Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SEPTIN5
  • Mouse genes Septin5
  • Rat genes Septin5
  • Zfish genes septin5a,septin5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Septin5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019003	GDP binding	Septin5	IDA		Rat	PMID:17685441|RGD:8553835
Molecular Function	GO:0005525	GTP binding	Septin5	IDA		Rat	PMID:17685441|RGD:8553835
Molecular Function	GO:0042802	identical protein binding	SEPTIN5	IPI	UniProtKB:Q99719	Human	PMID:15214843
Molecular Function	GO:0042802	identical protein binding	SEPTIN5	IPI	UniProtKB:Q99719	Human	PMID:24722188
Molecular Function	GO:0042802	identical protein binding	SEPTIN5	IPI	UniProtKB:Q99719	Human	PMID:25416956
Molecular Function	GO:0035091	phosphatidylinositol binding	Septin5	IDA		Rat	PMID:17685441|RGD:8553835
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q15019	Human	PMID:10321247
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q16623	Human	PMID:10321247
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q92599	Human	PMID:15214843
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q92599	Human	PMID:16767699
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q9NVA2	Human	PMID:16767699
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q14141	Human	PMID:18330356
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q15019	Human	PMID:18330356
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q9NVA2	Human	PMID:18330356
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:P43356	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q14141	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q15019-3	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q8WYJ6	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q14141	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q15019	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q8WYJ6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q9P0V9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q8WYJ6	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q8IYM1	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:P43356	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q15019-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q8IYM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q8WYJ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q9NVA2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q9NZD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:O75376	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q14141	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q15019-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q8IYM1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SEPTIN5	IPI	UniProtKB:Q8N488	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Septin5	IPI	UniProtKB:O55131|UniProtKB:P28661|UniProtKB:P42208|UniProtKB:Q80UG5|UniProtKB:Q8C1B7|UniProtKB:Q8CHH9|UniProtKB:Q9R1T4|UniProtKB:Q9Z1S5	Mouse	MGI:MGI:3822234|PMID:18809578
Molecular Function	GO:0005515	protein binding	Septin5	IPI	UniProtKB:O35526	Mouse	MGI:MGI:3796969|PMID:17296554
Molecular Function	GO:0005515	protein binding	Septin5	IPI	UniProtKB:O60260	Mouse	MGI:MGI:5430901|PMID:11078524
Molecular Function	GO:0005515	protein binding	Septin5	IPI	PR:O55131	Mouse	PMID:11739749
Molecular Function	GO:0005515	protein binding	Septin5	IPI	PR:O55131	Mouse	PMID:24113571
Molecular Function	GO:0005515	protein binding	Septin5	IPI	PR:P42208	Mouse	PMID:11739749
Molecular Function	GO:0005515	protein binding	Septin5	IPI	UniProtKB:Q4V8G5	Rat	PMID:17685441|RGD:8553835
Molecular Function	GO:0005515	protein binding	Septin5	IPI	UniProtKB:Q9JJM9	Rat	PMID:17685441|RGD:8553835
Molecular Function	GO:0042803	protein homodimerization activity	Septin5	IPI	UniProtKB:Q4V8G5	Rat	PMID:17685441|RGD:8553835
Molecular Function	GO:0019905	syntaxin binding	Septin5	IDA		Rat	PMID:10321247|RGD:1302866
Cellular Component	GO:0043679	axon terminus	Septin5	IDA		Mouse	PMID:11064363
Cellular Component	GO:0044305	calyx of Held	Septin5	IDA		Mouse	PMID:20624595
Cellular Component	GO:0044305	calyx of Held	Septin5	IMP		Mouse	PMID:20624595
Cellular Component	GO:0005938	cell cortex	Septin5	IDA		Mouse	PMID:11064363
Cellular Component	GO:0032154	cleavage furrow	Septin5	IDA		Rat	PMID:17685441|RGD:8553835
Cellular Component	GO:0005886	plasma membrane	SEPTIN5	IDA		Human	PMID:10321247
Cellular Component	GO:0005886	plasma membrane	Septin5	IDA		Rat	PMID:10321247|RGD:1302866
Cellular Component	GO:0098793	presynapse	Septin5	IDA		Mouse	MGI:MGI:3822234|PMID:18809578
Cellular Component	GO:0098793	presynapse	Septin5	IDA		Mouse	PMID:11064363
Cellular Component	GO:0031105	septin complex	Septin5	IDA		Mouse	MGI:MGI:3822234|PMID:18809578
Cellular Component	GO:0031105	septin complex	Septin5	IDA		Rat	PMID:17685441|RGD:8553835
Cellular Component	GO:0001725	stress fiber	Septin5	IDA		Rat	PMID:17685441|RGD:8553835
Cellular Component	GO:0045202	synapse	Septin5	IDA		Mouse	PMID:11739749
Cellular Component	GO:0008021	synaptic vesicle	SEPTIN5	IDA		Human	PMID:10321247
Cellular Component	GO:0008021	synaptic vesicle	Septin5	IDA		Mouse	PMID:11064363
Cellular Component	GO:0008021	synaptic vesicle	Septin5	IDA		Rat	PMID:10321247|RGD:1302866
Cellular Component	GO:0043195	terminal bouton	Septin5	IDA		Mouse	PMID:11064363
Cellular Component	GO:0043195	terminal bouton	Septin5	HDA		Rat	PMID:24876496|RGD:10047219
Biological Process	GO:0030534	adult behavior	Septin5	IMP		Mouse	MGI:MGI:3839687|PMID:19240081
Biological Process	GO:0045921	positive regulation of exocytosis	Septin5	IMP		Rat	PMID:10321247|RGD:1302866
Biological Process	GO:0017157	regulation of exocytosis	SEPTIN5	IMP		Human	PMID:10321247
Biological Process	GO:0099148	regulation of synaptic vesicle docking	Septin5	IMP		Mouse	PMID:20624595
Biological Process	GO:0099148	regulation of synaptic vesicle docking	Septin5	IDA		Mouse	PMID:20624595
Biological Process	GO:0035176	social behavior	Septin5	IMP		Mouse	MGI:MGI:5428355|PMID:22589251
Biological Process	GO:0035176	social behavior	Septin5	IMP		Mouse	MGI:MGI:3839687|PMID:19240081

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern