Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SDHAF2
  • Mouse genes Sdhaf2
  • Rat genes Sdhaf2
  • Zfish genes sdhaf2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sdhaf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SDHAF2	IPI	UniProtKB:P31040	Human	PMID:19628817
Molecular Function	GO:0005515	protein binding	SDHAF2	IPI	UniProtKB:P31040	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	SDHAF2	IPI	UniProtKB:P31040	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SDHAF2	IPI	UniProtKB:P78329	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SDHAF2	IPI	UniProtKB:Q96IW7	Human	PMID:32296183
Cellular Component	GO:0005829	cytosol	SDHAF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	SDHAF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	SDHAF2	IDA		Human	PMID:19628817
Cellular Component	GO:0005739	mitochondrion	Sdhaf2	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005730	nucleolus	SDHAF2	IDA		Human	GO_REF:0000052
Biological Process	GO:0060070	canonical Wnt signaling pathway	Sdhaf2	IMP		Mouse	PMID:23983127
Biological Process	GO:0001837	epithelial to mesenchymal transition	Sdhaf2	IMP		Mouse	PMID:23983127
Biological Process	GO:0006121	mitochondrial electron transport, succinate to ubiquinone	SDHAF2	IMP		Human	PMID:19628817
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	SDHAF2	IGI	UniProtKB:P35222	Human	PMID:23983127
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Sdhaf2	IMP		Mouse	PMID:23983127
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	SDHAF2	IMP		Human	PMID:23983127
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	Sdhaf2	IMP		Mouse	PMID:23983127
Biological Process	GO:0006470	protein dephosphorylation	SDHAF2	IGI	UniProtKB:P67775	Human	PMID:23983127
Biological Process	GO:0006470	protein dephosphorylation	Sdhaf2	IMP		Mouse	PMID:23983127
Biological Process	GO:0018293	protein-FAD linkage	SDHAF2	IMP		Human	PMID:19628817

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern