Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SFTPA1,SFTPA2
  • Mouse genes Sftpa1
  • Rat genes Sftpa1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sftpa1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SFTPA2	IPI	UniProtKB:P62166	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SFTPA2	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SFTPA1	IPI	UniProtKB:Q9UGM3	Human	PMID:10101009
Molecular Function	GO:0005515	protein binding	SFTPA1	IPI	UniProtKB:P75409	Human	PMID:15845487
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Sftpa1	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0031410	cytoplasmic vesicle	Sftpa1	IDA		Rat	PMID:16187065|RGD:4143471
Cellular Component	GO:0005615	extracellular space	Sftpa1	IDA		Rat	PMID:11472975|RGD:4143429
Cellular Component	GO:0005771	multivesicular body	Sftpa1	IDA		Rat	PMID:16187065|RGD:4143471
Cellular Component	GO:0005791	rough endoplasmic reticulum	Sftpa1	IDA		Rat	PMID:16187065|RGD:4143471
Biological Process	GO:0071260	cellular response to mechanical stimulus	Sftpa1	IEP		Rat	PMID:12600831|RGD:4143475
Biological Process	GO:0071732	cellular response to nitric oxide	Sftpa1	IEP		Rat	PMID:15640287|RGD:4143401
Biological Process	GO:0007623	circadian rhythm	Sftpa1	IEP		Rat	PMID:12872443|RGD:4143473
Biological Process	GO:0008228	opsonization	SFTPA1	IMP		Human	PMID:21123169
Biological Process	GO:0050766	positive regulation of phagocytosis	Sftpa1	IDA		Rat	PMID:15187139|RGD:4144050
Biological Process	GO:0070849	response to epidermal growth factor	Sftpa1	IEP		Rat	PMID:19781387|RGD:4143468
Biological Process	GO:0051384	response to glucocorticoid	Sftpa1	IEP		Rat	PMID:2015097|RGD:4143484
Biological Process	GO:0009725	response to hormone	Sftpa1	IEP		Rat	PMID:9779374|RGD:4143480
Biological Process	GO:0055093	response to hyperoxia	Sftpa1	IEP		Rat	PMID:11472975|RGD:4143429
Biological Process	GO:0001666	response to hypoxia	Sftpa1	IEP		Rat	PMID:14756961|RGD:4143406
Biological Process	GO:0070741	response to interleukin-6	Sftpa1	IEP		Rat	PMID:11000512|RGD:4144154
Biological Process	GO:0032496	response to lipopolysaccharide	Sftpa1	IEP		Rat	PMID:11000512|RGD:4144154
Biological Process	GO:0032526	response to retinoic acid	Sftpa1	IEP		Rat	PMID:9505268|RGD:4143481
Biological Process	GO:0033189	response to vitamin A	Sftpa1	IEP		Rat	PMID:10385596|RGD:4144157

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern