Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SERPINF1
  • Mouse genes Serpinf1
  • Rat genes Serpinf1
  • Zfish genes serpinf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Serpinf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SERPINF1	IPI	UniProtKB:Q96AD5	Human	PMID:17032652
Molecular Function	GO:0005515	protein binding	SERPINF1	IPI	UniProtKB:Q7L775	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SERPINF1	IPI	UniProtKB:Q7L775	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	SERPINF1	IPI	UniProtKB:Q7L775	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SERPINF1	IPI	UniProtKB:Q96EQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SERPINF1	IPI	UniProtKB:Q9P2X3	Human	PMID:32296183
Cellular Component	GO:0030424	axon	Serpinf1	IDA		Rat	PMID:10411342|RGD:8628906
Cellular Component	GO:0043203	axon hillock	Serpinf1	IDA		Rat	PMID:10411342|RGD:8628906
Cellular Component	GO:0005604	basement membrane	Serpinf1	IDA		Rat	PMID:15616035|RGD:1359799
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SERPINF1	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	SERPINF1	HDA		Human	PMID:28675934
Cellular Component	GO:0070062	extracellular exosome	SERPINF1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	SERPINF1	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	SERPINF1	IDA		Human	PMID:12737624
Cellular Component	GO:0005576	extracellular region	Serpinf1	IDA		Mouse	MGI:MGI:1266859|PMID:9614124
Cellular Component	GO:0005576	extracellular region	Serpinf1	IDA		Rat	PMID:19575033|RGD:8554877
Cellular Component	GO:0005615	extracellular space	SERPINF1	HDA		Human	PMID:20551380
Cellular Component	GO:0005615	extracellular space	Serpinf1	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Serpinf1	IDA		Mouse	PMID:15020256
Cellular Component	GO:0005615	extracellular space	Serpinf1	IDA		Rat	PMID:17653050|RGD:8554888
Cellular Component	GO:0043025	neuronal cell body	Serpinf1	IDA		Rat	PMID:10411342|RGD:8628906
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Serpinf1	IDA		Rat	PMID:10411342|RGD:8628906
Biological Process	GO:0007568	aging	Serpinf1	IEP		Rat	PMID:17936752|RGD:2312350
Biological Process	GO:0071279	cellular response to cobalt ion	Serpinf1	IEP		Rat	PMID:21922517|RGD:8554899
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	Serpinf1	IEP		Rat	PMID:15051476|RGD:2312357
Biological Process	GO:0071333	cellular response to glucose stimulus	Serpinf1	IEP		Rat	PMID:19107574|RGD:8655564
Biological Process	GO:0071300	cellular response to retinoic acid	Serpinf1	IEP		Rat	PMID:15051476|RGD:2312357
Biological Process	GO:0060767	epithelial cell proliferation involved in prostate gland development	Serpinf1	IMP	MGI:MGI:2664515	Mouse	PMID:12740569
Biological Process	GO:0001822	kidney development	Serpinf1	IEP		Rat	PMID:17497179|RGD:2312351
Biological Process	GO:0016525	negative regulation of angiogenesis	SERPINF1	IDA		Human	PMID:11562499
Biological Process	GO:0016525	negative regulation of angiogenesis	Serpinf1	IDA		Mouse	MGI:MGI:3691876|PMID:12632345
Biological Process	GO:0010596	negative regulation of endothelial cell migration	Serpinf1	IMP		Rat	PMID:11792807|RGD:8655543
Biological Process	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	Serpinf1	IMP	MGI:MGI:2664515	Mouse	PMID:12740569
Biological Process	GO:0010629	negative regulation of gene expression	Serpinf1	IMP		Rat	PMID:21922517|RGD:8554899
Biological Process	GO:0050728	negative regulation of inflammatory response	Serpinf1	IMP		Rat	PMID:16368716|RGD:1580133
Biological Process	GO:1901215	negative regulation of neuron death	Serpinf1	IMP		Rat	PMID:22410737|RGD:8554894
Biological Process	GO:0042698	ovulation cycle	Serpinf1	IEP		Rat	PMID:23466670|RGD:8590225
Biological Process	GO:0050769	positive regulation of neurogenesis	SERPINF1	IDA		Human	PMID:8226833
Biological Process	GO:0010976	positive regulation of neuron projection development	Serpinf1	IMP		Rat	PMID:23825416|RGD:8655547
Biological Process	GO:0010447	response to acidic pH	Serpinf1	IEP		Rat	PMID:19575033|RGD:8554877
Biological Process	GO:0046685	response to arsenic-containing substance	Serpinf1	IEP		Rat	PMID:23229538|RGD:8655562
Biological Process	GO:0014070	response to organic cyclic compound	Serpinf1	IDA		Rat	PMID:10360224|RGD:8661651
Biological Process	GO:1901652	response to peptide	Serpinf1	IDA		Rat	PMID:10423332|RGD:1625538
Biological Process	GO:0060041	retina development in camera-type eye	Serpinf1	IEP		Rat	PMID:21738387|RGD:8655555
Biological Process	GO:0007614	short-term memory	Serpinf1	IDA		Rat	PMID:17073149|RGD:2312353

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern