Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SEC16A
  • Mouse genes Sec16a
  • Rat genes Sec16a
  • Zfish genes sec16a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sec16a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SEC16A	IPI	UniProtKB:P55735	Human	PMID:17428803
Molecular Function	GO:0005515	protein binding	SEC16A	IPI	UniProtKB:Q01405	Human	PMID:17428803
Molecular Function	GO:0005515	protein binding	SEC16A	IPI	UniProtKB:P55735	Human	PMID:19638414
Molecular Function	GO:0005515	protein binding	SEC16A	IPI	UniProtKB:Q96JE7	Human	PMID:22355596
Molecular Function	GO:0005515	protein binding	SEC16A	IPI	UniProtKB:P55735	Human	PMID:25201882
Molecular Function	GO:0005515	protein binding	SEC16A	IPI	UniProtKB:Q5S007	Human	PMID:25201882
Molecular Function	GO:0005515	protein binding	SEC16A	IPI	UniProtKB:Q9H8Y8	Human	PMID:28067262
Molecular Function	GO:0005515	protein binding	SEC16A	IPI	UniProtKB:Q5JRA6	Human	PMID:28442536
Molecular Function	GO:0005515	protein binding	SEC16A	IPI	UniProtKB:Q6ZNJ1	Human	PMID:29187380
Molecular Function	GO:0005515	protein binding	SEC16A	IPI	UniProtKB:Q96N67	Human	PMID:29187380
Molecular Function	GO:0005515	protein binding	SEC16A	IPI	UniProtKB:Q8BG47	Human	PMID:29300766
Molecular Function	GO:0005515	protein binding	SEC16A	IPI	UniProtKB:Q8QZS5	Human	PMID:29300766
Molecular Function	GO:0005515	protein binding	SEC16A	IPI	UniProtKB:Q5S007	Human	PMID:31046837
Molecular Function	GO:0005515	protein binding	Sec16a	IPI	UniProtKB:Q5S006	Mouse	MGI:MGI:5608715|PMID:25201882
Molecular Function	GO:0005515	protein binding	Sec16a	IPI	UniProtKB:Q01405	Mouse	MGI:MGI:6211123|PMID:17428803
Molecular Function	GO:0005515	protein binding	Sec16a	IPI	UniProtKB:P61027	Mouse	MGI:MGI:5807293|PMID:27354378
Cellular Component	GO:0005829	cytosol	SEC16A	IDA		Human	PMID:17428803
Cellular Component	GO:0005829	cytosol	SEC16A	IDA		Human	PMID:21768384
Cellular Component	GO:0070971	endoplasmic reticulum exit site	SEC16A	IDA		Human	PMID:19638414
Cellular Component	GO:0070971	endoplasmic reticulum exit site	SEC16A	IDA		Human	PMID:22355596
Cellular Component	GO:0070971	endoplasmic reticulum exit site	SEC16A	IDA		Human	PMID:25201882
Cellular Component	GO:0070971	endoplasmic reticulum exit site	SEC16A	IDA		Human	PMID:28067262
Cellular Component	GO:0070971	endoplasmic reticulum exit site	Sec16a	IDA		Mouse	MGI:MGI:5608715|PMID:25201882
Cellular Component	GO:0005789	endoplasmic reticulum membrane	SEC16A	IDA		Human	PMID:29300766
Cellular Component	GO:0031090	organelle membrane	SEC16A	IDA		Human	PMID:17428803
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Sec16a	IDA		Mouse	MGI:MGI:5807293|PMID:27354378
Biological Process	GO:0007029	endoplasmic reticulum organization	SEC16A	IMP		Human	PMID:17428803
Biological Process	GO:0007029	endoplasmic reticulum organization	SEC16A	IDA		Human	PMID:21768384
Biological Process	GO:0007029	endoplasmic reticulum organization	SEC16A	IMP		Human	PMID:28442536
Biological Process	GO:0007029	endoplasmic reticulum organization	Sec16a	IMP		Mouse	MGI:MGI:6211123|PMID:17428803
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	SEC16A	IMP		Human	PMID:22355596
Biological Process	GO:0006893	Golgi to plasma membrane transport	SEC16A	IMP		Human	PMID:28067262
Biological Process	GO:0032527	protein exit from endoplasmic reticulum	Sec16a	IMP		Mouse	MGI:MGI:5807293|PMID:27354378
Biological Process	GO:0070973	protein localization to endoplasmic reticulum exit site	SEC16A	IMP		Human	PMID:28442536
Biological Process	GO:0072659	protein localization to plasma membrane	Sec16a	IMP		Mouse	MGI:MGI:5807293|PMID:27354378
Biological Process	GO:0050821	protein stabilization	SEC16A	IMP		Human	PMID:29300766
Biological Process	GO:0034976	response to endoplasmic reticulum stress	SEC16A	IDA		Human	PMID:28067262
Biological Process	GO:0021762	substantia nigra development	SEC16A	HEP		Human	PMID:22926577

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern