Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SGMS1
  • Mouse genes Sgms1
  • Rat genes Sgms1
  • Zfish genes sgms1a,sgms1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sgms1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047493	ceramide cholinephosphotransferase activity	SGMS1	IDA		Human	PMID:14685263
Molecular Function	GO:0002950	ceramide phosphoethanolamine synthase activity	SGMS1	IDA		Human	PMID:25605874
Molecular Function	GO:0002950	ceramide phosphoethanolamine synthase activity	Sgms1	IMP		Mouse	PMID:25605874
Molecular Function	GO:0033188	sphingomyelin synthase activity	SGMS1	IMP		Human	PMID:14976195
Molecular Function	GO:0033188	sphingomyelin synthase activity	SGMS1	IDA		Human	PMID:17982138
Molecular Function	GO:0033188	sphingomyelin synthase activity	Sgms1	IDA		Mouse	MGI:MGI:6221394|PMID:27892528
Molecular Function	GO:0033188	sphingomyelin synthase activity	Sgms1	IMP		Mouse	MGI:MGI:3715076|PMID:14976195
Cellular Component	GO:0000139	Golgi membrane	SGMS1	IDA		Human	PMID:14685263
Cellular Component	GO:0000138	Golgi trans cisterna	SGMS1	IDA		Human	PMID:14685263
Cellular Component	GO:0016020	membrane	SGMS1	HDA		Human	PMID:19946888
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Sgms1	IEP		Rat	PMID:12353928|RGD:1302423
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Sgms1	IEP		Rat	PMID:12353928|RGD:1302423
Biological Process	GO:0046513	ceramide biosynthetic process	SGMS1	IDA		Human	PMID:25605874
Biological Process	GO:0046513	ceramide biosynthetic process	Sgms1	IMP		Mouse	PMID:25605874
Biological Process	GO:0006954	inflammatory response	Sgms1	IDA		Rat	PMID:12353928|RGD:1302423
Biological Process	GO:0010628	positive regulation of gene expression	Sgms1	IDA		Rat	PMID:12353928|RGD:1302423
Biological Process	GO:0006686	sphingomyelin biosynthetic process	SGMS1	IDA		Human	PMID:14685263
Biological Process	GO:0006686	sphingomyelin biosynthetic process	SGMS1	IDA		Human	PMID:14976195
Biological Process	GO:0006686	sphingomyelin biosynthetic process	SGMS1	IDA		Human	PMID:17982138
Biological Process	GO:0006686	sphingomyelin biosynthetic process	Sgms1	IMP		Mouse	MGI:MGI:6221394|PMID:27892528

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern