Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SIGMAR1
  • Mouse genes Sigmar1
  • Rat genes Sigmar1
  • Zfish genes sigmar1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sigmar1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004985	G protein-coupled opioid receptor activity	Sigmar1	IDA		Rat	PMID:12438547|RGD:633427
Molecular Function	GO:0005515	protein binding	SIGMAR1	IPI	UniProtKB:Q92847-1	Human	PMID:29876881
Molecular Function	GO:0005515	protein binding	Sigmar1	IPI	UniProtKB:P63141	Mouse	MGI:MGI:5493175|PMID:23332758
Molecular Function	GO:0005515	protein binding	Sigmar1	IPI	UniProtKB:Q96DY5	Mouse	MGI:MGI:6154438|PMID:26792191
Molecular Function	GO:0005515	protein binding	Sigmar1	IPI	UniProtKB:G3I8R9	Mouse	MGI:MGI:5315697|PMID:17981125
Molecular Function	GO:0005515	protein binding	Sigmar1	IPI	UniProtKB:P06761	Rat	PMID:17981125|RGD:8554014
Molecular Function	GO:0005515	protein binding	Sigmar1	IPI	UniProtKB:P63141	Rat	PMID:23332758|RGD:8554497
Molecular Function	GO:0038023	signaling receptor activity	Sigmar1	IDA		Mouse	PMID:14622179
Cellular Component	GO:0005783	endoplasmic reticulum	SIGMAR1	IDA		Human	PMID:10406945
Cellular Component	GO:0016020	membrane	SIGMAR1	IDA		Human	PMID:27042935
Cellular Component	GO:0016020	membrane	SIGMAR1	IDA		Human	PMID:8954936
Cellular Component	GO:0005635	nuclear envelope	SIGMAR1	IDA		Human	PMID:10406945
Cellular Component	GO:0005635	nuclear envelope	SIGMAR1	IDA		Human	PMID:9341151
Cellular Component	GO:0014069	postsynaptic density	SIGMAR1	IDA		Human	PMID:23314020
Cellular Component	GO:0014069	postsynaptic density	Sigmar1	IDA		Mouse	MGI:MGI:4452289|PMID:20167253
Biological Process	GO:0036474	cell death in response to hydrogen peroxide	Sigmar1	IMP		Mouse	MGI:MGI:6154438|PMID:26792191
Biological Process	GO:0007399	nervous system development	Sigmar1	IDA		Rat	PMID:12438547|RGD:633427
Biological Process	GO:0070207	protein homotrimerization	SIGMAR1	IPI	UniProtKB:Q99720	Human	PMID:27042935
Biological Process	GO:0043523	regulation of neuron apoptotic process	SIGMAR1	IMP		Human	PMID:21842496
Biological Process	GO:0009611	response to wounding	sigmar1	IMP	ZFIN:ZDB-MRPHLNO-150610-1	Zfish	PMID:25666889

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern