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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Scarb2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Scarb2
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0038024cargo receptor activitySCARB2IMPHumanPMID:18022370
Molecular FunctionGO:0038024cargo receptor activityScarb2IMPMouseMGI:MGI:3773765|PMID:18022370
Molecular FunctionGO:0015485cholesterol bindingScarb2IDAMouseMGI:MGI:6112073|PMID:29199275
Molecular FunctionGO:0019899enzyme bindingSCARB2IPIUniProtKB:P17439HumanPMID:18022370
Molecular FunctionGO:0019899enzyme bindingSCARB2IPIUniProtKB:P04062HumanPMID:25202012
Molecular FunctionGO:0019899enzyme bindingScarb2IPIUniProtKB:P17439MouseMGI:MGI:3773765|PMID:18022370
Molecular FunctionGO:0031210phosphatidylcholine bindingScarb2IDAMouseMGI:MGI:6112073|PMID:29199275
Molecular FunctionGO:0001786phosphatidylserine bindingScarb2IDAMouseMGI:MGI:6112073|PMID:29199275
Molecular FunctionGO:0005515protein bindingSCARB2IPIUniProtKB:P04062HumanPMID:24162852
Molecular FunctionGO:0005515protein bindingSCARB2IPIUniProtKB:O60883HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSCARB2IPIUniProtKB:P31937HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSCARB2IPIUniProtKB:Q86VI4HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSCARB2IPIUniProtKB:Q8N6F1-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSCARB2IPIUniProtKB:Q8TED1HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSCARB2IPIUniProtKB:Q9Y282HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingScarb2IPIUniProtKB:P17439MouseMGI:MGI:6274951|PMID:27789271
Molecular FunctionGO:0042803protein homodimerization activitySCARB2IPIUniProtKB:Q14108HumanPMID:29199275
Molecular FunctionGO:0042803protein homodimerization activityScarb2IPIUniProtKB:O35114MouseMGI:MGI:6112073|PMID:29199275
Molecular FunctionGO:0051087protein-folding chaperone bindingScarb2IPIUniProtKB:Q61696MouseMGI:MGI:6274951|PMID:27789271
Molecular FunctionGO:0005044scavenger receptor activityScarb2IDAMouseMGI:MGI:6112073|PMID:29199275
Cellular ComponentGO:0030666endocytic vesicle membraneScarb2IDAMouseMGI:MGI:6112073|PMID:29199275
Cellular ComponentGO:0070062extracellular exosomeSCARB2HDAHumanPMID:19056867
Cellular ComponentGO:0070062extracellular exosomeSCARB2HDAHumanPMID:23533145
Cellular ComponentGO:0005925focal adhesionSCARB2HDAHumanPMID:21423176
Cellular ComponentGO:0043202lysosomal lumenScarb2IDAMouseMGI:MGI:3773765|PMID:18022370
Cellular ComponentGO:0005765lysosomal membraneSCARB2HDAHumanPMID:17897319
Cellular ComponentGO:0005765lysosomal membraneScarb2IDAMouseMGI:MGI:3773765|PMID:18022370
Cellular ComponentGO:0016020membraneSCARB2HDAHumanPMID:19946888
Cellular ComponentGO:0005886plasma membraneScarb2IDAMouseMGI:MGI:6112073|PMID:29199275
Biological ProcessGO:0015917aminophospholipid transportScarb2IDAMouseMGI:MGI:6112073|PMID:29199275
Biological ProcessGO:0010467gene expressionScarb2IMPMGI:MGI:2654430MousePMID:16901941
Biological ProcessGO:0030903notochord developmentscarb2aIMPZfishPMID:26743566
Biological ProcessGO:0010976positive regulation of neuron projection developmentScarb2IDARatPMID:23825416|RGD:8655547
Biological ProcessGO:0006622protein targeting to lysosomeSCARB2IMPHumanPMID:18022370
Biological ProcessGO:0006622protein targeting to lysosomeScarb2IMPMouseMGI:MGI:3773765|PMID:18022370
Biological ProcessGO:0006898receptor-mediated endocytosisScarb2IDAMouseMGI:MGI:6112073|PMID:29199275
Biological ProcessGO:0043470regulation of carbohydrate catabolic processSCARB2IMPHumanPMID:18022370
Biological ProcessGO:0043470regulation of carbohydrate catabolic processScarb2IMPMouseMGI:MGI:3773765|PMID:18022370
Biological ProcessGO:1905123regulation of glucosylceramidase activityScarb2IMPMouseMGI:MGI:5609206|PMID:25316793
Biological ProcessGO:0007605sensory perception of soundScarb2IMPMGI:MGI:2654430MousePMID:16901941

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/03/2024
MGI 6.24
The Jackson Laboratory