Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SAFB
  • Mouse genes Safb
  • Rat genes Safb
  • Zfish genes safb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Safb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Safb	IDA		Mouse	MGI:MGI:5284748|PMID:19403048
Molecular Function	GO:0005515	protein binding	SAFB	IPI	UniProtKB:Q14151	Human	PMID:12660241
Molecular Function	GO:0005515	protein binding	SAFB	IPI	UniProtKB:Q9JKL7	Human	PMID:14559993
Molecular Function	GO:0005515	protein binding	SAFB	IPI	UniProtKB:Q91V33	Human	PMID:15345239
Molecular Function	GO:0005515	protein binding	SAFB	IPI	UniProtKB:P84586	Human	PMID:19282290
Molecular Function	GO:0005515	protein binding	SAFB	IPI	UniProtKB:Q96SB4-2	Human	PMID:19674106
Molecular Function	GO:0005515	protein binding	SAFB	IPI	UniProtKB:Q96SB4-3	Human	PMID:19674106
Molecular Function	GO:0005515	protein binding	SAFB	IPI	UniProtKB:Q9GZQ8	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	SAFB	IPI	UniProtKB:P04637	Human	PMID:21130767
Molecular Function	GO:0005515	protein binding	SAFB	IPI	UniProtKB:Q9GZQ8	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	SAFB	IPI	UniProtKB:O75132	Human	PMID:22693546
Molecular Function	GO:0005515	protein binding	SAFB	IPI	UniProtKB:P35637	Human	PMID:27731383
Molecular Function	GO:0005515	protein binding	Safb	IPI	UniProtKB:Q91VM5	Mouse	MGI:MGI:5284748|PMID:19403048
Molecular Function	GO:0005515	protein binding	Safb	IPI	PR:Q61658	Mouse	PMID:17931718
Molecular Function	GO:0005515	protein binding	Safb	IPI	RGD:621706	Rat	PMID:10564280|RGD:634512
Molecular Function	GO:0005515	protein binding	Safb	IPI	UniProtKB:Q96SB4	Rat	PMID:11509566|RGD:8554218
Molecular Function	GO:0005515	protein binding	Safb	IPI	RGD:1565256	Rat	PMID:19282290|RGD:2316827
Molecular Function	GO:0005515	protein binding	Safb	IPI	RGD:1309495	Rat	PMID:9671816|RGD:634000
Molecular Function	GO:0003723	RNA binding	SAFB	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	SAFB	HDA		Human	PMID:22681889
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Safb	IDA		Mouse	MGI:MGI:5284748|PMID:19403048
Molecular Function	GO:0043565	sequence-specific DNA binding	Safb	IDA		Rat	PMID:9671816|RGD:634000
Cellular Component	GO:0030496	midbody	SAFB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SAFB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SAFB	IDA		Human	PMID:22693546
Cellular Component	GO:0005634	nucleus	Safb	IDA		Rat	PMID:9671816|RGD:634000
Biological Process	GO:0042445	hormone metabolic process	Safb	IMP	MGI:MGI:3577076	Mouse	PMID:15798188
Biological Process	GO:0030520	intracellular estrogen receptor signaling pathway	Safb	IMP	MGI:MGI:3577076	Mouse	PMID:15798188
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Safb	IMP		Mouse	MGI:MGI:5284748|PMID:19403048
Biological Process	GO:0040008	regulation of growth	Safb	IMP	MGI:MGI:3577076	Mouse	PMID:15798188
Biological Process	GO:0050684	regulation of mRNA processing	Safb	IDA		Rat	PMID:9671816|RGD:634000
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Safb	IDA		Rat	PMID:9671816|RGD:634000

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern