Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SFTPB
  • Mouse genes Sftpb
  • Rat genes Sftpb
  • Zfish genes sftpba,sftpbb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sftpb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SFTPB	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Cellular Component	GO:0097208	alveolar lamellar body	Sftpb	IDA		Rat	PMID:16187065|RGD:4143471
Cellular Component	GO:0097208	alveolar lamellar body	Sftpb	IDA		Rat	PMID:2475034|RGD:151667440
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Sftpb	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0005737	cytoplasm	Sftpb	IDA		Mouse	PMID:8813084
Cellular Component	GO:0005737	cytoplasm	Sftpb	IDA		Mouse	PMID:24191021
Cellular Component	GO:0005615	extracellular space	Sftpb	IDA		Rat	PMID:11704537|RGD:628506
Cellular Component	GO:0005771	multivesicular body	Sftpb	IDA		Rat	PMID:16187065|RGD:4143471
Biological Process	GO:0071260	cellular response to mechanical stimulus	Sftpb	IEP		Rat	PMID:12600831|RGD:4143475
Biological Process	GO:0071732	cellular response to nitric oxide	Sftpb	IEP		Rat	PMID:15640287|RGD:4143401
Biological Process	GO:0007623	circadian rhythm	Sftpb	IEP		Rat	PMID:12872443|RGD:4143473
Biological Process	GO:0051591	response to cAMP	Sftpb	IEP		Rat	PMID:1850607|RGD:151667426
Biological Process	GO:0071548	response to dexamethasone	Sftpb	IEP		Rat	PMID:1850607|RGD:151667426
Biological Process	GO:0070849	response to epidermal growth factor	Sftpb	IEP		Rat	PMID:19781387|RGD:4143468
Biological Process	GO:0051384	response to glucocorticoid	Sftpb	IEP		Rat	PMID:10830305|RGD:4143434
Biological Process	GO:0009749	response to glucose	Sftpb	IEP		Rat	PMID:10027080|RGD:4143477
Biological Process	GO:0070848	response to growth factor	Sftpb	IEP		Rat	PMID:17267143|RGD:4143467
Biological Process	GO:0055093	response to hyperoxia	Sftpb	IEP		Rat	PMID:11472975|RGD:4143429
Biological Process	GO:0001666	response to hypoxia	Sftpb	IEP		Rat	PMID:14756961|RGD:4143406
Biological Process	GO:0070741	response to interleukin-6	Sftpb	IEP		Rat	PMID:11000512|RGD:4144154
Biological Process	GO:0044321	response to leptin	Sftpb	IEP		Rat	PMID:11839533|RGD:151667444
Biological Process	GO:0032496	response to lipopolysaccharide	Sftpb	IEP		Rat	PMID:11000512|RGD:4144154
Biological Process	GO:0032496	response to lipopolysaccharide	Sftpb	IEP		Rat	PMID:27338059|RGD:151667427
Biological Process	GO:1904016	response to Thyroglobulin triiodothyronine	Sftpb	IEP		Rat	PMID:1850607|RGD:151667426
Biological Process	GO:0033189	response to vitamin A	Sftpb	IEP		Rat	PMID:10385596|RGD:4144157

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern