Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SFTPD
  • Mouse genes Sftpd
  • Rat genes Sftpd
  • Zfish genes hbl4,mbl2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sftpd

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Sftpd	IPI	UniProtKB:P50404	Mouse	MGI:MGI:3831640|PMID:19007302
Molecular Function	GO:0042802	identical protein binding	Sftpd	IPI	UniProtKB:P35248	Rat	PMID:19007302|RGD:13432249
Molecular Function	GO:0042802	identical protein binding	Sftpd	IDA		Rat	PMID:19017984|RGD:4143523
Molecular Function	GO:0001530	lipopolysaccharide binding	Sftpd	IDA		Rat	PMID:18092821|RGD:4143524
Molecular Function	GO:0048029	monosaccharide binding	Sftpd	IDA		Rat	PMID:18092821|RGD:4143524
Molecular Function	GO:0005515	protein binding	SFTPD	IPI	UniProtKB:Q60997	Human	PMID:12884308
Molecular Function	GO:0005515	protein binding	SFTPD	IPI	UniProtKB:O00322	Human	PMID:28228557
Molecular Function	GO:0005515	protein binding	SFTPD	IPI	UniProtKB:P0DTC2	Human	PMID:33784482
Molecular Function	GO:0005515	protein binding	SFTPD	IPI	UniProtKB:Q9BYF1	Human	PMID:33784482
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Sftpd	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0005737	cytoplasm	Sftpd	IDA		Mouse	PMID:21408140
Cellular Component	GO:0031410	cytoplasmic vesicle	Sftpd	IDA		Rat	PMID:16187065|RGD:4143471
Cellular Component	GO:0005615	extracellular space	Sftpd	IDA		Rat	PMID:11472975|RGD:4143429
Cellular Component	GO:0005771	multivesicular body	Sftpd	IDA		Rat	PMID:16187065|RGD:4143471
Cellular Component	GO:0005791	rough endoplasmic reticulum	Sftpd	IDA		Rat	PMID:16187065|RGD:4143471
Biological Process	GO:0043152	induction of bacterial agglutination	SFTPD	IMP		Human	PMID:28228557
Biological Process	GO:0048286	lung alveolus development	SFTPD	IMP		Human	PMID:9751757
Biological Process	GO:0052403	negative regulation by host of symbiont catalytic activity	SFTPD	IDA		Human	PMID:28228557
Biological Process	GO:0032703	negative regulation of interleukin-2 production	Sftpd	IDA		Rat	PMID:9794387|RGD:4144057
Biological Process	GO:0050765	negative regulation of phagocytosis	Sftpd	IDA		Rat	PMID:12654779|RGD:4144053
Biological Process	GO:0042130	negative regulation of T cell proliferation	Sftpd	IDA		Rat	PMID:9794387|RGD:4144057
Biological Process	GO:0008228	opsonization	Sftpd	IDA		Rat	PMID:19017984|RGD:4143523
Biological Process	GO:0050766	positive regulation of phagocytosis	Sftpd	IDA		Rat	PMID:15591410|RGD:4144046
Biological Process	GO:1905226	regulation of adhesion of symbiont to host epithelial cell	SFTPD	IDA		Human	PMID:28228557
Biological Process	GO:0031960	response to corticosteroid	Sftpd	IEP		Rat	PMID:19380841|RGD:4143521
Biological Process	GO:0051384	response to glucocorticoid	Sftpd	IEP		Rat	PMID:8292379|RGD:4143482
Biological Process	GO:0070848	response to growth factor	Sftpd	IEP		Rat	PMID:11076805|RGD:4144153
Biological Process	GO:0055093	response to hyperoxia	Sftpd	IEP		Rat	PMID:11472975|RGD:4143429
Biological Process	GO:0043129	surfactant homeostasis	SFTPD	IMP		Human	PMID:9751757
Biological Process	GO:0043129	surfactant homeostasis	Sftpd	IMP		Rat	PMID:10666121|RGD:4144056
Biological Process	GO:0043129	surfactant homeostasis	Sftpd	IDA		Rat	PMID:9201966|RGD:4144058

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern