Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SESN1
  • Mouse genes Sesn1
  • Rat genes Sesn1
  • Zfish genes sesn1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sesn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070728	leucine binding	SESN1	IDA		Human	PMID:26449471
Molecular Function	GO:0005515	protein binding	SESN1	IPI	UniProtKB:Q06830	Human	PMID:15105503
Molecular Function	GO:0005515	protein binding	Sesn1	IPI	UniProtKB:Q5VZM2,UniProtKB:Q7L523,UniProtKB:Q9HB90,UniProtKB:Q9NQL2	Mouse	MGI:MGI:5604284|PMID:25259925
Cellular Component	GO:0005737	cytoplasm	SESN1	IDA		Human	PMID:15105503
Cellular Component	GO:0001650	fibrillar center	SESN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SESN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SESN1	IDA		Human	PMID:9926927
Biological Process	GO:0098869	cellular oxidant detoxification	SESN1	IMP		Human	PMID:15105503
Biological Process	GO:0034198	cellular response to amino acid starvation	SESN1	IMP		Human	PMID:25263562
Biological Process	GO:0071230	cellular response to amino acid stimulus	Sesn1	IMP		Mouse	MGI:MGI:5604284|PMID:25259925
Biological Process	GO:0042149	cellular response to glucose starvation	SESN1	IMP		Human	PMID:25263562
Biological Process	GO:0007368	determination of left/right symmetry	sesn1	IMP	ZFIN:ZDB-MRPHLNO-070108-6	Zfish	PMID:17038485
Biological Process	GO:0030308	negative regulation of cell growth	Sesn1	IDA		Mouse	MGI:MGI:5784981|PMID:20203043
Biological Process	GO:1904262	negative regulation of TORC1 signaling	SESN1	IMP		Human	PMID:18692468
Biological Process	GO:1904262	negative regulation of TORC1 signaling	SESN1	IMP		Human	PMID:25263562
Biological Process	GO:1904262	negative regulation of TORC1 signaling	Sesn1	IMP		Mouse	MGI:MGI:5604284|PMID:25259925
Biological Process	GO:0072593	reactive oxygen species metabolic process	SESN1	IMP		Human	PMID:15105503
Biological Process	GO:0051896	regulation of protein kinase B signaling	Sesn1	IDA		Mouse	PMID:22958918

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern