Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SCT
  • Mouse genes Sct
  • Rat genes Sct
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sct

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046659	digestive hormone activity	Sct	IDA		Rat	PMID:3047699|RGD:9590242
Molecular Function	GO:0001664	G protein-coupled receptor binding	SCT	IPI	UniProtKB:P47872	Human	PMID:7612008
Molecular Function	GO:0005179	hormone activity	Sct	IDA		Rat	PMID:19805236|RGD:14397557
Molecular Function	GO:0005515	protein binding	SCT	IPI	UniProtKB:O14770-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCT	IPI	UniProtKB:O14964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCT	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SCT	IPI	UniProtKB:Q8N6Y0	Human	PMID:32296183
Cellular Component	GO:0005615	extracellular space	Sct	IDA		Rat	PMID:19805236|RGD:14397557
Cellular Component	GO:0005615	extracellular space	Sct	IDA		Rat	PMID:3047699|RGD:9590242
Biological Process	GO:0007420	brain development	Sct	IEP		Rat	PMID:15276242|RGD:9590241
Biological Process	GO:0021542	dentate gyrus development	Sct	IMP	MGI:MGI:3815315	Mouse	PMID:21159798
Biological Process	GO:0002024	diet induced thermogenesis	Sct	IDA		Mouse	MGI:MGI:6259360|PMID:30449620
Biological Process	GO:0048566	embryonic digestive tract development	Sct	IEP		Rat	PMID:1711228|RGD:729899
Biological Process	GO:0021766	hippocampus development	Sct	IMP		Mouse	MGI:MGI:3814626|PMID:18534766
Biological Process	GO:0009992	intracellular water homeostasis	Sct	IDA		Rat	PMID:19805236|RGD:14397557
Biological Process	GO:1903640	negative regulation of gastrin-induced gastric acid secretion	Sct	IDA		Rat	PMID:11123201|RGD:9590235
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Sct	IMP	MGI:MGI:3815315	Mouse	PMID:21159798
Biological Process	GO:0051402	neuron apoptotic process	Sct	IMP	MGI:MGI:3815315	Mouse	PMID:21159798
Biological Process	GO:0097150	neuronal stem cell population maintenance	Sct	IMP	MGI:MGI:3815315	Mouse	PMID:21159798
Biological Process	GO:0043950	positive regulation of cAMP-mediated signaling	Sct	IDA		Rat	PMID:12403838|RGD:9590237
Biological Process	GO:0050996	positive regulation of lipid catabolic process	Sct	IMP		Mouse	MGI:MGI:5562611|PMID:24273196
Biological Process	GO:0050996	positive regulation of lipid catabolic process	Sct	IDA		Mouse	MGI:MGI:6259360|PMID:30449620
Biological Process	GO:0090187	positive regulation of pancreatic juice secretion	Sct	IDA		Rat	PMID:11123201|RGD:9590235
Biological Process	GO:0090274	positive regulation of somatostatin secretion	Sct	IDA		Rat	PMID:11123201|RGD:9590235
Biological Process	GO:0032098	regulation of appetite	Sct	IDA		Mouse	MGI:MGI:6259360|PMID:30449620
Biological Process	GO:0032098	regulation of appetite	Sct	IMP		Mouse	MGI:MGI:6294194|PMID:20927047
Biological Process	GO:0048167	regulation of synaptic plasticity	Sct	IMP		Mouse	MGI:MGI:3814626|PMID:18534766
Biological Process	GO:0031667	response to nutrient levels	Sct	IDA		Mouse	MGI:MGI:6259360|PMID:30449620
Biological Process	GO:0008542	visual learning	Sct	IMP	MGI:MGI:3815315	Mouse	PMID:21159798

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern