Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SAA1,SAA2
  • Mouse genes Saa1
  • Rat genes
  • Zfish genes saa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Saa1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001664	G protein-coupled receptor binding	SAA1	IDA		Human	PMID:9892621
Molecular Function	GO:0005515	protein binding	SAA2	IPI	UniProtKB:Q9UHD4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Saa1	IPI	PR:P19137	Mouse	PMID:8995276
Cellular Component	GO:0005881	cytoplasmic microtubule	SAA1	IDA		Human	PMID:22131810
Cellular Component	GO:0070062	extracellular exosome	SAA1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	SAA1	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	SAA2	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	Saa1	IDA		Mouse	PMID:9300780
Biological Process	GO:0048469	cell maturation	saa	IMP	ZFIN:ZDB-GENO-200723-11	Zfish	PMID:30845179
Biological Process	GO:0008203	cholesterol metabolic process	Saa1	IDA		Mouse	PMID:9300780
Biological Process	GO:0048247	lymphocyte chemotaxis	SAA1	IDA		Human	PMID:7636186
Biological Process	GO:0048246	macrophage chemotaxis	SAA1	IDA		Human	PMID:7561109
Biological Process	GO:0030593	neutrophil chemotaxis	saa	IMP	ZFIN:ZDB-GENO-200723-11	Zfish	PMID:30845179
Biological Process	GO:0030593	neutrophil chemotaxis	saa	IMP	ZFIN:ZDB-GENO-200723-21	Zfish	PMID:30845179
Biological Process	GO:0030593	neutrophil chemotaxis	saa	IMP	ZFIN:ZDB-GENO-200723-14	Zfish	PMID:30845179
Biological Process	GO:0001780	neutrophil homeostasis	saa	IMP	ZFIN:ZDB-GENO-200723-11	Zfish	PMID:30845179
Biological Process	GO:1990266	neutrophil migration	saa	IMP	ZFIN:ZDB-MRPHLNO-150826-1	Zfish	PMID:24373309
Biological Process	GO:0070944	neutrophil-mediated killing of bacterium	saa	IMP	ZFIN:ZDB-GENO-200723-11	Zfish	PMID:30845179
Biological Process	GO:0070944	neutrophil-mediated killing of bacterium	saa	IMP	ZFIN:ZDB-GENO-200723-14	Zfish	PMID:30845179
Biological Process	GO:0070944	neutrophil-mediated killing of bacterium	saa	IMP	ZFIN:ZDB-GENO-200723-21	Zfish	PMID:30845179
Biological Process	GO:0045785	positive regulation of cell adhesion	SAA1	IDA		Human	PMID:11830469
Biological Process	GO:0045785	positive regulation of cell adhesion	SAA1	IDA		Human	PMID:9252455
Biological Process	GO:0001819	positive regulation of cytokine production	SAA1	IDA		Human	PMID:12857601
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	SAA1	IDA		Human	PMID:9892621
Biological Process	GO:0009617	response to bacterium	Saa1	IEP		Mouse	PMID:23012479
Biological Process	GO:0009617	response to bacterium	saa	IDA		Zfish	PMID:16630661
Biological Process	GO:0009617	response to bacterium	saa	IDA		Zfish	PMID:17055441

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern