Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SHOC2
  • Mouse genes Shoc2
  • Rat genes Shoc2
  • Zfish genes shoc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Shoc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SHOC2	IPI	UniProtKB:O14807|UniProtKB:P04049	Human	PMID:25137548
Molecular Function	GO:0008157	protein phosphatase 1 binding	SHOC2	IDA		Human	PMID:25137548
Molecular Function	GO:0019903	protein phosphatase binding	SHOC2	IDA		Human	PMID:16630891
Cellular Component	GO:0005737	cytoplasm	SHOC2	IDA		Human	PMID:19684605
Cellular Component	GO:0005737	cytoplasm	SHOC2	IDA		Human	PMID:25137548
Cellular Component	GO:0005829	cytosol	SHOC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SHOC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SHOC2	IDA		Human	PMID:19684605
Cellular Component	GO:0000164	protein phosphatase type 1 complex	SHOC2	IDA		Human	PMID:16630891
Cellular Component	GO:0000164	protein phosphatase type 1 complex	SHOC2	IDA		Human	PMID:25137548
Biological Process	GO:0071378	cellular response to growth hormone stimulus	Shoc2	IEP		Rat	PMID:15300589|RGD:155804276
Biological Process	GO:2000178	negative regulation of neural precursor cell proliferation	Shoc2	IMP		Rat	PMID:21732489|RGD:155804271
Biological Process	GO:0045665	negative regulation of neuron differentiation	Shoc2	IMP		Rat	PMID:21732489|RGD:155804271
Biological Process	GO:0038180	nerve growth factor signaling pathway	Shoc2	IMP		Rat	PMID:25514808|RGD:155804270
Biological Process	GO:0045666	positive regulation of neuron differentiation	Shoc2	IMP		Rat	PMID:25514808|RGD:155804270
Biological Process	GO:0010976	positive regulation of neuron projection development	Shoc2	IMP		Rat	PMID:25514808|RGD:155804270
Biological Process	GO:0046579	positive regulation of Ras protein signal transduction	SHOC2	IMP		Human	PMID:16630891
Biological Process	GO:0046579	positive regulation of Ras protein signal transduction	SHOC2	IMP		Human	PMID:19684605

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern