Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SF3B1
  • Mouse genes Sf3b1
  • Rat genes Sf3b1
  • Zfish genes sf3b1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sf3b1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Sf3b1	IDA		Mouse	PMID:15741318
Molecular Function	GO:0003682	chromatin binding	Sf3b1	IDA		Mouse	PMID:20153721
Molecular Function	GO:0005515	protein binding	SF3B1	IPI	UniProtKB:Q7Z333	Human	PMID:19515850
Molecular Function	GO:0005515	protein binding	SF3B1	IPI	UniProtKB:Q9Y3B4	Human	PMID:21062891
Molecular Function	GO:0005515	protein binding	SF3B1	IPI	UniProtKB:Q96I25	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	SF3B1	IPI	UniProtKB:Q96T37	Human	PMID:26575292
Molecular Function	GO:0005515	protein binding	SF3B1	IPI	UniProtKB:Q15393	Human	PMID:27720643
Molecular Function	GO:0005515	protein binding	SF3B1	IPI	UniProtKB:Q7RTV0	Human	PMID:27720643
Molecular Function	GO:0005515	protein binding	SF3B1	IPI	UniProtKB:Q9BWJ5	Human	PMID:27720643
Molecular Function	GO:0005515	protein binding	SF3B1	IPI	UniProtKB:Q96I25	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Sf3b1	IPI	PR:Q9CQJ4	Mouse	PMID:15741318
Molecular Function	GO:0005515	protein binding	Sf3b1	IPI	PR:P23798	Mouse	PMID:15741318
Molecular Function	GO:0003723	RNA binding	SF3B1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	SF3B1	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	SF3B1	IDA		Human	PMID:27720643
Molecular Function	GO:1990935	splicing factor binding	SF3B1	IDA		Human	PMID:27720643
Cellular Component	GO:0110016	B-WICH complex	SF3B1	IDA		Human	PMID:16603771
Cellular Component	GO:0071013	catalytic step 2 spliceosome	SF3B1	IDA		Human	PMID:11991638
Cellular Component	GO:0000785	chromatin	Sf3b1	IDA		Mouse	PMID:20153721
Cellular Component	GO:0016363	nuclear matrix	Sf3b1	IDA		Mouse	PMID:20153721
Cellular Component	GO:0016607	nuclear speck	SF3B1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SF3B1	IDA		Human	PMID:18559850
Cellular Component	GO:0005634	nucleus	SF3B1	IDA		Human	PMID:27720643
Cellular Component	GO:0005634	nucleus	SF3B1	IDA		Human	PMID:28541300
Cellular Component	GO:0005634	nucleus	SF3B1	IDA		Human	PMID:28781166
Cellular Component	GO:0005634	nucleus	SF3B1	IDA		Human	PMID:29360106
Cellular Component	GO:0005634	nucleus	Sf3b1	IDA		Mouse	PMID:20153721
Cellular Component	GO:0005634	nucleus	Sf3b1	IDA		Mouse	PMID:23211737
Cellular Component	GO:0005634	nucleus	Sf3b1	IDA		Rat	PMID:14724321|RGD:10054020
Cellular Component	GO:0030532	small nuclear ribonucleoprotein complex	Sf3b1	IDA		Mouse	PMID:20153721
Cellular Component	GO:0034693	U11/U12 snRNP	SF3B1	IDA		Human	PMID:11252167
Cellular Component	GO:0005689	U12-type spliceosomal complex	SF3B1	IDA		Human	PMID:15146077
Cellular Component	GO:0005686	U2 snRNP	SF3B1	IDA		Human	PMID:11252167
Cellular Component	GO:0071005	U2-type precatalytic spliceosome	SF3B1	IDA		Human	PMID:28781166
Cellular Component	GO:0071005	U2-type precatalytic spliceosome	SF3B1	IDA		Human	PMID:29360106
Cellular Component	GO:0005684	U2-type spliceosomal complex	SF3B1	IPI		Human	PMID:27720643
Biological Process	GO:0009952	anterior/posterior pattern specification	Sf3b1	IGI	MGI:MGI:99161	Mouse	PMID:15741318
Biological Process	GO:0009952	anterior/posterior pattern specification	Sf3b1	IGI	MGI:MGI:96995	Mouse	PMID:15741318
Biological Process	GO:0001825	blastocyst formation	Sf3b1	IMP		Mouse	PMID:27869233
Biological Process	GO:0001825	blastocyst formation	Sf3b1	IMP		Mouse	PMID:23211737
Biological Process	GO:0060216	definitive hemopoiesis	sf3b1	IMP	ZFIN:ZDB-GENO-161117-16	Zfish	PMID:27260753
Biological Process	GO:0060218	hematopoietic stem cell differentiation	sf3b1	IMP	ZFIN:ZDB-MRPHLNO-121004-2	Zfish	PMID:27260753
Biological Process	GO:0060218	hematopoietic stem cell differentiation	sf3b1	IMP	ZFIN:ZDB-GENO-161117-16	Zfish	PMID:27260753
Biological Process	GO:0030318	melanocyte differentiation	sf3b1	IGI	ZFIN:ZDB-GENE-011207-1,ZFIN:ZDB-GENO-121004-5	Zfish	PMID:22562198
Biological Process	GO:0030318	melanocyte differentiation	sf3b1	IMP	ZFIN:ZDB-GENO-121004-5	Zfish	PMID:22562198
Biological Process	GO:0030318	melanocyte differentiation	sf3b1	IGI	ZFIN:ZDB-GENE-011212-6,ZFIN:ZDB-GENO-121004-5	Zfish	PMID:22562198
Biological Process	GO:0000398	mRNA splicing, via spliceosome	SF3B1	IDA		Human	PMID:11252167
Biological Process	GO:0000398	mRNA splicing, via spliceosome	SF3B1	IDA		Human	PMID:27720643
Biological Process	GO:0000398	mRNA splicing, via spliceosome	SF3B1	IDA		Human	PMID:28781166
Biological Process	GO:0000398	mRNA splicing, via spliceosome	SF3B1	IDA		Human	PMID:29360106
Biological Process	GO:0000398	mRNA splicing, via spliceosome	Sf3b1	IMP		Mouse	PMID:23211737
Biological Process	GO:0061515	myeloid cell development	sf3b1	IMP	ZFIN:ZDB-GENO-161117-16	Zfish	PMID:27260753
Biological Process	GO:0014032	neural crest cell development	sf3b1	IMP	ZFIN:ZDB-GENO-121004-5	Zfish	PMID:22562198
Biological Process	GO:0045945	positive regulation of transcription by RNA polymerase III	SF3B1	IDA		Human	PMID:16603771
Biological Process	GO:0042981	regulation of apoptotic process	sf3b1	IGI	ZFIN:ZDB-GENE-051012-1,ZFIN:ZDB-GENO-121004-5	Zfish	PMID:22562198

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern