PMID:26644517
Cellular Component	GO:0005737	cytoplasm	S100A9	IDA		Human	PMID:12874352
Cellular Component	GO:0070062	extracellular exosome	S100A9	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	S100A9	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	S100A9	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	S100A9	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	S100A9	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	S100A9	IDA		Human	PMID:21805676
Cellular Component	GO:0005615	extracellular space	S100A9	HDA		Human	PMID:22664934
Cellular Component	GO:0005615	extracellular space	S100A9	HDA		Human	PMID:23580065
Cellular Component	GO:0005615	extracellular space	S100a9	IDA		Rat	PMID:15221771|RGD:2316912
Cellular Component	GO:0005634	nucleus	S100A9	HDA		Human	PMID:21630459
Biological Process	GO:0030036	actin cytoskeleton organization	S100a9	IMP	MGI:MGI:2450165	Mouse	PMID:12529407
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	S100A9	IDA		Human	PMID:19935772
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	S100A9	IDA		Human	PMID:12874352
Biological Process	GO:0014002	astrocyte development	S100a9	IGI	MGI:MGI:88244	Mouse	PMID:22577135
Biological Process	GO:0035425	autocrine signaling	S100a9	IGI	UniProtKB:Q4FZY1	Rat	PMID:27312849|RGD:13838801
Biological Process	GO:0006914	autophagy	S100A9	IDA		Human	PMID:19935772
Biological Process	GO:0002544	chronic inflammatory response	S100a9	IEP		Rat	PMID:8343166|RGD:633930
Biological Process	GO:0030595	leukocyte chemotaxis	S100a9	IMP	MGI:MGI:2450165	Mouse	PMID:12529407
Biological Process	GO:0002523	leukocyte migration involved in inflammatory response	S100A9	IDA		Human	PMID:12626582
Biological Process	GO:0035821	modulation of process of another organism	S100A9	IDA		Human	PMID:12874352
Biological Process	GO:0070488	neutrophil aggregation	S100A9	IDA		Human	PMID:12626582
Biological Process	GO:0030593	neutrophil chemotaxis	S100A9	IDA		Human	PMID:12626582
Biological Process	GO:0002790	peptide secretion	S100a9	IMP		Mouse	PMID:18820689
Biological Process	GO:0002790	peptide secretion	S100a9	IDA		Mouse	PMID:18820689
Biological Process	GO:0018119	peptidyl-cysteine S-nitrosylation	S100a9	IMP		Mouse	MGI:MGI:5621255|PMID:25417112
Biological Process	GO:0035606	peptidyl-cysteine S-trans-nitrosylation	S100A9	IDA		Human	PMID:25417112
Biological Process	GO:0030194	positive regulation of blood coagulation	S100a9	IMP		Mouse	MGI:MGI:5582990|PMID:24691441
Biological Process	GO:0050729	positive regulation of inflammatory response	S100A9	IDA		Human	PMID:12626582
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	S100A9	IDA		Human	PMID:19935772
Biological Process	GO:0010976	positive regulation of neuron projection development	S100a9	IDA		Rat	PMID:23825416|RGD:8655547
Biological Process	GO:0002793	positive regulation of peptide secretion	S100a9	IDA		Mouse	PMID:18820689
Biological Process	GO:0002793	positive regulation of peptide secretion	S100a9	IMP		Mouse	PMID:18820689
Biological Process	GO:0045113	regulation of integrin biosynthetic process	S100a9	IMP	MGI:MGI:2450165	Mouse	PMID:12529407
Biological Process	GO:0006417	regulation of translation	S100a9	IMP		Mouse	MGI:MGI:5621255|PMID:25417112
Biological Process	GO:0045471	response to ethanol	S100a9	IEP		Rat	PMID:17207109|RGD:2316908
Biological Process	GO:0032496	response to lipopolysaccharide	S100a9	IEP		Rat	PMID:17207109|RGD:2316908
Biological Process	GO:0010043	response to zinc ion	S100a9	IEP		Rat	PMID:19111725|RGD:2316905

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern