Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SCAF8
  • Mouse genes Scaf8
  • Rat genes Scaf8
  • Zfish genes scaf8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Scaf8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SCAF8	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SCAF8	IPI	UniProtKB:Q08379	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SCAF8	IPI	UniProtKB:O75420	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCAF8	IPI	UniProtKB:Q8IYF3-3	Human	PMID:32296183
Molecular Function	GO:0019904	protein domain specific binding	Scaf8	IMP		Rat	PMID:8692929|RGD:1299392
Molecular Function	GO:0003723	RNA binding	SCAF8	IDA		Human	PMID:31104839
Molecular Function	GO:0070063	RNA polymerase binding	Scaf8	IPI	UniProtKB:P08775	Rat	PMID:9528809|RGD:8554489
Molecular Function	GO:0043175	RNA polymerase core enzyme binding	SCAF8	IPI	UniProtKB:P24928	Human	PMID:18550522
Molecular Function	GO:1990269	RNA polymerase II C-terminal domain phosphoserine binding	SCAF8	IDA		Human	PMID:31104839
Cellular Component	GO:0016363	nuclear matrix	Scaf8	IDA		Rat	PMID:9528809|RGD:8554489
Cellular Component	GO:0005654	nucleoplasm	SCAF8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SCAF8	IDA		Human	PMID:31104839
Biological Process	GO:0006397	mRNA processing	Scaf8	IMP		Rat	PMID:8692929|RGD:1299392
Biological Process	GO:2000805	negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled	SCAF8	IDA		Human	PMID:31104839
Biological Process	GO:0032786	positive regulation of DNA-templated transcription, elongation	SCAF8	IDA		Human	PMID:31104839
Biological Process	GO:0006366	transcription by RNA polymerase II	Scaf8	IMP		Rat	PMID:8692929|RGD:1299392

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern