Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SH3PXD2A
  • Mouse genes Sh3pxd2a
  • Rat genes Sh3pxd2a
  • Zfish genes sh3pxd2aa,sh3pxd2ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sh3pxd2a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035091	phosphatidylinositol binding	Sh3pxd2a	IMP		Mouse	MGI:MGI:6158822|PMID:12615925
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	Sh3pxd2a	IMP		Mouse	MGI:MGI:6158822|PMID:12615925
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	Sh3pxd2a	IMP		Mouse	MGI:MGI:6158822|PMID:12615925
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	Sh3pxd2a	IMP		Mouse	MGI:MGI:6158822|PMID:12615925
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	Sh3pxd2a	IMP		Mouse	MGI:MGI:6158822|PMID:12615925
Molecular Function	GO:0010314	phosphatidylinositol-5-phosphate binding	Sh3pxd2a	IMP		Mouse	MGI:MGI:6158822|PMID:12615925
Molecular Function	GO:0002020	protease binding	Sh3pxd2a	IPI	UniProtKB:O35674	Mouse	MGI:MGI:6158822|PMID:12615925
Molecular Function	GO:0005515	protein binding	SH3PXD2A	IPI	UniProtKB:Q13444	Human	PMID:16374509
Molecular Function	GO:0005515	protein binding	SH3PXD2A	IPI	UniProtKB:Q86UR1	Human	PMID:19755710
Molecular Function	GO:0005515	protein binding	SH3PXD2A	IPI	UniProtKB:Q86UR1	Human	PMID:20609497
Molecular Function	GO:0005515	protein binding	SH3PXD2A	IPI	UniProtKB:Q13444	Human	PMID:25825872
Molecular Function	GO:0005515	protein binding	Sh3pxd2a	IPI	UniProtKB:Q61462	Mouse	MGI:MGI:5285168|PMID:19755709
Cellular Component	GO:0005737	cytoplasm	Sh3pxd2a	IDA		Mouse	MGI:MGI:6158822|PMID:12615925
Cellular Component	GO:0002102	podosome	SH3PXD2A	IDA		Human	PMID:18417249
Cellular Component	GO:0002102	podosome	Sh3pxd2a	IDA		Mouse	MGI:MGI:6158822|PMID:12615925
Biological Process	GO:0001701	in utero embryonic development	Sh3pxd2a	IMP	MGI:MGI:5636944	Mouse	PMID:27996060
Biological Process	GO:0001755	neural crest cell migration	sh3pxd2aa	IMP	ZFIN:ZDB-MRPHLNO-110816-1	Zfish	PMID:21799874
Biological Process	GO:0072675	osteoclast fusion	SH3PXD2A	IMP		Human	PMID:22584907
Biological Process	GO:0048920	posterior lateral line neuromast primordium migration	sh3pxd2aa	IMP	ZFIN:ZDB-CRISPR-151022-13,ZFIN:ZDB-CRISPR-151022-14	Zfish	PMID:25810455
Biological Process	GO:0072593	reactive oxygen species metabolic process	Sh3pxd2a	IMP		Mouse	MGI:MGI:5285168|PMID:19755709
Biological Process	GO:0006801	superoxide metabolic process	SH3PXD2A	IDA		Human	PMID:19755710
Biological Process	GO:0006801	superoxide metabolic process	SH3PXD2A	IMP		Human	PMID:20609497

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern