Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SCD
  • Mouse genes Scd1
  • Rat genes Scd
  • Zfish genes scd,scdb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Scd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005506	iron ion binding	SCD	IDA		Human	PMID:18765284
Molecular Function	GO:0005506	iron ion binding	Scd	IDA		Rat	PMID:2892838|RGD:10054074
Molecular Function	GO:0046872	metal ion binding	Scd1	IDA		Mouse	MGI:MGI:5646337|PMID:26098370
Molecular Function	GO:0016491	oxidoreductase activity	SCD	IDA		Human	PMID:15907797
Molecular Function	GO:0016491	oxidoreductase activity	SCD	IDA		Human	PMID:18765284
Molecular Function	GO:0016491	oxidoreductase activity	Scd	IMP		Rat	PMID:7947684|RGD:10054069
Molecular Function	GO:0032896	palmitoyl-CoA 9-desaturase activity	Scd1	IDA		Mouse	MGI:MGI:5646337|PMID:26098370
Molecular Function	GO:0032896	palmitoyl-CoA 9-desaturase activity	Scd1	IDA		Mouse	PMID:16443825
Molecular Function	GO:0032896	palmitoyl-CoA 9-desaturase activity	Scd1	IGI	SGD:S000003023	Mouse	PMID:16443825
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:A0A142I5B9	Human	PMID:30177828
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:O14880	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:O15393-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:O15529	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:P08034	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:P15151	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:P20138	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:P27105	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:P48051	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:P49447	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q2HXU8-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q3MIR4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q3ZAQ7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q5SR56	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q7Z5P4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q86VR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q8N5M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q8NI22	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q8TBB6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q8TED1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q96MV1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q99942	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q9BQA9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q9BRK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q9BY50	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q9H2K0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q9HA82	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q9NPE6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q9NPL8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q9NX47	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q9NY72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q9UJ71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCD	IPI	UniProtKB:Q9Y320	Human	PMID:32296183
Molecular Function	GO:0004768	stearoyl-CoA 9-desaturase activity	SCD	IDA		Human	PMID:15907797
Molecular Function	GO:0004768	stearoyl-CoA 9-desaturase activity	SCD	IDA		Human	PMID:18765284
Molecular Function	GO:0004768	stearoyl-CoA 9-desaturase activity	Scd1	IDA		Mouse	MGI:MGI:5646337|PMID:26098370
Molecular Function	GO:0004768	stearoyl-CoA 9-desaturase activity	Scd1	IDA		Mouse	MGI:MGI:3623168|PMID:16443825
Molecular Function	GO:0004768	stearoyl-CoA 9-desaturase activity	Scd1	IGI	SGD:S000003023	Mouse	PMID:16443825
Molecular Function	GO:0004768	stearoyl-CoA 9-desaturase activity	Scd1	IDA		Mouse	PMID:16443825
Molecular Function	GO:0004768	stearoyl-CoA 9-desaturase activity	Scd	IDA		Rat	PMID:2892838|RGD:10054074
Molecular Function	GO:0004768	stearoyl-CoA 9-desaturase activity	Scd	IMP		Rat	PMID:7947684|RGD:10054069
Cellular Component	GO:0005783	endoplasmic reticulum	SCD	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	SCD	IDA		Human	PMID:15907797
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Scd1	IDA		Mouse	MGI:MGI:5572876|PMID:16275639
Cellular Component	GO:0016020	membrane	SCD	IDA		Human	PMID:18765284
Cellular Component	GO:0016020	membrane	SCD	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Scd	IDA		Rat	PMID:2892838|RGD:10054074
Cellular Component	GO:0005730	nucleolus	SCD	IDA		Human	GO_REF:0000052
Biological Process	GO:0050873	brown fat cell differentiation	Scd1	IDA		Mouse	PMID:18492766
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Scd1	IMP	MGI:MGI:3620028	Mouse	PMID:16040962
Biological Process	GO:0060613	fat pad development	scd	IMP	ZFIN:ZDB-GENO-221219-1	Zfish	PMID:35252813
Biological Process	GO:0006633	fatty acid biosynthetic process	Scd1	IMP	MGI:MGI:2388371	Mouse	PMID:12815040
Biological Process	GO:0008610	lipid biosynthetic process	Scd	IEP		Rat	PMID:12896875|RGD:1304415
Biological Process	GO:0055088	lipid homeostasis	Scd1	IMP	MGI:MGI:3620028	Mouse	PMID:16040962
Biological Process	GO:1903966	monounsaturated fatty acid biosynthetic process	Scd1	IMP		Mouse	MGI:MGI:1889921|PMID:10899171
Biological Process	GO:1903966	monounsaturated fatty acid biosynthetic process	Scd1	IMP		Mouse	MGI:MGI:5646337|PMID:26098370
Biological Process	GO:1903966	monounsaturated fatty acid biosynthetic process	Scd1	IGI	SGD:S000003023	Mouse	PMID:16443825
Biological Process	GO:1903966	monounsaturated fatty acid biosynthetic process	Scd1	IDA		Mouse	PMID:16443825
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Scd1	IMP		Mouse	MGI:MGI:4359334|PMID:19429677
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Scd1	IMP		Mouse	MGI:MGI:3487220|PMID:15210843
Biological Process	GO:0009617	response to bacterium	Scd1	IEP		Mouse	PMID:23012479
Biological Process	GO:0070542	response to fatty acid	Scd	IDA		Rat	PMID:1982442|RGD:10054070
Biological Process	GO:0048733	sebaceous gland development	Scd1	IMP		Mouse	MGI:MGI:1859469|PMID:10854228
Biological Process	GO:0055092	sterol homeostasis	Scd1	IMP		Mouse	MGI:MGI:1859469|PMID:10854228
Biological Process	GO:0036269	swimming behavior	scdb	IGI	ZFIN:ZDB-CRISPR-220111-5,ZFIN:ZDB-CRISPR-220111-6,ZFIN:ZDB-CRISPR-220111-7,ZFIN:ZDB-CRISPR-220111-8	Zfish	PMID:33690217
Biological Process	GO:0036269	swimming behavior	scd	IGI	ZFIN:ZDB-CRISPR-220111-5,ZFIN:ZDB-CRISPR-220111-6,ZFIN:ZDB-CRISPR-220111-7,ZFIN:ZDB-CRISPR-220111-8	Zfish	PMID:33690217
Biological Process	GO:1903699	tarsal gland development	Scd1	IMP		Mouse	MGI:MGI:1859469|PMID:10854228
Biological Process	GO:0006641	triglyceride metabolic process	Scd1	IMP		Mouse	MGI:MGI:1889921|PMID:10899171
Biological Process	GO:0006636	unsaturated fatty acid biosynthetic process	SCD	IDA		Human	PMID:15907797
Biological Process	GO:0006636	unsaturated fatty acid biosynthetic process	SCD	IDA		Human	PMID:18765284
Biological Process	GO:0006636	unsaturated fatty acid biosynthetic process	Scd	IDA		Rat	PMID:2892838|RGD:10054074
Biological Process	GO:0006636	unsaturated fatty acid biosynthetic process	Scd	IMP		Rat	PMID:7947684|RGD:10054069
Biological Process	GO:0050872	white fat cell differentiation	Scd1	IDA		Mouse	PMID:18492766

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern