Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SCP2
  • Mouse genes Scp2
  • Rat genes Scp2
  • Zfish genes scp2a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Scp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003988	acetyl-CoA C-acyltransferase activity	Scp2	IDA		Rat	PMID:8063752|RGD:9850162
Molecular Function	GO:0003988	acetyl-CoA C-acyltransferase activity	Scp2	IDA		Rat	PMID:9245689|RGD:151356613
Molecular Function	GO:0003988	acetyl-CoA C-acyltransferase activity	Scp2	IDA		Rat	PMID:9325339|RGD:21201257
Molecular Function	GO:0050633	acetyl-CoA C-myristoyltransferase activity	Scp2	IDA		Rat	PMID:9325339|RGD:21201257
Molecular Function	GO:0015485	cholesterol binding	SCP2	IDA		Human	PMID:18465878
Molecular Function	GO:0120020	cholesterol transfer activity	Scp2	IDA		Rat	PMID:8063752|RGD:9850162
Molecular Function	GO:0000062	fatty-acyl-CoA binding	SCP2	IDA		Human	PMID:18465878
Molecular Function	GO:0042802	identical protein binding	Scp2	IPI	RGD:3642	Rat	PMID:10733876|RGD:9850264
Molecular Function	GO:0036042	long-chain fatty acyl-CoA binding	SCP2	IDA		Human	PMID:17418802
Molecular Function	GO:0070538	oleic acid binding	SCP2	IDA		Human	PMID:18465878
Molecular Function	GO:0120019	phosphatidylcholine transfer activity	Scp2	IDA		Rat	PMID:8063752|RGD:9850162
Molecular Function	GO:1904121	phosphatidylethanolamine transfer activity	Scp2	IDA		Rat	PMID:8606365|RGD:9854645
Molecular Function	GO:0050632	propionyl-CoA C2-trimethyltridecanoyltransferase activity	SCP2	EXP		Human	PMID:11734571
Molecular Function	GO:0050632	propionyl-CoA C2-trimethyltridecanoyltransferase activity	SCP2	EXP		Human	PMID:16685654
Molecular Function	GO:0050632	propionyl-CoA C2-trimethyltridecanoyltransferase activity	SCP2	EXP		Human	PMID:9245689
Molecular Function	GO:0050632	propionyl-CoA C2-trimethyltridecanoyltransferase activity	Scp2	IDA		Rat	PMID:9245689|RGD:151356613
Molecular Function	GO:0005515	protein binding	SCP2	IPI	UniProtKB:P49817	Human	PMID:15182174
Molecular Function	GO:0005515	protein binding	SCP2	IPI	UniProtKB:Q03135	Human	PMID:15182174
Molecular Function	GO:0005515	protein binding	SCP2	IPI	UniProtKB:P50542	Human	PMID:19584060
Molecular Function	GO:0005515	protein binding	SCP2	IPI	UniProtKB:Q15645	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	SCP2	IPI	UniProtKB:Q15645	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Scp2	IPI	PR:Q9D828	Mouse	PMID:11591653
Molecular Function	GO:0044877	protein-containing complex binding	Scp2	IDA		Rat	PMID:10733876|RGD:9850264
Molecular Function	GO:0005102	signaling receptor binding	SCP2	IPI	UniProtKB:P50542	Human	PMID:21375735
Cellular Component	GO:0005737	cytoplasm	Scp2	IDA		Mouse	MGI:MGI:6255511|PMID:26901662
Cellular Component	GO:0005737	cytoplasm	Scp2	IDA		Rat	PMID:2223868|RGD:9850262
Cellular Component	GO:0005829	cytosol	Scp2	IDA		Rat	PMID:2925789|RGD:9850266
Cellular Component	GO:0005829	cytosol	Scp2	IDA		Rat	PMID:8847489|RGD:9850161
Cellular Component	GO:0005783	endoplasmic reticulum	Scp2	IDA		Mouse	MGI:MGI:6467919|PMID:11003606
Cellular Component	GO:0005783	endoplasmic reticulum	Scp2	IDA		Rat	PMID:2925789|RGD:9850266
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SCP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	SCP2	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Scp2	IDA		Rat	PMID:1374267|RGD:9850256
Cellular Component	GO:0005739	mitochondrion	Scp2	IDA		Mouse	MGI:MGI:6255511|PMID:26901662
Cellular Component	GO:0005739	mitochondrion	Scp2	IDA		Mouse	MGI:MGI:6467919|PMID:11003606
Cellular Component	GO:0005739	mitochondrion	Scp2	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Scp2	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Scp2	IDA		Rat	PMID:2925789|RGD:9850266
Cellular Component	GO:0005739	mitochondrion	Scp2	IDA		Rat	PMID:3768356|RGD:9850281
Cellular Component	GO:0005654	nucleoplasm	SCP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Scp2	IDA		Rat	PMID:3030719|RGD:9999179
Cellular Component	GO:0005782	peroxisomal matrix	Scp2	IDA		Rat	PMID:8063752|RGD:9850162
Cellular Component	GO:0005777	peroxisome	SCP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005777	peroxisome	SCP2	IDA		Human	PMID:1347505
Cellular Component	GO:0005777	peroxisome	SCP2	IDA		Human	PMID:21375735
Cellular Component	GO:0005777	peroxisome	Scp2	IDA		Mouse	MGI:MGI:6255511|PMID:26901662
Cellular Component	GO:0005777	peroxisome	Scp2	IDA		Mouse	MGI:MGI:6467919|PMID:11003606
Cellular Component	GO:0005777	peroxisome	Scp2	IDA		Rat	PMID:14561759|RGD:1580664
Cellular Component	GO:0005777	peroxisome	Scp2	IDA		Rat	PMID:9325339|RGD:21201257
Cellular Component	GO:0032991	protein-containing complex	SCP2	IDA		Human	PMID:19584060
Biological Process	GO:0007568	aging	Scp2	IDA		Rat	PMID:7121212|RGD:9850269
Biological Process	GO:0008206	bile acid metabolic process	Scp2	IDA		Rat	PMID:9325339|RGD:21201257
Biological Process	GO:0071397	cellular response to cholesterol	Scp2	IEP		Rat	PMID:7989577|RGD:9850255
Biological Process	GO:0071397	cellular response to cholesterol	Scp2	IEP		Rat	PMID:8847489|RGD:9850161
Biological Process	GO:0006635	fatty acid beta-oxidation	Scp2	IDA		Rat	PMID:9325339|RGD:21201257
Biological Process	GO:1901373	lipid hydroperoxide transport	SCP2	IDA		Human	PMID:15449949
Biological Process	GO:0043065	positive regulation of apoptotic process	Scp2	IDA		Rat	PMID:16772292|RGD:9850270
Biological Process	GO:0045542	positive regulation of cholesterol biosynthetic process	Scp2	IDA		Rat	PMID:2554812|RGD:9850260
Biological Process	GO:1904109	positive regulation of cholesterol import	Scp2	IDA		Rat	PMID:16772292|RGD:9850270
Biological Process	GO:0032385	positive regulation of intracellular cholesterol transport	SCP2	IDA		Human	PMID:15449949
Biological Process	GO:0010893	positive regulation of steroid biosynthetic process	Scp2	IDA		Rat	PMID:1703300|RGD:8554045
Biological Process	GO:0010893	positive regulation of steroid biosynthetic process	Scp2	IMP		Rat	PMID:3030719|RGD:9999179
Biological Process	GO:0071071	regulation of phospholipid biosynthetic process	Scp2	IDA		Mouse	MGI:MGI:6467919|PMID:11003606
Biological Process	GO:0032355	response to estradiol	Scp2	IEP		Rat	PMID:2474437|RGD:9850268
Biological Process	GO:0034699	response to luteinizing hormone	Scp2	IEP		Rat	PMID:2249635|RGD:9850257

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern