Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SEMA3E
  • Mouse genes Sema3e
  • Rat genes Sema3e
  • Zfish genes sema3e
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sema3e

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0038191	neuropilin binding	sema3e	IDA		Zfish	PMID:31349972
Molecular Function	GO:0005515	protein binding	SEMA3E	IPI	UniProtKB:Q9Y4D7	Human	PMID:17318185
Molecular Function	GO:0005515	protein binding	Sema3e	IPI	UniProtKB:Q9Y4D7	Mouse	MGI:MGI:5538431|PMID:24139859
Molecular Function	GO:0048018	receptor ligand activity	SEMA3E	IDA		Human	PMID:25985275
Molecular Function	GO:0030215	semaphorin receptor binding	SEMA3E	IPI	UniProtKB:Q3UH93	Human	PMID:25985275
Molecular Function	GO:0030215	semaphorin receptor binding	Sema3e	IPI	UniProtKB:Q9Y4D7	Mouse	MGI:MGI:5574548|PMID:24841563
Cellular Component	GO:0005615	extracellular space	Sema3e	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	Sema3e	IMP		Mouse	MGI:MGI:3526793|PMID:15550623
Biological Process	GO:0021828	gonadotrophin-releasing hormone neuronal migration to the hypothalamus	SEMA3E	IDA		Human	PMID:25985275
Biological Process	GO:0016525	negative regulation of angiogenesis	Sema3e	IMP		Mouse	MGI:MGI:4819325|PMID:20385769
Biological Process	GO:0001953	negative regulation of cell-matrix adhesion	Sema3e	IMP		Mouse	MGI:MGI:4819325|PMID:20385769
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	SEMA3E	IDA		Human	PMID:25985275
Biological Process	GO:0001755	neural crest cell migration	sema3e	IMP	ZFIN:ZDB-MRPHLNO-130827-1	Zfish	PMID:31464029
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	SEMA3E	IDA		Human	PMID:25985275
Biological Process	GO:2000249	regulation of actin cytoskeleton reorganization	Sema3e	IMP		Mouse	MGI:MGI:4819325|PMID:20385769
Biological Process	GO:0008360	regulation of cell shape	Sema3e	IMP		Mouse	MGI:MGI:3526793|PMID:15550623
Biological Process	GO:0008360	regulation of cell shape	Sema3e	IMP		Mouse	MGI:MGI:4819325|PMID:20385769
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	SEMA3E	IGI	UniProtKB:Q3UH93	Human	PMID:25985275
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Sema3e	IMP		Mouse	MGI:MGI:3526793|PMID:15550623
Biological Process	GO:0002040	sprouting angiogenesis	Sema3e	IMP		Mouse	MGI:MGI:4819325|PMID:20385769
Biological Process	GO:0002040	sprouting angiogenesis	sema3e	IMP	ZFIN:ZDB-MRPHLNO-100510-4	Zfish	PMID:19422817
Biological Process	GO:0002040	sprouting angiogenesis	sema3e	IMP	ZFIN:ZDB-MRPHLNO-100510-5	Zfish	PMID:19422817
Biological Process	GO:0050808	synapse organization	Sema3e	IMP		Mouse	MGI:MGI:5311980|PMID:22179111

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern