Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SAMM50
  • Mouse genes Samm50
  • Rat genes Samm50
  • Zfish genes samm50,samm50l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Samm50

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SAMM50	IPI	UniProtKB:Q9NX63	Human	PMID:21081504
Molecular Function	GO:0005515	protein binding	SAMM50	IPI	UniProtKB:Q9NX63	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SAMM50	IPI	UniProtKB:O00429	Human	PMID:27059175
Molecular Function	GO:0005515	protein binding	SAMM50	IPI	UniProtKB:O95140	Human	PMID:27059175
Molecular Function	GO:0005515	protein binding	SAMM50	IPI	UniProtKB:Q9NVT9	Human	PMID:31644573
Molecular Function	GO:0005515	protein binding	SAMM50	IPI	UniProtKB:Q9BRQ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SAMM50	IPI	UniProtKB:Q9NX63	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Samm50	IPI	UniProtKB:Q9CRB9	Mouse	MGI:MGI:5009773|PMID:21081504
Cellular Component	GO:0070062	extracellular exosome	SAMM50	HDA		Human	PMID:19056867
Cellular Component	GO:0016020	membrane	SAMM50	IDA		Human	PMID:15644312
Cellular Component	GO:0140275	MIB complex	SAMM50	HDA		Human	PMID:26477565
Cellular Component	GO:0005743	mitochondrial inner membrane	Samm50	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005741	mitochondrial outer membrane	SAMM50	IDA		Human	PMID:15644312
Cellular Component	GO:0005739	mitochondrion	SAMM50	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	SAMM50	IDA		Human	PMID:15644312
Cellular Component	GO:0005739	mitochondrion	SAMM50	HDA		Human	PMID:20833797
Cellular Component	GO:0005739	mitochondrion	SAMM50	IDA		Human	PMID:25781180
Cellular Component	GO:0005739	mitochondrion	Samm50	HDA		Mouse	PMID:18614015
Cellular Component	GO:0001401	SAM complex	SAMM50	IPI		Human	PMID:17510655
Cellular Component	GO:0001401	SAM complex	SAMM50	IMP		Human	PMID:15644312
Cellular Component	GO:0001401	SAM complex	SAMM50	HDA		Human	PMID:26477565
Biological Process	GO:0042407	cristae formation	SAMM50	IMP		Human	PMID:22252321
Biological Process	GO:0042407	cristae formation	SAMM50	IMP		Human	PMID:25781180
Biological Process	GO:0001889	liver development	samm50	IMP	ZFIN:ZDB-MRPHLNO-131120-12	Zfish	PMID:23813869
Biological Process	GO:0033108	mitochondrial respiratory chain complex assembly	SAMM50	IMP		Human	PMID:22252321
Biological Process	GO:0045040	protein insertion into mitochondrial outer membrane	SAMM50	IDA		Human	PMID:15644312

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern