Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SH3GL3
  • Mouse genes Sh3gl3
  • Rat genes Sh3gl3
  • Zfish genes sh3gl3a,sh3gl3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sh3gl3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	SH3GL3	IPI	UniProtKB:Q99963	Human	PMID:16115810
Molecular Function	GO:0042802	identical protein binding	SH3GL3	IPI	UniProtKB:Q99963	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	SH3GL3	IPI	UniProtKB:P42858	Human	PMID:15383276
Molecular Function	GO:0005515	protein binding	SH3GL3	IPI	UniProtKB:Q9BQI5	Human	PMID:15919751
Molecular Function	GO:0005515	protein binding	SH3GL3	IPI	UniProtKB:P42858	Human	PMID:16115810
Molecular Function	GO:0005515	protein binding	SH3GL3	IPI	UniProtKB:Q99700	Human	PMID:16115810
Molecular Function	GO:0005515	protein binding	SH3GL3	IPI	UniProtKB:Q99961	Human	PMID:16115810
Molecular Function	GO:0005515	protein binding	SH3GL3	IPI	UniProtKB:Q99962	Human	PMID:16115810
Molecular Function	GO:0005515	protein binding	SH3GL3	IPI	UniProtKB:Q99961	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	SH3GL3	IPI	UniProtKB:Q99700	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	SH3GL3	IPI	UniProtKB:P42858	Human	PMID:17161366
Molecular Function	GO:0005515	protein binding	SH3GL3	IPI	UniProtKB:Q99700	Human	PMID:18602463
Molecular Function	GO:0005515	protein binding	SH3GL3	IPI	UniProtKB:Q99961	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	SH3GL3	IPI	UniProtKB:Q99962	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	SH3GL3	IPI	UniProtKB:Q70E73	Human	PMID:24076656
Molecular Function	GO:0005515	protein binding	Sh3gl3	IPI	PR:Q8K4B0	Mouse	PMID:15978591
Molecular Function	GO:0005515	protein binding	Sh3gl3	IPI	RGD:620101	Rat	PMID:16815333|RGD:13504741
Molecular Function	GO:0005515	protein binding	Sh3gl3	IPI	RGD:1347795	Rat	PMID:22961472|RGD:13464121
Molecular Function	GO:0005515	protein binding	Sh3gl3	IPI	RGD:69434|RGD:71096	Rat	PMID:9238017|RGD:633918
Molecular Function	GO:0005515	protein binding	Sh3gl3	IPI	UniProtKB:P21575	Rat	PMID:9238017|RGD:633918
Molecular Function	GO:0005515	protein binding	Sh3gl3	IPI	UniProtKB:Q62910	Rat	PMID:9238017|RGD:633918
Cellular Component	GO:0001669	acrosomal vesicle	Sh3gl3	IDA		Rat	PMID:15225413|RGD:13504859
Cellular Component	GO:0005737	cytoplasm	Sh3gl3	IDA		Mouse	PMID:15978591
Cellular Component	GO:0005769	early endosome	Sh3gl3	IDA		Rat	PMID:17088211|RGD:10047209
Cellular Component	GO:0098978	glutamatergic synapse	Sh3gl3	IDA		Rat	PMID:17088211|RGD:10047209
Cellular Component	GO:0098978	glutamatergic synapse	Sh3gl3	IMP		Rat	PMID:17088211|RGD:10047209
Cellular Component	GO:0099092	postsynaptic density, intracellular component	Sh3gl3	IDA		Rat	PMID:17088211|RGD:10047209
Cellular Component	GO:0099092	postsynaptic density, intracellular component	Sh3gl3	IMP		Rat	PMID:17088211|RGD:10047209
Cellular Component	GO:0098845	postsynaptic endosome	Sh3gl3	IDA		Rat	PMID:17088211|RGD:10047209
Cellular Component	GO:0098845	postsynaptic endosome	Sh3gl3	IMP		Rat	PMID:17088211|RGD:10047209
Cellular Component	GO:0098793	presynapse	Sh3gl3	IDA		Rat	PMID:15066995|RGD:13504745
Cellular Component	GO:0045202	synapse	Sh3gl3	IDA		Rat	PMID:16710756|RGD:13504738
Biological Process	GO:0072554	blood vessel lumenization	sh3gl3b	IGI	ZFIN:ZDB-GENE-091204-186	Zfish	PMID:23539215
Biological Process	GO:0072554	blood vessel lumenization	sh3gl3b	IMP	ZFIN:ZDB-MRPHLNO-090521-2	Zfish	PMID:23539215
Biological Process	GO:0072554	blood vessel lumenization	sh3gl3b	IGI	ZFIN:ZDB-GENE-030918-1	Zfish	PMID:23539215
Biological Process	GO:0048514	blood vessel morphogenesis	sh3gl3b	IMP	ZFIN:ZDB-MRPHLNO-090521-2	Zfish	PMID:19308258
Biological Process	GO:1900186	negative regulation of clathrin-dependent endocytosis	Sh3gl3	IMP		Rat	PMID:15066995|RGD:13504745
Biological Process	GO:0045666	positive regulation of neuron differentiation	Sh3gl3	IMP		Rat	PMID:15066995|RGD:13504745
Biological Process	GO:2000369	regulation of clathrin-dependent endocytosis	Sh3gl3	IMP		Rat	PMID:15066995|RGD:13504745
Biological Process	GO:0016191	synaptic vesicle uncoating	Sh3gl3	IGI	UniProtKB:Q62419,UniProtKB:Q62420	Mouse	MGI:MGI:5300660|PMID:22099461

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern