Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SELP
  • Mouse genes Selp
  • Rat genes Selp
  • Zfish genes selp
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Selp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	SELP	IDA		Human	PMID:11081633
Molecular Function	GO:0048306	calcium-dependent protein binding	Selp	IDA		Mouse	PMID:7524641
Molecular Function	GO:0042806	fucose binding	SELP	IDA		Human	PMID:7680663
Molecular Function	GO:0008201	heparin binding	SELP	IDA		Human	PMID:7680663
Molecular Function	GO:0001530	lipopolysaccharide binding	SELP	IMP		Human	PMID:16514062
Molecular Function	GO:0070492	oligosaccharide binding	SELP	IDA		Human	PMID:11081633
Molecular Function	GO:0070492	oligosaccharide binding	SELP	IDA		Human	PMID:28011641
Molecular Function	GO:0070492	oligosaccharide binding	SELP	IDA		Human	PMID:7680663
Molecular Function	GO:0005515	protein binding	SELP	IPI	UniProtKB:Q14242	Human	PMID:11081633
Molecular Function	GO:0005515	protein binding	SELP	IPI	UniProtKB:Q15036	Human	PMID:11237770
Molecular Function	GO:0005515	protein binding	SELP	IPI	UniProtKB:P25063	Human	PMID:15633604
Molecular Function	GO:0005515	protein binding	SELP	IPI	UniProtKB:Q9NZ53	Human	PMID:18606703
Molecular Function	GO:0005515	protein binding	SELP	IPI	UniProtKB:Q14242	Human	PMID:19118202
Molecular Function	GO:0005515	protein binding	SELP	IPI	UniProtKB:Q14242	Human	PMID:26627825
Molecular Function	GO:0005515	protein binding	SELP	IPI	UniProtKB:Q2FZB8	Human	PMID:26627825
Molecular Function	GO:0005515	protein binding	SELP	IPI	UniProtKB:Q14242	Human	PMID:28011641
Molecular Function	GO:0005515	protein binding	SELP	IPI	UniProtKB:P25063	Human	PMID:9129046
Molecular Function	GO:0005515	protein binding	Selp	IPI	PR:P24807	Mouse	PMID:8562500
Molecular Function	GO:0005515	protein binding	Selp	IPI	PR:P24807	Mouse	PMID:7524641
Molecular Function	GO:0005515	protein binding	Selp	IPI	PR:P24807	Mouse	PMID:9048906
Molecular Function	GO:0005515	protein binding	Selp	IPI	UniProtKB:Q15036	Mouse	PMID:23382219
Molecular Function	GO:0033691	sialic acid binding	SELP	IDA		Human	PMID:7680663
Molecular Function	GO:0033691	sialic acid binding	Selp	IDA		Mouse	PMID:8562500
Cellular Component	GO:0009897	external side of plasma membrane	SELP	IDA		Human	PMID:16514062
Cellular Component	GO:0009897	external side of plasma membrane	Selp	IDA		Mouse	PMID:17114491
Cellular Component	GO:0009897	external side of plasma membrane	Selp	IDA		Mouse	PMID:8562500
Cellular Component	GO:0009897	external side of plasma membrane	Selp	IDA		Mouse	PMID:23583643
Cellular Component	GO:0009897	external side of plasma membrane	Selp	IDA		Mouse	PMID:19349303
Cellular Component	GO:0009897	external side of plasma membrane	Selp	IDA		Rat	PMID:14963004|RGD:1599979
Cellular Component	GO:0005615	extracellular space	SELP	IDA		Human	PMID:9290466
Cellular Component	GO:0005615	extracellular space	Selp	IDA		Rat	PMID:18471420|RGD:2312294
Cellular Component	GO:0016020	membrane	Selp	IDA		Mouse	PMID:15956287
Cellular Component	GO:0016020	membrane	Selp	IDA		Mouse	PMID:7688665
Cellular Component	GO:0005886	plasma membrane	SELP	IDA		Human	PMID:28011641
Cellular Component	GO:0031092	platelet alpha granule membrane	SELP	IDA		Human	PMID:15297306
Biological Process	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	SELP	IMP		Human	PMID:28011641
Biological Process	GO:0035584	calcium-mediated signaling using intracellular calcium source	SELP	IGI	UniProtKB:P20160	Human	PMID:15879141
Biological Process	GO:0098609	cell-cell adhesion	Selp	IMP		Rat	PMID:14963004|RGD:1599979
Biological Process	GO:0035701	hematopoietic stem cell migration	selp	IMP	ZFIN:ZDB-MRPHLNO-151124-8	Zfish	PMID:25931248
Biological Process	GO:0097241	hematopoietic stem cell migration to bone marrow	selp	IMP	ZFIN:ZDB-MRPHLNO-151124-8	Zfish	PMID:25931248
Biological Process	GO:0030097	hemopoiesis	selp	IMP	ZFIN:ZDB-MRPHLNO-151124-8	Zfish	PMID:25931248
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	Selp	IMP		Mouse	PMID:8557754
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	Selp	IMP		Mouse	PMID:8562500
Biological Process	GO:0006954	inflammatory response	Selp	IMP	MGI:MGI:1857245	Mouse	PMID:7688665
Biological Process	GO:0007159	leukocyte cell-cell adhesion	SELP	IDA		Human	PMID:7680663
Biological Process	GO:0007159	leukocyte cell-cell adhesion	Selp	IMP		Mouse	PMID:8562500
Biological Process	GO:0007159	leukocyte cell-cell adhesion	Selp	IMP		Mouse	PMID:8557754
Biological Process	GO:0050900	leukocyte migration	Selp	IMP	MGI:MGI:1857245	Mouse	PMID:15484189
Biological Process	GO:0050900	leukocyte migration	Selp	IGI	MGI:MGI:98278	Mouse	PMID:17114491
Biological Process	GO:0050900	leukocyte migration	Selp	IMP		Mouse	PMID:17114491
Biological Process	GO:0050900	leukocyte migration	Selp	IMP		Rat	PMID:12377736|RGD:729766
Biological Process	GO:0050901	leukocyte tethering or rolling	SELP	IMP		Human	PMID:28011641
Biological Process	GO:0050901	leukocyte tethering or rolling	Selp	IMP	MGI:MGI:1857245	Mouse	PMID:15956287
Biological Process	GO:0045785	positive regulation of cell adhesion	Selp	IMP		Rat	PMID:19451746|RGD:2312307
Biological Process	GO:0002687	positive regulation of leukocyte migration	Selp	IGI	MGI:MGI:98278	Mouse	PMID:17114491
Biological Process	GO:0002687	positive regulation of leukocyte migration	Selp	IMP		Mouse	PMID:17114491
Biological Process	GO:1903238	positive regulation of leukocyte tethering or rolling	Selp	IMP		Mouse	MGI:MGI:1860416|PMID:10894166
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	SELP	IDA		Human	PMID:17632516
Biological Process	GO:0010572	positive regulation of platelet activation	Selp	IMP		Mouse	MGI:MGI:3838274|PMID:16514062
Biological Process	GO:0002691	regulation of cellular extravasation	Selp	IMP		Rat	PMID:12081568|RGD:1566567
Biological Process	GO:0033623	regulation of integrin activation	SELP	IMP		Human	PMID:17632516
Biological Process	GO:0032496	response to lipopolysaccharide	Selp	IEP		Rat	PMID:7520013|RGD:729708
Biological Process	GO:0014070	response to organic cyclic compound	Selp	IEP		Rat	PMID:18095572|RGD:2312301

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern