Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SDHAF4
  • Mouse genes Sdhaf4
  • Rat genes Sdhaf4
  • Zfish genes sdhaf4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sdhaf4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008047	enzyme activator activity	Sdhaf4	IMP		Mouse	MGI:MGI:5605436|PMID:24954416
Molecular Function	GO:0005515	protein binding	SDHAF4	IPI	UniProtKB:O43169	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SDHAF4	IPI	UniProtKB:O75841	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SDHAF4	IPI	UniProtKB:P60033	Human	PMID:32296183
Cellular Component	GO:0005739	mitochondrion	Sdhaf4	HDA		Mouse	PMID:18614015
Biological Process	GO:0045333	cellular respiration	SDHAF4	IGI	UniProtKB:P38345	Human	PMID:24954416
Biological Process	GO:0045333	cellular respiration	Sdhaf4	IMP		Mouse	MGI:MGI:5605436|PMID:24954416
Biological Process	GO:0045087	innate immune response	Sdhaf4	IMP		Mouse	PMID:19805818
Biological Process	GO:0034553	mitochondrial respiratory chain complex II assembly	SDHAF4	IGI	UniProtKB:P38345	Human	PMID:24954416
Biological Process	GO:0034553	mitochondrial respiratory chain complex II assembly	Sdhaf4	IMP		Mouse	MGI:MGI:5605436|PMID:24954416
Biological Process	GO:1904231	positive regulation of succinate dehydrogenase activity	Sdhaf4	IMP		Mouse	MGI:MGI:5605436|PMID:24954416

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern