Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SH3RF1
  • Mouse genes Sh3rf1
  • Rat genes Sh3rf1
  • Zfish genes sh3rf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sh3rf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005078	MAP-kinase scaffold activity	Sh3rf1	IPI	UniProtKB:Q9WVI9	Mouse	MGI:MGI:5546548|PMID:23963642
Molecular Function	GO:0005515	protein binding	SH3RF1	IPI	UniProtKB:P63000	Human	PMID:20696164
Molecular Function	GO:0005515	protein binding	SH3RF1	IPI	UniProtKB:P63000	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	SH3RF1	IPI	UniProtKB:O43255	Human	PMID:21586138
Molecular Function	GO:0005515	protein binding	SH3RF1	IPI	UniProtKB:O43255	Human	PMID:25438054
Molecular Function	GO:0005515	protein binding	Sh3rf1	IPI	UniProtKB:Q9Z2F7	Mouse	MGI:MGI:3828389|PMID:17095503
Molecular Function	GO:0005515	protein binding	Sh3rf1	IPI	UniProtKB:Q8IUQ4	Mouse	MGI:MGI:3696630|PMID:16230351
Molecular Function	GO:0005515	protein binding	Sh3rf1	IPI	UniProtKB:Q9WVI9	Mouse	MGI:MGI:5546548|PMID:23963642
Molecular Function	GO:0005515	protein binding	Sh3rf1	IPI	UniProtKB:P63001	Mouse	MGI:MGI:6158752|PMID:22959435
Molecular Function	GO:0005515	protein binding	Sh3rf1	IPI	UniProtKB:Q920M9	Rat	PMID:16230351|RGD:8554714
Molecular Function	GO:0005515	protein binding	Sh3rf1	IPI	UniProtKB:Q498M5	Rat	PMID:22128169|RGD:13673844
Molecular Function	GO:0061630	ubiquitin protein ligase activity	SH3RF1	IMP		Human	PMID:20696164
Cellular Component	GO:0005829	cytosol	SH3RF1	IDA		Human	PMID:21586138
Cellular Component	GO:0030027	lamellipodium	Sh3rf1	IDA		Mouse	MGI:MGI:6158752|PMID:22959435
Biological Process	GO:0043066	negative regulation of apoptotic process	SH3RF1	IMP		Human	PMID:21586138
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	SH3RF1	IMP		Human	PMID:21586138
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	SH3RF1	IMP		Human	PMID:21586138
Biological Process	GO:0001764	neuron migration	Sh3rf1	IMP		Mouse	MGI:MGI:6158752|PMID:22959435
Biological Process	GO:0046330	positive regulation of JNK cascade	Sh3rf1	IMP		Mouse	MGI:MGI:6158776|PMID:27084103
Biological Process	GO:0046330	positive regulation of JNK cascade	Sh3rf1	IMP		Mouse	MGI:MGI:5546548|PMID:23963642
Biological Process	GO:0051865	protein autoubiquitination	SH3RF1	IMP		Human	PMID:20696164
Biological Process	GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	Sh3rf1	IMP		Mouse	MGI:MGI:6158776|PMID:27084103
Biological Process	GO:2000564	regulation of CD8-positive, alpha-beta T cell proliferation	Sh3rf1	IMP		Mouse	MGI:MGI:5546548|PMID:23963642

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern