Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SEZ6
  • Mouse genes Sez6
  • Rat genes Sez6
  • Zfish genes sez6a,sez6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sez6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SEZ6	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Cellular Component	GO:0097440	apical dendrite	Sez6	IDA		Mouse	PMID:18031681
Cellular Component	GO:0043198	dendritic shaft	Sez6	IDA		Mouse	PMID:18031681
Cellular Component	GO:0043197	dendritic spine	Sez6	IDA		Mouse	PMID:18031681
Cellular Component	GO:0005783	endoplasmic reticulum	Sez6	IDA		Mouse	PMID:16814779
Cellular Component	GO:0043025	neuronal cell body	Sez6	IDA		Mouse	PMID:16814779
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Sez6	IDA		Mouse	PMID:19662096
Biological Process	GO:0008344	adult locomotory behavior	Sez6	IGI	MGI:MGI:1935121	Mouse	PMID:16814779
Biological Process	GO:0008344	adult locomotory behavior	Sez6	IGI	MGI:MGI:2385295	Mouse	PMID:16814779
Biological Process	GO:0021680	cerebellar Purkinje cell layer development	Sez6	IGI	MGI:MGI:2385295	Mouse	PMID:16814779
Biological Process	GO:0021680	cerebellar Purkinje cell layer development	Sez6	IGI	MGI:MGI:1935121	Mouse	PMID:16814779
Biological Process	GO:0060079	excitatory postsynaptic potential	Sez6	IMP	MGI:MGI:3777582	Mouse	PMID:18031681
Biological Process	GO:0050773	regulation of dendrite development	Sez6	IMP	MGI:MGI:3777582	Mouse	PMID:18031681
Biological Process	GO:0090036	regulation of protein kinase C signaling	Sez6	IGI	MGI:MGI:2385295	Mouse	PMID:16814779
Biological Process	GO:0090036	regulation of protein kinase C signaling	Sez6	IGI	MGI:MGI:1935121	Mouse	PMID:16814779
Biological Process	GO:0060074	synapse maturation	Sez6	IGI	MGI:MGI:1935121	Mouse	PMID:16814779
Biological Process	GO:0060074	synapse maturation	Sez6	IGI	MGI:MGI:2385295	Mouse	PMID:16814779

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern