Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SALL4
  • Mouse genes Sall4
  • Rat genes Sall4
  • Zfish genes sall4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sall4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	sall4	IDA		Zfish	PMID:24286030
Molecular Function	GO:0005515	protein binding	SALL4	IPI	UniProtKB:Q5T5X7	Human	PMID:21914818
Molecular Function	GO:0005515	protein binding	Sall4	IPI	UniProtKB:Q8BVE8-2	Mouse	MGI:MGI:3850584|PMID:19483677
Molecular Function	GO:0005515	protein binding	Sall4	IPI	UniProtKB:O70230|UniProtKB:Q7TSZ8|UniProtKB:Q9R190	Mouse	MGI:MGI:5320277|PMID:20362541
Molecular Function	GO:0005515	protein binding	Sall4	IPI	UniProtKB:Q9UHY1	Mouse	MGI:MGI:5426079|PMID:22510880
Molecular Function	GO:0005515	protein binding	Sall4	IPI	UniProtKB:Q61539|UniProtKB:Q62315	Mouse	MGI:MGI:5887185|PMID:26523946
Molecular Function	GO:0005515	protein binding	Sall4	IPI	PR:O09106	Mouse	PMID:19796622
Molecular Function	GO:0005515	protein binding	Sall4	IPI	PR:P70326	Mouse	PMID:16380715
Molecular Function	GO:0005515	protein binding	Sall4	IPI	PR:P70325	Mouse	PMID:16380715
Molecular Function	GO:0008134	transcription factor binding	Sall4	IPI	UniProtKB:E9Q3T6	Mouse	MGI:MGI:5887185|PMID:26523946
Cellular Component	GO:0000792	heterochromatin	Sall4	IDA		Mouse	PMID:17295837
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SALL4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SALL4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Sall4	IDA		Mouse	PMID:19796622
Cellular Component	GO:0032991	protein-containing complex	Sall4	IDA		Mouse	PMID:19796622
Biological Process	GO:0030326	embryonic limb morphogenesis	Sall4	IGI	MGI:MGI:102541	Mouse	PMID:16380715
Biological Process	GO:0030326	embryonic limb morphogenesis	Sall4	IMP	MGI:MGI:3587949	Mouse	PMID:16380715
Biological Process	GO:0035118	embryonic pectoral fin morphogenesis	sall4	IMP	ZFIN:ZDB-MRPHLNO-060328-1	Zfish	PMID:16501170
Biological Process	GO:0007507	heart development	Sall4	IMP	MGI:MGI:3587949	Mouse	PMID:16380715
Biological Process	GO:0001701	in utero embryonic development	Sall4	IMP	MGI:MGI:3692447	Mouse	PMID:17060609
Biological Process	GO:0001833	inner cell mass cell proliferation	Sall4	IMP	MGI:MGI:3699175	Mouse	PMID:16790473
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Sall4	IGI	MGI:MGI:102541	Mouse	PMID:16380715
Biological Process	GO:0001843	neural tube closure	Sall4	IGI	MGI:MGI:1889585	Mouse	PMID:16790473
Biological Process	GO:0001843	neural tube closure	Sall4	IMP	MGI:MGI:3699175	Mouse	PMID:16790473
Biological Process	GO:0021915	neural tube development	Sall4	IGI	MGI:MGI:1354373	Mouse	PMID:18818376
Biological Process	GO:0021915	neural tube development	Sall4	IGI	MGI:MGI:1889585	Mouse	PMID:18818376
Biological Process	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway	sall4	IMP	ZFIN:ZDB-MRPHLNO-060328-1	Zfish	PMID:16501170
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sall4	IGI	MGI:MGI:102541	Mouse	PMID:16380715
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sall4	IDA		Mouse	PMID:16380715
Biological Process	GO:0035019	somatic stem cell population maintenance	Sall4	IMP		Mouse	PMID:20720539
Biological Process	GO:0009888	tissue development	Sall4	IMP	MGI:MGI:3692447	Mouse	PMID:17060609
Biological Process	GO:0003281	ventricular septum development	Sall4	IMP	MGI:MGI:3699175	Mouse	PMID:16790473
Biological Process	GO:0003281	ventricular septum development	Sall4	IGI	MGI:MGI:1889585	Mouse	PMID:16790473

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern