Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SAP130
  • Mouse genes Sap130
  • Rat genes Sap130
  • Zfish genes sap130a,sap130b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sap130

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Sap130	IPI	UniProtKB:Q9R0Q8	Mouse	MGI:MGI:3817341|PMID:18776906
Cellular Component	GO:0016607	nuclear speck	SAP130	IDA		Human	GO_REF:0000052
Biological Process	GO:0003231	cardiac ventricle development	sap130a	IMP	ZFIN:ZDB-GENO-170815-2	Zfish	PMID:28530678
Biological Process	GO:0003231	cardiac ventricle development	sap130a	IMP	ZFIN:ZDB-MRPHLNO-170809-1	Zfish	PMID:28530678
Biological Process	GO:0021508	floor plate formation	sap130a	IGI	ZFIN:ZDB-MRPHLNO-151116-6,ZFIN:ZDB-MRPHLNO-151116-7	Zfish	PMID:25533962
Biological Process	GO:0021508	floor plate formation	sap130b	IGI	ZFIN:ZDB-MRPHLNO-151116-6,ZFIN:ZDB-MRPHLNO-151116-7	Zfish	PMID:25533962
Biological Process	GO:0008345	larval locomotory behavior	sap130a	IGI	ZFIN:ZDB-MRPHLNO-151116-6,ZFIN:ZDB-MRPHLNO-151116-7	Zfish	PMID:25533962
Biological Process	GO:0008345	larval locomotory behavior	sap130b	IGI	ZFIN:ZDB-MRPHLNO-151116-6,ZFIN:ZDB-MRPHLNO-151116-7	Zfish	PMID:25533962
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SAP130	IMP		Human	PMID:22783022
Biological Process	GO:0001966	thigmotaxis	sap130a	IGI	ZFIN:ZDB-MRPHLNO-151116-6,ZFIN:ZDB-MRPHLNO-151116-7	Zfish	PMID:25533962
Biological Process	GO:0001966	thigmotaxis	sap130b	IGI	ZFIN:ZDB-MRPHLNO-151116-6,ZFIN:ZDB-MRPHLNO-151116-7	Zfish	PMID:25533962

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern