Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SEPTIN2
  • Mouse genes Septin2
  • Rat genes Septin2
  • Zfish genes septin2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Septin2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	SEPTIN2	HDA		Human	PMID:25468996
Molecular Function	GO:0030234	enzyme regulator activity	Septin2	IDA		Mouse	PMID:14723703
Molecular Function	GO:0005515	protein binding	SEPTIN2	IPI	UniProtKB:Q16623	Human	PMID:10321247
Molecular Function	GO:0005515	protein binding	SEPTIN2	IPI	UniProtKB:Q99719	Human	PMID:10321247
Molecular Function	GO:0005515	protein binding	SEPTIN2	IPI	UniProtKB:Q14141	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	SEPTIN2	IPI	UniProtKB:Q14141	Human	PMID:17229681
Molecular Function	GO:0005515	protein binding	SEPTIN2	IPI	UniProtKB:Q4V8G5	Human	PMID:17685441
Molecular Function	GO:0005515	protein binding	SEPTIN2	IPI	UniProtKB:Q14141	Human	PMID:17803907
Molecular Function	GO:0005515	protein binding	SEPTIN2	IPI	UniProtKB:Q99719	Human	PMID:18330356
Molecular Function	GO:0005515	protein binding	SEPTIN2	IPI	UniProtKB:Q14141	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SEPTIN2	IPI	UniProtKB:Q99719	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SEPTIN2	IPI	UniProtKB:Q9H8W4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SEPTIN2	IPI	UniProtKB:Q14141	Human	PMID:25588830
Molecular Function	GO:0005515	protein binding	SEPTIN2	IPI	UniProtKB:Q8IYM1	Human	PMID:25588830
Molecular Function	GO:0005515	protein binding	SEPTIN2	IPI	UniProtKB:Q8IYY4	Human	PMID:28530676
Molecular Function	GO:0005515	protein binding	SEPTIN2	IPI	UniProtKB:Q14141	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Septin2	IPI	UniProtKB:Q9Z2Q6	Mouse	MGI:MGI:3822234|PMID:18809578
Molecular Function	GO:0005515	protein binding	Septin2	IPI	PR:P56564	Mouse	PMID:14723703
Molecular Function	GO:0005515	protein binding	Septin2	IPI	PR:Q8C456	Mouse	PMID:24302887
Molecular Function	GO:0005515	protein binding	Septin2	IPI	PR:Q9Z2Q6	Mouse	PMID:11739749
Molecular Function	GO:0005515	protein binding	Septin2	IPI	PR:O55131	Mouse	PMID:11739749
Cellular Component	GO:0015629	actin cytoskeleton	SEPTIN2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005930	axoneme	SEPTIN2	IDA		Human	PMID:23572511
Cellular Component	GO:0042995	cell projection	Septin2	IDA		Mouse	PMID:14723703
Cellular Component	GO:0009986	cell surface	Septin2	IDA		Mouse	PMID:14723703
Cellular Component	GO:0060170	ciliary membrane	Septin2	IDA		Mouse	MGI:MGI:4462072|PMID:20558667
Cellular Component	GO:0035869	ciliary transition zone	Septin2	IDA		Mouse	PMID:24302887
Cellular Component	GO:0005737	cytoplasm	SEPTIN2	IDA		Human	PMID:10942595
Cellular Component	GO:0000145	exocyst	Septin2	IDA		Rat	PMID:12544826|RGD:724634
Cellular Component	GO:0070062	extracellular exosome	SEPTIN2	HDA		Human	PMID:20458337
Cellular Component	GO:0045171	intercellular bridge	SEPTIN2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043209	myelin sheath	Septin2	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0097730	non-motile cilium	SEPTIN2	IDA		Human	PMID:23572511
Cellular Component	GO:0005654	nucleoplasm	SEPTIN2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SEPTIN2	IDA		Human	PMID:10942595
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Septin2	IDA		Rat	PMID:12544826|RGD:724634
Cellular Component	GO:0032391	photoreceptor connecting cilium	SEPTIN2	IDA		Human	PMID:23572511
Cellular Component	GO:0005886	plasma membrane	SEPTIN2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Septin2	IDA		Mouse	PMID:14723703
Cellular Component	GO:0031105	septin complex	SEPTIN2	IDA		Human	PMID:23572511
Cellular Component	GO:0031105	septin complex	SEPTIN2	IDA		Human	PMID:25588830
Cellular Component	GO:0031105	septin complex	Septin2	IDA		Mouse	MGI:MGI:3822234|PMID:18809578
Cellular Component	GO:0097227	sperm annulus	SEPTIN2	IDA		Human	PMID:25588830
Cellular Component	GO:0045202	synapse	Septin2	IDA		Mouse	PMID:11739749
Biological Process	GO:0060271	cilium assembly	Septin2	IMP		Mouse	MGI:MGI:5300833|PMID:22179047
Biological Process	GO:0060271	cilium assembly	Septin2	IMP		Mouse	MGI:MGI:4462072|PMID:20558667
Biological Process	GO:0031175	neuron projection development	Septin2	IMP		Rat	PMID:12544826|RGD:724634
Biological Process	GO:0002036	regulation of L-glutamate import across plasma membrane	Septin2	IDA		Mouse	PMID:14723703
Biological Process	GO:0032880	regulation of protein localization	Septin2	IMP		Mouse	PMID:22179047
Biological Process	GO:0032880	regulation of protein localization	Septin2	IDA		Mouse	PMID:14723703
Biological Process	GO:0007224	smoothened signaling pathway	Septin2	IMP		Mouse	MGI:MGI:4462072|PMID:20558667

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern