Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SH3BP4
  • Mouse genes Sh3bp4
  • Rat genes Sh3bp4
  • Zfish genes sh3bp4,sh3bp4a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sh3bp4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005092	GDP-dissociation inhibitor activity	SH3BP4	IMP		Human	PMID:22575674
Molecular Function	GO:0042802	identical protein binding	SH3BP4	IPI	UniProtKB:Q9P0V3	Human	PMID:16325581
Molecular Function	GO:0005515	protein binding	SH3BP4	IPI	UniProtKB:P02786	Human	PMID:16325581
Molecular Function	GO:0005515	protein binding	SH3BP4	IPI	UniProtKB:P39052	Human	PMID:16325581
Molecular Function	GO:0005515	protein binding	SH3BP4	IPI	UniProtKB:P42566	Human	PMID:16325581
Molecular Function	GO:0005515	protein binding	SH3BP4	IPI	UniProtKB:P50570	Human	PMID:16325581
Molecular Function	GO:0005515	protein binding	SH3BP4	IPI	UniProtKB:Q9HB21	Human	PMID:18654987
Molecular Function	GO:0005515	protein binding	SH3BP4	IPI	UniProtKB:Q9ULV3	Human	PMID:18654987
Molecular Function	GO:0005515	protein binding	SH3BP4	IPI	UniProtKB:Q98325	Human	PMID:30842330
Molecular Function	GO:0005515	protein binding	SH3BP4	IPI	UniProtKB:P42566	Human	PMID:35044719
Molecular Function	GO:0031267	small GTPase binding	SH3BP4	IPI	UniProtKB:Q5VZM2	Human	PMID:22575674
Molecular Function	GO:0031267	small GTPase binding	SH3BP4	IPI	UniProtKB:Q7L523	Human	PMID:22575674
Molecular Function	GO:0031267	small GTPase binding	SH3BP4	IPI	UniProtKB:Q9HB90	Human	PMID:22575674
Molecular Function	GO:0031267	small GTPase binding	SH3BP4	IPI	UniProtKB:Q9NQL2	Human	PMID:22575674
Cellular Component	GO:0005737	cytoplasm	SH3BP4	IDA		Human	PMID:22575674
Cellular Component	GO:0070062	extracellular exosome	SH3BP4	HDA		Human	PMID:19056867
Biological Process	GO:0071230	cellular response to amino acid stimulus	SH3BP4	IMP		Human	PMID:22575674
Biological Process	GO:0030308	negative regulation of cell growth	SH3BP4	IMP		Human	PMID:22575674
Biological Process	GO:0008285	negative regulation of cell population proliferation	SH3BP4	IMP		Human	PMID:22575674
Biological Process	GO:0034260	negative regulation of GTPase activity	SH3BP4	IDA		Human	PMID:22575674
Biological Process	GO:0032007	negative regulation of TOR signaling	SH3BP4	IMP		Human	PMID:22575674
Biological Process	GO:0010508	positive regulation of autophagy	SH3BP4	IMP		Human	PMID:22575674
Biological Process	GO:0061462	protein localization to lysosome	SH3BP4	IMP		Human	PMID:22575674
Biological Process	GO:0050790	regulation of catalytic activity	SH3BP4	IMP		Human	PMID:22575674

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern