Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Sh3gl2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SH3GL2
- Mouse genes Sh3gl2
- Rat genes Sh3gl2
- Zfish genes sh3gl2a,sh3gl2b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sh3gl2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	SH3GL2	IPI	UniProtKB:Q99962	Human	PMID:16115810
Molecular Function	GO:0042802	identical protein binding	SH3GL2	IPI	UniProtKB:Q99962	Human	PMID:20404169
Molecular Function	GO:0042802	identical protein binding	SH3GL2	IPI	UniProtKB:Q99962	Human	PMID:25517094
Molecular Function	GO:0042802	identical protein binding	Sh3gl2	IPI	UniProtKB:Q62420	Mouse	MGI:MGI:5926309\|PMID:18940612
Molecular Function	GO:0042802	identical protein binding	Sh3gl2	IPI	RGD:620276	Rat	PMID:24568626\|RGD:13464354
Molecular Function	GO:0008289	lipid binding	Sh3gl2	IDA		Rat	PMID:11604418\|RGD:13464123
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:O35674	Human	PMID:10531379
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:O88839	Human	PMID:10531379
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q13443	Human	PMID:10531379
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q13444	Human	PMID:10531379
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q61072	Human	PMID:10531379
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q62910	Human	PMID:10764144
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q9BQI5	Human	PMID:15919751
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q99700	Human	PMID:16115810
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q99961	Human	PMID:16115810
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q99963	Human	PMID:16115810
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q96B97	Human	PMID:16164598
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:P50402	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:P50570	Human	PMID:16696976
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q99700	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q9H3S7	Human	PMID:17174262
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:P50570	Human	PMID:17257598
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q62910	Human	PMID:17257598
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q99700	Human	PMID:18602463
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q8WUM4	Human	PMID:18641129
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q96B97	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q99961	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q99963	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q5S007	Human	PMID:22998870
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q70E73	Human	PMID:24076656
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:P00533	Human	PMID:24854121
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q5S007	Human	PMID:25501810
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q70E73	Human	PMID:25517094
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:Q99961	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SH3GL2	IPI	UniProtKB:O60241	Human	PMID:28891236
Molecular Function	GO:0005515	protein binding	Sh3gl2	IPI	UniProtKB:Q8BHE4	Mouse	MGI:MGI:5825424\|PMID:21849472
Molecular Function	GO:0005515	protein binding	Sh3gl2	IPI	UniProtKB:Q8K382	Mouse	MGI:MGI:3694831\|PMID:17182770
Molecular Function	GO:0005515	protein binding	Sh3gl2	IPI	PR:P39053	Mouse	PMID:19481455
Molecular Function	GO:0005515	protein binding	Sh3gl2	IPI	PR:Q9WVS6	Mouse	PMID:20064468
Molecular Function	GO:0005515	protein binding	Sh3gl2	IPI	PR:Q99J31	Mouse	PMID:19481455
Molecular Function	GO:0005515	protein binding	Sh3gl2	IPI	PR:Q8CHC4	Mouse	PMID:18093523
Molecular Function	GO:0005515	protein binding	Sh3gl2	IPI	UniProtKB:Q925Q9	Mouse	PMID:16164598
Molecular Function	GO:0005515	protein binding	Sh3gl2	IPI	RGD:728898	Rat	PMID:11498538\|RGD:628465
Molecular Function	GO:0005515	protein binding	Sh3gl2	IPI	RGD:69434	Rat	PMID:11518713\|RGD:13464360
Molecular Function	GO:0005515	protein binding	Sh3gl2	IPI	RGD:708456	Rat	PMID:11518713\|RGD:13464360
Molecular Function	GO:0005515	protein binding	Sh3gl2	IPI	RGD:620101	Rat	PMID:16815333\|RGD:13504741
Molecular Function	GO:0005515	protein binding	Sh3gl2	IPI	UniProtKB:P21575	Rat	PMID:17437541\|RGD:8554440
Molecular Function	GO:0005515	protein binding	Sh3gl2	IPI	RGD:71096	Rat	PMID:22961472\|RGD:13464121
Molecular Function	GO:0005515	protein binding	Sh3gl2	IPI	UniProtKB:O43295	Rat	PMID:25819436\|RGD:10047166
Molecular Function	GO:0005515	protein binding	Sh3gl2	IPI	RGD:69434	Rat	PMID:9238017\|RGD:633918
Molecular Function	GO:0005515	protein binding	Sh3gl2	IPI	UniProtKB:P21575	Rat	PMID:9238017\|RGD:633918
Molecular Function	GO:0005515	protein binding	Sh3gl2	IPI	UniProtKB:Q62910	Rat	PMID:9238017\|RGD:633918
Molecular Function	GO:0019901	protein kinase binding	Sh3gl2	IPI	RGD:621280	Rat	PMID:11384986\|RGD:727317
Molecular Function	GO:0044325	transmembrane transporter binding	Sh3gl2	IPI	RGD:1347795	Rat	PMID:22961472\|RGD:13464121
Cellular Component	GO:0097441	basal dendrite	Sh3gl2	IDA		Rat	PMID:14751282\|RGD:13464355
Cellular Component	GO:0005829	cytosol	Sh3gl2	IDA		Rat	PMID:9079704\|RGD:13504743
Cellular Component	GO:0005769	early endosome	Sh3gl2	IDA		Mouse	MGI:MGI:5825424\|PMID:21849472
Cellular Component	GO:0098978	glutamatergic synapse	Sh3gl2	IDA		Mouse	PMID:25771685
Cellular Component	GO:0098978	glutamatergic synapse	Sh3gl2	IEP		Mouse	PMID:25771685
Cellular Component	GO:0098978	glutamatergic synapse	Sh3gl2	IMP		Mouse	PMID:25771685
Cellular Component	GO:0098978	glutamatergic synapse	Sh3gl2	IDA		Rat	PMID:17088211\|RGD:10047209
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Sh3gl2	IDA		Rat	PMID:11518713\|RGD:13464360
Cellular Component	GO:0043025	neuronal cell body	Sh3gl2	IDA		Rat	PMID:14751282\|RGD:13464355
Cellular Component	GO:0048471	perinuclear region of cytoplasm	SH3GL2	IMP		Human	PMID:24854121
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Sh3gl2	IDA		Rat	PMID:14751282\|RGD:13464355
Cellular Component	GO:0098684	photoreceptor ribbon synapse	Sh3gl2	IDA		Mouse	PMID:23785143
Cellular Component	GO:0098794	postsynapse	Sh3gl2	IDA		Mouse	PMID:25771685
Cellular Component	GO:0098794	postsynapse	Sh3gl2	IEP		Mouse	PMID:25771685
Cellular Component	GO:0098793	presynapse	Sh3gl2	IDA		Rat	PMID:11518713\|RGD:13464360
Cellular Component	GO:0099523	presynaptic cytosol	Sh3gl2	IDA		Mouse	PMID:23785143
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Sh3gl2	IDA		Rat	PMID:11518713\|RGD:13464360
Cellular Component	GO:0045202	synapse	Sh3gl2	IDA		Rat	PMID:11518713\|RGD:13464360
Cellular Component	GO:0045202	synapse	Sh3gl2	IDA		Rat	PMID:16710756\|RGD:13504738
Cellular Component	GO:0030672	synaptic vesicle membrane	Sh3gl2	IDA		Rat	PMID:17088211\|RGD:10047209
Biological Process	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	Sh3gl2	IMP		Mouse	MGI:MGI:5825424\|PMID:21849472
Biological Process	GO:0097484	dendrite extension	Sh3gl2	IMP		Mouse	MGI:MGI:5825424\|PMID:21849472
Biological Process	GO:0060988	lipid tube assembly	Sh3gl2	IDA		Rat	PMID:20484046\|RGD:13464358
Biological Process	GO:0097753	membrane bending	Sh3gl2	IMP		Rat	PMID:16763559\|RGD:13464122
Biological Process	GO:0097749	membrane tubulation	Sh3gl2	IMP		Rat	PMID:11604418\|RGD:13464123
Biological Process	GO:0097749	membrane tubulation	Sh3gl2	IDA		Rat	PMID:20484046\|RGD:13464358
Biological Process	GO:1905604	negative regulation of blood-brain barrier permeability	SH3GL2	IMP		Human	PMID:24854121
Biological Process	GO:0010629	negative regulation of gene expression	SH3GL2	IMP		Human	PMID:24854121
Biological Process	GO:0001933	negative regulation of protein phosphorylation	SH3GL2	IMP		Human	PMID:24854121
Biological Process	GO:0031175	neuron projection development	Sh3gl2	IMP		Mouse	MGI:MGI:5825424\|PMID:21849472
Biological Process	GO:1903527	positive regulation of membrane tubulation	Sh3gl2	IMP		Rat	PMID:24778241\|RGD:13464356
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Sh3gl2	IDA		Mouse	PMID:25771685
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Sh3gl2	IMP		Mouse	PMID:25771685
Biological Process	GO:2000369	regulation of clathrin-dependent endocytosis	Sh3gl2	IMP		Rat	PMID:15066995\|RGD:13504745
Biological Process	GO:0002090	regulation of receptor internalization	Sh3gl2	IDA		Mouse	PMID:16164598
Biological Process	GO:0048488	synaptic vesicle endocytosis	Sh3gl2	IGI	MGI:MGI:2151070	Mouse	PMID:19481455
Biological Process	GO:0048488	synaptic vesicle endocytosis	Sh3gl2	IDA		Rat	PMID:22099461\|RGD:13702445
Biological Process	GO:0048488	synaptic vesicle endocytosis	Sh3gl2	IMP		Rat	PMID:22099461\|RGD:13702445
Biological Process	GO:0016191	synaptic vesicle uncoating	Sh3gl2	IGI	UniProtKB:Q62419,UniProtKB:Q62421	Mouse	MGI:MGI:5300660\|PMID:22099461
Biological Process	GO:0099050	vesicle scission	Sh3gl2	IDA		Rat	PMID:11604418\|RGD:13464123

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.