Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SCRT1
  • Mouse genes Scrt1
  • Rat genes Scrt1
  • Zfish genes scrt1a,scrt1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Scrt1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	SCRT1	IDA		Human	PMID:11274425
Molecular Function	GO:0005515	protein binding	Scrt1	IPI	UniProtKB:Q7TQJ8|UniProtKB:Q91XC0|UniProtKB:Q9QXD8	Mouse	MGI:MGI:5318024|PMID:18331720
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	SCRT1	IDA		Human	PMID:11274425
Molecular Function	GO:0043565	sequence-specific DNA binding	SCRT1	IDA		Human	PMID:23332764
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	SCRT1	IDA		Human	PMID:28473536
Cellular Component	GO:0016604	nuclear body	SCRT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Scrt1	IDA		Mouse	PMID:23434913
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SCRT1	IDA		Human	PMID:11274425
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Scrt1	IDA		Mouse	PMID:23434913
Biological Process	GO:2001222	regulation of neuron migration	Scrt1	IMP		Mouse	PMID:23434913

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern