Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SETD5
  • Mouse genes Setd5
  • Rat genes Setd5
  • Zfish genes setd5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Setd5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	Setd5	IMP		Mouse	MGI:MGI:6381850|PMID:31515109
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	Setd5	IDA		Mouse	MGI:MGI:6274969|PMID:22939622
Molecular Function	GO:0005515	protein binding	Setd5	IPI	UniProtKB:Q5XJE5|UniProtKB:Q60974|UniProtKB:Q62018|UniProtKB:Q8JZM7	Mouse	MGI:MGI:5812827|PMID:27864380
Molecular Function	GO:0003714	transcription corepressor activity	Setd5	IDA		Mouse	MGI:MGI:6279386|PMID:30455454
Cellular Component	GO:0000785	chromatin	Setd5	IDA		Mouse	MGI:MGI:5812827|PMID:27864380
Cellular Component	GO:0000791	euchromatin	Setd5	IDA		Mouse	MGI:MGI:6381850|PMID:31515109
Cellular Component	GO:0005654	nucleoplasm	SETD5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Setd5	IDA		Mouse	MGI:MGI:5812827|PMID:27864380
Biological Process	GO:0050890	cognition	Setd5	IMP		Mouse	MGI:MGI:6279386|PMID:30455454
Biological Process	GO:0050890	cognition	Setd5	IMP		Mouse	MGI:MGI:6381850|PMID:31515109
Biological Process	GO:0007507	heart development	setd5	IMP	ZFIN:ZDB-MRPHLNO-151116-9	Zfish	PMID:25533962
Biological Process	GO:0008345	larval locomotory behavior	setd5	IMP	ZFIN:ZDB-MRPHLNO-151116-9	Zfish	PMID:25533962
Biological Process	GO:0016480	negative regulation of transcription by RNA polymerase III	Setd5	IMP		Mouse	MGI:MGI:6279386|PMID:30455454
Biological Process	GO:1902275	regulation of chromatin organization	Setd5	IMP		Mouse	MGI:MGI:6279386|PMID:30455454
Biological Process	GO:1902275	regulation of chromatin organization	Setd5	IMP		Mouse	MGI:MGI:6381850|PMID:31515109
Biological Process	GO:1902275	regulation of chromatin organization	Setd5	IMP		Mouse	MGI:MGI:5812827|PMID:27864380
Biological Process	GO:0032784	regulation of DNA-templated transcription elongation	Setd5	IMP		Mouse	MGI:MGI:6381850|PMID:31515109
Biological Process	GO:0051963	regulation of synapse assembly	Setd5	IMP		Mouse	MGI:MGI:6381850|PMID:31515109

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern