Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SHB
  • Mouse genes Shb
  • Rat genes Shb
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Shb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001784	phosphotyrosine residue binding	SHB	IPI	UniProtKB:Q6GX35	Human	PMID:20624904
Molecular Function	GO:0005515	protein binding	SHB	IPI	UniProtKB:P00519	Human	PMID:17112510
Molecular Function	GO:0005515	protein binding	SHB	IPI	UniProtKB:P08581	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	SHB	IPI	UniProtKB:P10721	Human	PMID:24728074
Molecular Function	GO:0030159	signaling receptor complex adaptor activity	Shb	IDA		Mouse	PMID:8302579
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	SHB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	SHB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SHB	IDA		Human	GO_REF:0000052
Biological Process	GO:0042100	B cell proliferation	Shb	IDA		Mouse	PMID:11786382
Biological Process	GO:0001568	blood vessel development	Shb	IMP	MGI:MGI:3721903	Mouse	PMID:19223532
Biological Process	GO:0048514	blood vessel morphogenesis	Shb	IGI	MGI:MGI:97528	Mouse	PMID:15919073
Biological Process	GO:0048514	blood vessel morphogenesis	Shb	IMP		Mouse	PMID:15919073
Biological Process	GO:0048514	blood vessel morphogenesis	Shb	IGI	MGI:MGI:103178	Mouse	PMID:15919073
Biological Process	GO:0071425	hematopoietic stem cell proliferation	Shb	IMP	MGI:MGI:3721903	Mouse	PMID:23528453
Biological Process	GO:0030097	hemopoiesis	Shb	IMP	MGI:MGI:3721903	Mouse	PMID:16971391
Biological Process	GO:1900194	negative regulation of oocyte maturation	Shb	IMP	MGI:MGI:3721903	Mouse	PMID:20585392
Biological Process	GO:0006469	negative regulation of protein kinase activity	Shb	IMP	MGI:MGI:3721903	Mouse	PMID:23528453
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	Shb	IMP	MGI:MGI:3721903	Mouse	PMID:23528453
Biological Process	GO:0045624	positive regulation of T-helper cell differentiation	Shb	IMP	MGI:MGI:3721903	Mouse	PMID:24645804
Biological Process	GO:0050852	T cell receptor signaling pathway	Shb	IMP	MGI:MGI:3721903	Mouse	PMID:24645804

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern