Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SEC14L2
  • Mouse genes Sec14l2
  • Rat genes Sec14l2
  • Zfish genes sec14l7,sec14l8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sec14l2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008047	enzyme activator activity	Sec14l2	IDA		Rat	PMID:11226224|RGD:727312
Molecular Function	GO:0005525	GTP binding	sec14l8	IDA		Zfish	PMID:28463110
Molecular Function	GO:0032794	GTPase activating protein binding	sec14l8	IPI	ZFIN:ZDB-GENE-050208-654	Zfish	PMID:28463110
Molecular Function	GO:0003924	GTPase activity	sec14l8	IDA		Zfish	PMID:28463110
Molecular Function	GO:0005515	protein binding	sec14l8	IPI	ZFIN:ZDB-GENE-050208-654	Zfish	PMID:28463110
Molecular Function	GO:0005515	protein binding	sec14l8	IPI	ZFIN:ZDB-GENE-081222-2	Zfish	PMID:28463110
Molecular Function	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	Sec14l2	IDA		Rat	PMID:11226224|RGD:727312
Cellular Component	GO:0005829	cytosol	SEC14L2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Sec14l2	IDA		Rat	PMID:11226224|RGD:727312
Cellular Component	GO:0070062	extracellular exosome	SEC14L2	HDA		Human	PMID:23533145
Cellular Component	GO:0005654	nucleoplasm	SEC14L2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	sec14l8	IDA		Zfish	PMID:28463110
Biological Process	GO:0035479	angioblast cell migration from lateral mesoderm to midline	sec14l8	IMP	ZFIN:ZDB-GENO-200409-6	Zfish	PMID:30962435
Biological Process	GO:0045542	positive regulation of cholesterol biosynthetic process	Sec14l2	IDA		Rat	PMID:11226224|RGD:727312
Biological Process	GO:1904088	positive regulation of epiboly involved in gastrulation with mouth forming second	sec14l8	IGI	ZFIN:ZDB-GENE-050208-654	Zfish	PMID:28463110
Biological Process	GO:1904088	positive regulation of epiboly involved in gastrulation with mouth forming second	sec14l8	IMP	ZFIN:ZDB-GENO-171109-4	Zfish	PMID:28463110
Biological Process	GO:1901232	regulation of convergent extension involved in axis elongation	sec14l8	IMP	ZFIN:ZDB-GENO-171109-4	Zfish	PMID:28463110
Biological Process	GO:1901232	regulation of convergent extension involved in axis elongation	sec14l8	IGI	ZFIN:ZDB-GENE-050208-654	Zfish	PMID:28463110
Biological Process	GO:0007223	Wnt signaling pathway, calcium modulating pathway	sec14l8	IMP	ZFIN:ZDB-GENO-171109-4	Zfish	PMID:28463110
Biological Process	GO:0007223	Wnt signaling pathway, calcium modulating pathway	sec14l8	IGI	ZFIN:ZDB-GENE-050208-654	Zfish	PMID:28463110

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern