Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SELENOT
  • Mouse genes Selenot
  • Rat genes Selenot
  • Zfish genes selenot1a,selenot1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Selenot

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004791	thioredoxin-disulfide reductase activity	Selenot	IDA		Rat	PMID:26866473|RGD:12793008
Cellular Component	GO:0005783	endoplasmic reticulum	Selenot	IDA		Mouse	PMID:23913443
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Selenot	IDA		Rat	PMID:18198219|RGD:2325273
Biological Process	GO:0045454	cell redox homeostasis	SELENOT	IDA		Human	PMID:26866473
Biological Process	GO:0045454	cell redox homeostasis	Selenot	IMP		Mouse	MGI:MGI:5883196|PMID:26866473
Biological Process	GO:0098869	cellular oxidant detoxification	Selenot	IDA		Rat	PMID:26866473|RGD:12793008
Biological Process	GO:0042593	glucose homeostasis	Selenot	IMP	MGI:MGI:5544732	Mouse	PMID:23913443
Biological Process	GO:0035773	insulin secretion involved in cellular response to glucose stimulus	Selenot	IMP	MGI:MGI:5544732	Mouse	PMID:23913443
Biological Process	GO:0031016	pancreas development	Selenot	IMP	MGI:MGI:5544732	Mouse	PMID:23913443
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Selenot	IMP		Rat	PMID:18198219|RGD:2325273
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Selenot	IMP		Rat	PMID:26779623|RGD:12793001
Biological Process	GO:0060124	positive regulation of growth hormone secretion	Selenot	IMP		Rat	PMID:18198219|RGD:2325273
Biological Process	GO:0009749	response to glucose	Selenot	IMP	MGI:MGI:5544732	Mouse	PMID:23913443

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern