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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Setd2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Setd2
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0043014alpha-tubulin bindingSETD2IDAHumanPMID:27518565
Molecular FunctionGO:0046975histone H3K36 methyltransferase activitySETD2IMPHumanPMID:19141475
Molecular FunctionGO:0046975histone H3K36 methyltransferase activitySETD2IDAHumanPMID:23043551
Molecular FunctionGO:0046975histone H3K36 methyltransferase activitySETD2IMPHumanPMID:23325844
Molecular FunctionGO:0046975histone H3K36 methyltransferase activitySETD2IMPHumanPMID:23622243
Molecular FunctionGO:0046975histone H3K36 methyltransferase activitySETD2IDAHumanPMID:24843002
Molecular FunctionGO:0046975histone H3K36 methyltransferase activitySETD2IDAHumanPMID:26002201
Molecular FunctionGO:0046975histone H3K36 methyltransferase activitySETD2IDAHumanPMID:27474439
Molecular FunctionGO:0046975histone H3K36 methyltransferase activitySETD2IDAHumanPMID:28753426
Molecular FunctionGO:0046975histone H3K36 methyltransferase activitySetd2IMPMouseMGI:MGI:5908786|PMID:25242323
Molecular FunctionGO:0046975histone H3K36 methyltransferase activitySetd2IMPMousePMID:24036311
Molecular FunctionGO:0046975histone H3K36 methyltransferase activitySetd2IMPMGI:MGI:4437211MousePMID:20133625
Molecular FunctionGO:0046975histone H3K36 methyltransferase activitySetd2IMPMousePMID:18157086
Molecular FunctionGO:0046975histone H3K36 methyltransferase activitysetd2IMPZFIN:ZDB-GENO-220329-10ZfishPMID:33088589
Molecular FunctionGO:0046975histone H3K36 methyltransferase activitysetd2IMPZFIN:ZDB-GENO-220329-11ZfishPMID:33088589
Molecular FunctionGO:0005515protein bindingSETD2IPIUniProtKB:P42858HumanPMID:17500595
Molecular FunctionGO:0005515protein bindingSETD2IPIUniProtKB:Q96ST2HumanPMID:19141475
Molecular FunctionGO:0005515protein bindingSETD2IPIUniProtKB:P84022HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingSETD2IPIUniProtKB:P42224HumanPMID:28753426
Molecular FunctionGO:0016279protein-lysine N-methyltransferase activitySETD2IDAHumanPMID:28753426
Cellular ComponentGO:0005694chromosomeSetd2IDAMouseMGI:MGI:3772493|PMID:18157086
Cellular ComponentGO:0005634nucleusSetd2IDAMousePMID:18157086
Cellular ComponentGO:0005634nucleusSetd2IDAMousePMID:11092755
Biological ProcessGO:0001525angiogenesisSetd2IMPMGI:MGI:4437211MousePMID:20133625
Biological ProcessGO:0035441cell migration involved in vasculogenesisSetd2IMPMGI:MGI:4437211MousePMID:20133625
Biological ProcessGO:0060977coronary vasculature morphogenesisSetd2IMPMGI:MGI:4437211MousePMID:20133625
Biological ProcessGO:0051607defense response to virusSETD2IDAHumanPMID:28753426
Biological ProcessGO:0048701embryonic cranial skeleton morphogenesisSetd2IMPMGI:MGI:4437211MousePMID:20133625
Biological ProcessGO:0048568embryonic organ developmentSetd2IMPMGI:MGI:4437211MousePMID:20133625
Biological ProcessGO:0060669embryonic placenta morphogenesisSetd2IMPMGI:MGI:4437211MousePMID:20133625
Biological ProcessGO:0035987endodermal cell differentiationSetd2IMPMouseMGI:MGI:5908786|PMID:25242323
Biological ProcessGO:0030900forebrain developmentSetd2IMPMGI:MGI:4437211MousePMID:20133625
Biological ProcessGO:0097676histone H3-K36 dimethylationSETD2IDAHumanPMID:26002201
Biological ProcessGO:0097198histone H3-K36 trimethylationSETD2IDAHumanPMID:26002201
Biological ProcessGO:0016570histone modificationsetd2IMPZFIN:ZDB-GENO-220329-10ZfishPMID:33088589|ZFIN:ZDB-PUB-201023-8
Biological ProcessGO:0048332mesoderm morphogenesisSetd2IMPMousePMID:20133625
Biological ProcessGO:1902850microtubule cytoskeleton organization involved in mitosisSETD2IDAHumanPMID:27518565
Biological ProcessGO:0006298mismatch repairSETD2IMPHumanPMID:23622243
Biological ProcessGO:0001763morphogenesis of a branching structureSetd2IMPMGI:MGI:4437211MousePMID:20133625
Biological ProcessGO:0001843neural tube closureSetd2IMPMGI:MGI:4437211MousePMID:20133625
Biological ProcessGO:0034728nucleosome organizationSETD2IMPHumanPMID:23325844
Biological ProcessGO:0018023peptidyl-lysine trimethylationSETD2IDAHumanPMID:27518565
Biological ProcessGO:0018023peptidyl-lysine trimethylationSetd2IMPMousePMID:18157086
Biological ProcessGO:0018023peptidyl-lysine trimethylationSetd2IMPMGI:MGI:4437211MousePMID:20133625
Biological ProcessGO:0060039pericardium developmentSetd2IMPMGI:MGI:4437211MousePMID:20133625
Biological ProcessGO:0010508positive regulation of autophagySETD2IDAHumanPMID:36359729
Biological ProcessGO:0032727positive regulation of interferon-alpha productionSETD2IDAHumanPMID:28753426
Biological ProcessGO:0045778positive regulation of ossificationSetd2IMPRatPMID:30746871|RGD:151665130
Biological ProcessGO:0006479protein methylationsetd2IMPZFIN:ZDB-GENO-220329-10ZfishPMID:33088589|ZFIN:ZDB-PUB-201023-8
Biological ProcessGO:0032465regulation of cytokinesisSETD2IDAHumanPMID:27518565
Biological ProcessGO:0010569regulation of double-strand break repair via homologous recombinationSETD2IDAHumanPMID:24843002
Biological ProcessGO:0010468regulation of gene expressionSetd2IMPMGI:MGI:4437211MousePMID:20133625
Biological ProcessGO:0010793regulation of mRNA export from nucleusSETD2IMPHumanPMID:19141475
Biological ProcessGO:1905634regulation of protein localization to chromatinSETD2IDAHumanPMID:24843002
Biological ProcessGO:0043279response to alkaloidSetd2IEPRatPMID:27846294|RGD:151665132
Biological ProcessGO:0010038response to metal ionSetd2IEPRatPMID:30746871|RGD:151665130
Biological ProcessGO:0014070response to organic cyclic compoundSetd2IEPRatPMID:27766425|RGD:151665131
Biological ProcessGO:0034340response to type I interferonSETD2IDAHumanPMID:28753426
Biological ProcessGO:0048864stem cell developmentSetd2IMPMGI:MGI:4437211MousePMID:20133625
Biological ProcessGO:0048863stem cell differentiationSetd2IMPMouseMGI:MGI:5908786|PMID:25242323
Biological ProcessGO:0006368transcription elongation by RNA polymerase IISETD2IMPHumanPMID:23325844
Biological ProcessGO:0001570vasculogenesisSetd2IMPMGI:MGI:4437211MousePMID:20133625

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory