Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SAE1
  • Mouse genes Sae1
  • Rat genes Sae1
  • Zfish genes sae1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sae1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043008	ATP-dependent protein binding	SAE1	IDA		Human	PMID:10187858
Molecular Function	GO:0005515	protein binding	SAE1	IPI	UniProtKB:Q9UBT2	Human	PMID:10187858
Molecular Function	GO:0005515	protein binding	SAE1	IPI	UniProtKB:Q9UBT2	Human	PMID:15660128
Molecular Function	GO:0005515	protein binding	SAE1	IPI	UniProtKB:Q9UBT2	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	SAE1	IPI	UniProtKB:Q9UBT2	Human	PMID:20164921
Molecular Function	GO:0005515	protein binding	SAE1	IPI	UniProtKB:Q9UBT2	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	SAE1	IPI	UniProtKB:Q9UBT2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SAE1	IPI	UniProtKB:Q9UBT2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SAE1	IPI	UniProtKB:O43186	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SAE1	IPI	UniProtKB:P26367	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SAE1	IPI	UniProtKB:Q02548	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SAE1	IPI	UniProtKB:Q06710	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SAE1	IPI	UniProtKB:Q13952-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SAE1	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0046982	protein heterodimerization activity	SAE1	IPI	UniProtKB:Q9UBT2	Human	PMID:20164921
Molecular Function	GO:0044388	small protein activating enzyme binding	SAE1	IPI	UniProtKB:Q9UBT2	Human	PMID:15660128
Molecular Function	GO:0019948	SUMO activating enzyme activity	SAE1	IDA		Human	PMID:10187858
Molecular Function	GO:0019948	SUMO activating enzyme activity	SAE1	IDA		Human	PMID:20164921
Cellular Component	GO:0005654	nucleoplasm	SAE1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SAE1	HDA		Human	PMID:16791210
Cellular Component	GO:0031510	SUMO activating enzyme complex	SAE1	IDA		Human	PMID:10187858
Cellular Component	GO:0031510	SUMO activating enzyme complex	SAE1	IDA		Human	PMID:15660128
Cellular Component	GO:0031510	SUMO activating enzyme complex	SAE1	IDA		Human	PMID:20164921
Biological Process	GO:0060216	definitive hemopoiesis	sae1	IMP	ZFIN:ZDB-GENO-121220-2	Zfish	PMID:23132242
Biological Process	GO:0060216	definitive hemopoiesis	sae1	IMP	ZFIN:ZDB-GENO-121220-2	Zfish	PMID:25757417
Biological Process	GO:0061484	hematopoietic stem cell homeostasis	sae1	IMP	ZFIN:ZDB-GENO-121220-2	Zfish	PMID:23132242
Biological Process	GO:0033235	positive regulation of protein sumoylation	SAE1	IDA		Human	PMID:10187858
Biological Process	GO:1903955	positive regulation of protein targeting to mitochondrion	SAE1	HMP		Human	PMID:24270810
Biological Process	GO:0016925	protein sumoylation	SAE1	IDA		Human	PMID:15660128
Biological Process	GO:0016925	protein sumoylation	SAE1	IDA		Human	PMID:20164921
Biological Process	GO:0016925	protein sumoylation	SAE1	IMP		Human	PMID:21968017
Biological Process	GO:0016925	protein sumoylation	sae1	IMP	ZFIN:ZDB-GENO-121220-2	Zfish	PMID:23132242

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern