Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SH3RF2
  • Mouse genes Sh3rf2
  • Rat genes Sh3rf2
  • Zfish genes sh3rf2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sh3rf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019902	phosphatase binding	SH3RF2	IDA		Human	PMID:19389623
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:P62136	Human	PMID:19389623
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:P62139	Human	PMID:19945436
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:P62136	Human	PMID:22321011
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:O96013|UniProtKB:P19438	Human	PMID:24130170
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:Q8N9N5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:Q08379	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:Q5JR59-3	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:Q9Y2J4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:A5D8V6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:O43281-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:O95429	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:Q68D86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:Q9HC98-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:Q9ULX6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SH3RF2	IPI	UniProtKB:Q9Y2J4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Sh3rf2	IPI	UniProtKB:D3ZG83|UniProtKB:E9PSK7|UniProtKB:G3V9M2|UniProtKB:O70534|UniProtKB:Q6RUV5|UniProtKB:Q71F54|UniProtKB:Q9R237	Rat	PMID:22128169|RGD:13673844
Molecular Function	GO:0008157	protein phosphatase 1 binding	SH3RF2	IDA		Human	PMID:19945436
Molecular Function	GO:0061630	ubiquitin protein ligase activity	SH3RF2	IMP		Human	PMID:24130170
Cellular Component	GO:0005654	nucleoplasm	SH3RF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SH3RF2	IDA		Human	PMID:24130170
Biological Process	GO:0043066	negative regulation of apoptotic process	SH3RF2	IMP		Human	PMID:24130170
Biological Process	GO:0043066	negative regulation of apoptotic process	Sh3rf2	IMP		Rat	PMID:22128169|RGD:13673844
Biological Process	GO:0046329	negative regulation of JNK cascade	Sh3rf2	IMP		Rat	PMID:22128169|RGD:13673844
Biological Process	GO:0031397	negative regulation of protein ubiquitination	SH3RF2	IMP		Human	PMID:24130170
Biological Process	GO:0030335	positive regulation of cell migration	SH3RF2	IMP		Human	PMID:24130170
Biological Process	GO:0046330	positive regulation of JNK cascade	SH3RF2	IMP		Human	PMID:24130170
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	SH3RF2	IMP		Human	PMID:22128169
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Sh3rf2	IMP		Rat	PMID:22128169|RGD:13673844
Biological Process	GO:0051865	protein autoubiquitination	SH3RF2	IMP		Human	PMID:24130170

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern