Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SETMAR
  • Mouse genes Setmar
  • Rat genes Setmar
  • Zfish genes setmar
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Setmar

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	SETMAR	IDA		Human	PMID:20521842
Molecular Function	GO:0044547	DNA topoisomerase binding	SETMAR	IPI	UniProtKB:P11388	Human	PMID:18790802
Molecular Function	GO:0044547	DNA topoisomerase binding	SETMAR	IPI	UniProtKB:P11388	Human	PMID:20457750
Molecular Function	GO:0003690	double-stranded DNA binding	SETMAR	IMP		Human	PMID:24573677
Molecular Function	GO:0004519	endonuclease activity	SETMAR	IDA		Human	PMID:20620605
Molecular Function	GO:0004519	endonuclease activity	SETMAR	IDA		Human	PMID:21491884
Molecular Function	GO:0004519	endonuclease activity	SETMAR	IMP		Human	PMID:22231448
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	SETMAR	IDA		Human	PMID:16332963
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	SETMAR	IMP		Human	PMID:21187428
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	SETMAR	IMP		Human	PMID:22231448
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	SETMAR	IDA		Human	PMID:16332963
Molecular Function	GO:0005515	protein binding	SETMAR	IPI	UniProtKB:P11388	Human	PMID:19390626
Molecular Function	GO:0005515	protein binding	SETMAR	IPI	UniProtKB:P12004	Human	PMID:20457750
Molecular Function	GO:0005515	protein binding	SETMAR	IPI	UniProtKB:Q53H47	Human	PMID:20521842
Molecular Function	GO:0005515	protein binding	SETMAR	IPI	UniProtKB:Q8BTF7	Human	PMID:20620605
Molecular Function	GO:0042803	protein homodimerization activity	SETMAR	IPI	UniProtKB:Q53H47	Human	PMID:20521842
Molecular Function	GO:0003697	single-stranded DNA binding	SETMAR	IMP		Human	PMID:24573677
Molecular Function	GO:0000014	single-stranded DNA endodeoxyribonuclease activity	SETMAR	IMP		Human	PMID:24573677
Cellular Component	GO:0000793	condensed chromosome	SETMAR	IDA		Human	PMID:18790802
Cellular Component	GO:0005730	nucleolus	SETMAR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SETMAR	IDA		Human	PMID:22231448
Cellular Component	GO:0035861	site of double-strand break	SETMAR	IDA		Human	PMID:18263876
Cellular Component	GO:0035861	site of double-strand break	SETMAR	IDA		Human	PMID:21187428
Cellular Component	GO:0035861	site of double-strand break	SETMAR	IMP		Human	PMID:22231448
Biological Process	GO:0008283	cell population proliferation	SETMAR	IMP		Human	PMID:20457750
Biological Process	GO:0006308	DNA catabolic process	SETMAR	IDA		Human	PMID:20521842
Biological Process	GO:0006308	DNA catabolic process	SETMAR	IDA		Human	PMID:21491884
Biological Process	GO:0006308	DNA catabolic process	SETMAR	IMP		Human	PMID:24573677
Biological Process	GO:0000729	DNA double-strand break processing	SETMAR	IDA		Human	PMID:21491884
Biological Process	GO:0015074	DNA integration	SETMAR	IMP		Human	PMID:16332963
Biological Process	GO:0015074	DNA integration	SETMAR	IMP		Human	PMID:24573677
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	SETMAR	IDA		Human	PMID:16332963
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	SETMAR	IMP		Human	PMID:18263876
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	SETMAR	IMP		Human	PMID:21187428
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	SETMAR	IMP		Human	PMID:24573677
Biological Process	GO:0044774	mitotic DNA integrity checkpoint signaling	SETMAR	IMP		Human	PMID:18790802
Biological Process	GO:2001251	negative regulation of chromosome organization	SETMAR	IDA		Human	PMID:20620605
Biological Process	GO:0090305	nucleic acid phosphodiester bond hydrolysis	SETMAR	IMP		Human	PMID:22231448
Biological Process	GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	SETMAR	IDA		Human	PMID:18790802
Biological Process	GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	SETMAR	IMP		Human	PMID:20457750
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	SETMAR	IDA		Human	PMID:20620605
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	SETMAR	IDA		Human	PMID:21491884
Biological Process	GO:0031297	replication fork processing	SETMAR	IMP		Human	PMID:20457750
Biological Process	GO:0031297	replication fork processing	SETMAR	IMP		Human	PMID:22231448
Biological Process	GO:0031297	replication fork processing	SETMAR	IMP		Human	PMID:24573677

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern