Source |
Alliance of Genome Resources |
Category | ID | Classification term | Gene | Evidence | Inferred from | Organism | Reference |
---|---|---|---|---|---|---|---|
Molecular Function | GO:0003682 | chromatin binding | SIRT6 | IDA | Human | PMID:27043296 | |
Molecular Function | GO:0003682 | chromatin binding | SIRT6 | IDA | Human | PMID:27912097 | |
Molecular Function | GO:0003682 | chromatin binding | Sirt6 | IDA | Mouse | PMID:24105743 | |
Molecular Function | GO:0031490 | chromatin DNA binding | SIRT6 | IDA | Human | PMID:33067423 | |
Molecular Function | GO:0003684 | damaged DNA binding | SIRT6 | IDA | Human | PMID:31995034 | |
Molecular Function | GO:0003684 | damaged DNA binding | SIRT6 | IDA | Human | PMID:32538779 | |
Molecular Function | GO:0140612 | DNA damage sensor activity | SIRT6 | IDA | Human | PMID:31995034 | |
Molecular Function | GO:0140612 | DNA damage sensor activity | SIRT6 | IDA | Human | PMID:32538779 | |
Molecular Function | GO:0008047 | enzyme activator activity | SIRT6 | IDA | Human | PMID:23892288 | |
Molecular Function | GO:0008047 | enzyme activator activity | SIRT6 | IDA | Human | PMID:27043296 | |
Molecular Function | GO:0008047 | enzyme activator activity | SIRT6 | IDA | Human | PMID:31995034 | |
Molecular Function | GO:0008047 | enzyme activator activity | SIRT6 | IDA | Human | PMID:32538779 | |
Molecular Function | GO:0008047 | enzyme activator activity | SIRT6 | IDA | Human | PMID:33067423 | |
Molecular Function | GO:0035033 | histone deacetylase regulator activity | SIRT6 | IDA | Human | PMID:23892288 | |
Molecular Function | GO:0035033 | histone deacetylase regulator activity | SIRT6 | IDA | Human | PMID:27043296 | |
Molecular Function | GO:0035033 | histone deacetylase regulator activity | SIRT6 | IDA | Human | PMID:31995034 | |
Molecular Function | GO:0035033 | histone deacetylase regulator activity | SIRT6 | IDA | Human | PMID:32538779 | |
Molecular Function | GO:0035033 | histone deacetylase regulator activity | SIRT6 | IDA | Human | PMID:33067423 | |
Molecular Function | GO:0106222 | lncRNA binding | SIRT6 | IDA | Human | PMID:27912097 | |
Molecular Function | GO:0140677 | molecular function activator activity | SIRT6 | IDA | Human | PMID:21680843 | |
Molecular Function | GO:0140677 | molecular function activator activity | SIRT6 | IDA | Human | PMID:23552949 | |
Molecular Function | GO:0140677 | molecular function activator activity | SIRT6 | IDA | Human | PMID:27568560 | |
Molecular Function | GO:0140677 | molecular function activator activity | SIRT6 | IDA | Human | PMID:30374165 | |
Molecular Function | GO:0140677 | molecular function activator activity | SIRT6 | IDA | Human | PMID:31995034 | |
Molecular Function | GO:0140677 | molecular function activator activity | SIRT6 | IDA | Human | PMID:32538779 | |
Molecular Function | GO:0140677 | molecular function activator activity | Sirt6 | IDA | Mouse | PMID:31399344 | |
Molecular Function | GO:1990404 | NAD+-protein ADP-ribosyltransferase activity | SIRT6 | IDA | Human | PMID:21680843 | |
Molecular Function | GO:1990404 | NAD+-protein ADP-ribosyltransferase activity | SIRT6 | IDA | Human | PMID:22753495 | |
Molecular Function | GO:1990404 | NAD+-protein ADP-ribosyltransferase activity | SIRT6 | IDA | Human | PMID:27322069 | |
Molecular Function | GO:1990404 | NAD+-protein ADP-ribosyltransferase activity | SIRT6 | IDA | Human | PMID:27568560 | |
Molecular Function | GO:1990404 | NAD+-protein ADP-ribosyltransferase activity | Sirt6 | IDA | Mouse | MGI:MGI:6455956|PMID:31216030 | |
Molecular Function | GO:1990404 | NAD+-protein ADP-ribosyltransferase activity | Sirt6 | IDA | Mouse | MGI:MGI:6214653|PMID:25247314 | |
Molecular Function | GO:0106274 | NAD+-protein-arginine ADP-ribosyltransferase activity | Sirt6 | IDA | Mouse | MGI:MGI:3584210|PMID:15795229 | |
Molecular Function | GO:0106274 | NAD+-protein-arginine ADP-ribosyltransferase activity | Sirt6 | IDA | Mouse | MGI:MGI:6694658|PMID:32584788 | |
Molecular Function | GO:0017136 | NAD-dependent histone deacetylase activity | SIRT6 | IDA | Human | PMID:24043303 | |
Molecular Function | GO:0017136 | NAD-dependent histone deacetylase activity | SIRT6 | IDA | Human | PMID:27912097 | |
Molecular Function | GO:0097372 | NAD-dependent histone H3K18 deacetylase activity | SIRT6 | IDA | Human | PMID:27043296 | |
Molecular Function | GO:0097372 | NAD-dependent histone H3K18 deacetylase activity | Sirt6 | IDA | Mouse | MGI:MGI:7258357|PMID:31002797 | |
Molecular Function | GO:0140765 | NAD-dependent histone H3K56 deacetylase activity | SIRT6 | IDA | Human | PMID:23911928 | |
Molecular Function | GO:0140765 | NAD-dependent histone H3K56 deacetylase activity | SIRT6 | IDA | Human | PMID:26456828 | |
Molecular Function | GO:0140765 | NAD-dependent histone H3K56 deacetylase activity | SIRT6 | IDA | Human | PMID:26898756 | |
Molecular Function | GO:0140765 | NAD-dependent histone H3K56 deacetylase activity | SIRT6 | IDA | Human | PMID:27912097 | |
Molecular Function | GO:0140765 | NAD-dependent histone H3K56 deacetylase activity | SIRT6 | IDA | Human | PMID:30374165 | |
Molecular Function | GO:0140765 | NAD-dependent histone H3K56 deacetylase activity | Sirt6 | IDA | Mouse | MGI:MGI:7258357|PMID:31002797 | |
Molecular Function | GO:0140765 | NAD-dependent histone H3K56 deacetylase activity | Sirt6 | IDA | Mouse | MGI:MGI:4867348|PMID:21098266 | |
Molecular Function | GO:0140765 | NAD-dependent histone H3K56 deacetylase activity | Sirt6 | IDA | Mouse | MGI:MGI:6103696|PMID:28355567 | |
Molecular Function | GO:0140765 | NAD-dependent histone H3K56 deacetylase activity | Sirt6 | IDA | Mouse | MGI:MGI:6757299|PMID:25915124 | |
Molecular Function | GO:0140765 | NAD-dependent histone H3K56 deacetylase activity | Sirt6 | IDA | Mouse | PMID:31399344 | |
Molecular Function | GO:0046969 | NAD-dependent histone H3K9 deacetylase activity | SIRT6 | IDA | Human | PMID:18337721 | |
Molecular Function | GO:0046969 | NAD-dependent histone H3K9 deacetylase activity | SIRT6 | IDA | Human | PMID:23892288 | |
Molecular Function | GO:0046969 | NAD-dependent histone H3K9 deacetylase activity | SIRT6 | IDA | Human | PMID:26456828 | |
Molecular Function | GO:0046969 | NAD-dependent histone H3K9 deacetylase activity | SIRT6 | IMP | Human | PMID:29555651 | |
Molecular Function | GO:0046969 | NAD-dependent histone H3K9 deacetylase activity | SIRT6 | IDA | Human | PMID:30374165 | |
Molecular Function | GO:0046969 | NAD-dependent histone H3K9 deacetylase activity | SIRT6 | IDA | Human | PMID:33067423 | |
Molecular Function | GO:0046969 | NAD-dependent histone H3K9 deacetylase activity | Sirt6 | IMP | Mouse | MGI:MGI:6103696|PMID:28355567 | |
Molecular Function | GO:0046969 | NAD-dependent histone H3K9 deacetylase activity | Sirt6 | IMP | Mouse | MGI:MGI:6357632|PMID:31399344 | |
Molecular Function | GO:0046969 | NAD-dependent histone H3K9 deacetylase activity | Sirt6 | IMP | Mouse | MGI:MGI:4867348|PMID:21098266 | |
Molecular Function | GO:0046969 | NAD-dependent histone H3K9 deacetylase activity | Sirt6 | IMP | Mouse | MGI:MGI:6757299|PMID:25915124 | |
Molecular Function | GO:0046969 | NAD-dependent histone H3K9 deacetylase activity | Sirt6 | IDA | Mouse | MGI:MGI:7258357|PMID:31002797 | |
Molecular Function | GO:0046969 | NAD-dependent histone H3K9 deacetylase activity | Sirt6 | IMP | Mouse | MGI:MGI:4881401|PMID:20141841 | |
Molecular Function | GO:0046969 | NAD-dependent histone H3K9 deacetylase activity | Sirt6 | IMP | Mouse | MGI:MGI:6284084|PMID:29555651 | |
Molecular Function | GO:0046969 | NAD-dependent histone H3K9 deacetylase activity | Sirt6 | IDA | Mouse | PMID:31399344 | |
Molecular Function | GO:0034979 | NAD-dependent protein deacetylase activity | SIRT6 | IDA | Human | PMID:19109893 | |
Molecular Function | GO:0034979 | NAD-dependent protein deacetylase activity | SIRT6 | IDA | Human | PMID:23142079 | |
Molecular Function | GO:0034979 | NAD-dependent protein deacetylase activity | SIRT6 | IDA | Human | PMID:24052263 | |
Molecular Function | GO:0034979 | NAD-dependent protein deacetylase activity | SIRT6 | IDA | Human | PMID:25009184 | |
Molecular Function | GO:0034979 | NAD-dependent protein deacetylase activity | SIRT6 | IDA | Human | PMID:26787900 | |
Molecular Function | GO:0034979 | NAD-dependent protein deacetylase activity | SIRT6 | IDA | Human | PMID:27322069 | |
Molecular Function | GO:0034979 | NAD-dependent protein deacetylase activity | SIRT6 | IDA | Human | PMID:29474172 | |
Molecular Function | GO:0034979 | NAD-dependent protein deacetylase activity | Sirt6 | IDA | Mouse | MGI:MGI:6443593|PMID:30782483 | |
Molecular Function | GO:0034979 | NAD-dependent protein deacetylase activity | Sirt6 | IDA | Mouse | MGI:MGI:6357356|PMID:31442424 | |
Molecular Function | GO:0034979 | NAD-dependent protein deacetylase activity | Sirt6 | IDA | Mouse | MGI:MGI:6429981|PMID:31851938 | |
Molecular Function | GO:0034979 | NAD-dependent protein deacetylase activity | Sirt6 | IDA | Mouse | MGI:MGI:6101624|PMID:27457971 | |
Molecular Function | GO:0140773 | NAD-dependent protein demyristoylase activity | SIRT6 | IDA | Human | PMID:23552949 | |
Molecular Function | GO:0140773 | NAD-dependent protein demyristoylase activity | SIRT6 | IDA | Human | PMID:24052263 | |
Molecular Function | GO:0140773 | NAD-dependent protein demyristoylase activity | SIRT6 | IDA | Human | PMID:26456828 | |
Molecular Function | GO:0140773 | NAD-dependent protein demyristoylase activity | SIRT6 | IDA | Human | PMID:27322069 | |
Molecular Function | GO:0140773 | NAD-dependent protein demyristoylase activity | SIRT6 | IDA | Human | PMID:30374165 | |
Molecular Function | GO:0140773 | NAD-dependent protein demyristoylase activity | SIRT6 | IDA | Human | PMID:31995034 | |
Molecular Function | GO:0140774 | NAD-dependent protein depalmitoylase activity | SIRT6 | IDA | Human | PMID:23552949 | |
Molecular Function | GO:0140774 | NAD-dependent protein depalmitoylase activity | SIRT6 | IDA | Human | PMID:24052263 | |
Molecular Function | GO:0140774 | NAD-dependent protein depalmitoylase activity | SIRT6 | IDA | Human | PMID:27322069 | |
Molecular Function | GO:0140774 | NAD-dependent protein depalmitoylase activity | SIRT6 | IDA | Human | PMID:28406396 | |
Molecular Function | GO:0140774 | NAD-dependent protein depalmitoylase activity | SIRT6 | IMP | Human | PMID:29555651 | |
Molecular Function | GO:0031491 | nucleosome binding | SIRT6 | IDA | Human | PMID:23892288 | |
Molecular Function | GO:0031491 | nucleosome binding | SIRT6 | IDA | Human | PMID:33067423 | |
Molecular Function | GO:0005515 | protein binding | SIRT6 | IPI | UniProtKB:Q04206 | Human | PMID:19135889 |
Molecular Function | GO:0005515 | protein binding | SIRT6 | IPI | UniProtKB:P01106 | Human | PMID:23217706 |
Molecular Function | GO:0005515 | protein binding | SIRT6 | IPI | UniProtKB:O60264 | Human | PMID:23911928 |
Molecular Function | GO:0005515 | protein binding | Sirt6 | IPI | RGD:727889 | Rat | PMID:22335191|RGD:9586060 |
Molecular Function | GO:0042803 | protein homodimerization activity | SIRT6 | IDA | Human | PMID:31995034 | |
Molecular Function | GO:0042803 | protein homodimerization activity | SIRT6 | IDA | Human | PMID:32538779 | |
Molecular Function | GO:0033558 | protein lysine deacetylase activity | Sirt6 | IDA | Rat | PMID:22335191|RGD:9586060 | |
Molecular Function | GO:1904841 | TORC2 complex binding | Sirt6 | IDA | Mouse | MGI:MGI:6357356|PMID:31442424 | |
Molecular Function | GO:0003714 | transcription corepressor activity | Sirt6 | IGI | UniProtKB:P01108 | Mouse | MGI:MGI:5619441|PMID:23217706 |
Molecular Function | GO:0140416 | transcription regulator inhibitor activity | SIRT6 | IDA | Human | PMID:29474172 | |
Cellular Component | GO:0000785 | chromatin | SIRT6 | IDA | Human | PMID:23892288 | |
Cellular Component | GO:0000785 | chromatin | SIRT6 | IDA | Human | PMID:27043296 | |
Cellular Component | GO:0000785 | chromatin | SIRT6 | IDA | Human | PMID:27912097 | |
Cellular Component | GO:0000785 | chromatin | SIRT6 | IDA | Human | PMID:30374165 | |
Cellular Component | GO:0000785 | chromatin | SIRT6 | IDA | Human | PMID:33067423 | |
Cellular Component | GO:0000785 | chromatin | SIRT6 | IDA | Human | PMID:26456828 | |
Cellular Component | GO:0000785 | chromatin | Sirt6 | IDA | Mouse | PMID:31399344 | |
Cellular Component | GO:0099115 | chromosome, subtelomeric region | SIRT6 | IDA | Human | PMID:18337721 | |
Cellular Component | GO:0005737 | cytoplasm | Sirt6 | IDA | Rat | PMID:21502801|RGD:9586061 | |
Cellular Component | GO:0005783 | endoplasmic reticulum | SIRT6 | IDA | Human | PMID:23552949 | |
Cellular Component | GO:0043231 | intracellular membrane-bounded organelle | SIRT6 | IDA | Human | GO_REF:0000052 | |
Cellular Component | GO:0005654 | nucleoplasm | SIRT6 | IDA | Human | GO_REF:0000052 | |
Cellular Component | GO:0005654 | nucleoplasm | SIRT6 | IDA | Human | PMID:16079181 | |
Cellular Component | GO:0005634 | nucleus | SIRT6 | IDA | Human | PMID:26898756 | |
Cellular Component | GO:0005634 | nucleus | SIRT6 | IDA | Human | PMID:29555651 | |
Cellular Component | GO:0005634 | nucleus | SIRT6 | IDA | Human | PMID:25819580 | |
Cellular Component | GO:0005634 | nucleus | SIRT6 | IDA | Human | PMID:26456828 | |
Cellular Component | GO:0005634 | nucleus | Sirt6 | IDA | Mouse | MGI:MGI:5619429|PMID:24063863 | |
Cellular Component | GO:0005634 | nucleus | Sirt6 | IDA | Mouse | MGI:MGI:3584210|PMID:15795229 | |
Cellular Component | GO:0005634 | nucleus | Sirt6 | IDA | Rat | PMID:21502801|RGD:9586061 | |
Cellular Component | GO:0005721 | pericentric heterochromatin | SIRT6 | IDA | Human | PMID:27043296 | |
Cellular Component | GO:0090734 | site of DNA damage | SIRT6 | IDA | Human | PMID:19109893 | |
Cellular Component | GO:0035861 | site of double-strand break | SIRT6 | IDA | Human | PMID:21680843 | |
Cellular Component | GO:0035861 | site of double-strand break | SIRT6 | IDA | Human | PMID:23911928 | |
Cellular Component | GO:0035861 | site of double-strand break | SIRT6 | IDA | Human | PMID:27568560 | |
Cellular Component | GO:0035861 | site of double-strand break | SIRT6 | IDA | Human | PMID:31995034 | |
Cellular Component | GO:0035861 | site of double-strand break | SIRT6 | IDA | Human | PMID:32538779 | |
Biological Process | GO:0006284 | base-excision repair | Sirt6 | IMP | Mouse | MGI:MGI:3663736|PMID:16439206 | |
Biological Process | GO:0055007 | cardiac muscle cell differentiation | Sirt6 | IMP | Mouse | MGI:MGI:6284084|PMID:29555651 | |
Biological Process | GO:1904385 | cellular response to angiotensin | Sirt6 | IEP | Rat | PMID:30894089|RGD:155260334 | |
Biological Process | GO:1990859 | cellular response to endothelin | Sirt6 | IEP | Rat | PMID:30894089|RGD:155260334 | |
Biological Process | GO:0070301 | cellular response to hydrogen peroxide | Sirt6 | IEP | Rat | PMID:30894089|RGD:155260334 | |
Biological Process | GO:0032922 | circadian regulation of gene expression | Sirt6 | IMP | Mouse | MGI:MGI:5603468|PMID:25083875 | |
Biological Process | GO:0008340 | determination of adult lifespan | SIRT6 | IMP | Human | PMID:25541994 | |
Biological Process | GO:0008340 | determination of adult lifespan | Sirt6 | IMP | Mouse | MGI:MGI:7258357|PMID:31002797 | |
Biological Process | GO:0006281 | DNA repair | Sirt6 | IDA | Mouse | MGI:MGI:6694658|PMID:32584788 | |
Biological Process | GO:0006302 | double-strand break repair | SIRT6 | IDA | Human | PMID:21680843 | |
Biological Process | GO:0006302 | double-strand break repair | SIRT6 | IDA | Human | PMID:27568560 | |
Biological Process | GO:0042593 | glucose homeostasis | Sirt6 | IMP | Mouse | MGI:MGI:3663736|PMID:16439206 | |
Biological Process | GO:0016575 | histone deacetylation | SIRT6 | IDA | Human | PMID:23892288 | |
Biological Process | GO:0042181 | ketone biosynthetic process | Sirt6 | IMP | Mouse | MGI:MGI:6294537|PMID:30530497 | |
Biological Process | GO:0008285 | negative regulation of cell population proliferation | Sirt6 | IMP | Mouse | MGI:MGI:5619441|PMID:23217706 | |
Biological Process | GO:2000773 | negative regulation of cellular senescence | SIRT6 | IDA | Human | PMID:22753495 | |
Biological Process | GO:2000773 | negative regulation of cellular senescence | SIRT6 | IDA | Human | PMID:27043296 | |
Biological Process | GO:2000773 | negative regulation of cellular senescence | SIRT6 | IMP | Human | PMID:29474172 | |
Biological Process | GO:0045892 | negative regulation of DNA-templated transcription | Sirt6 | IMP | Mouse | MGI:MGI:4881401|PMID:20141841 | |
Biological Process | GO:0045814 | negative regulation of gene expression, epigenetic | SIRT6 | IMP | Human | PMID:21847107 | |
Biological Process | GO:0045721 | negative regulation of gluconeogenesis | SIRT6 | IDA | Human | PMID:23142079 | |
Biological Process | GO:0045721 | negative regulation of gluconeogenesis | SIRT6 | IDA | Human | PMID:25009184 | |
Biological Process | GO:0046325 | negative regulation of glucose import | Sirt6 | IMP | Mouse | MGI:MGI:4881401|PMID:20141841 | |
Biological Process | GO:0045820 | negative regulation of glycolytic process | SIRT6 | IDA | Human | PMID:26456828 | |
Biological Process | GO:0045820 | negative regulation of glycolytic process | Sirt6 | IMP | Mouse | MGI:MGI:5619441|PMID:23217706 | |
Biological Process | GO:0045820 | negative regulation of glycolytic process | Sirt6 | IMP | Mouse | MGI:MGI:4881401|PMID:20141841 | |
Biological Process | GO:0042308 | negative regulation of protein import into nucleus | Sirt6 | IMP | Mouse | MGI:MGI:6103696|PMID:28355567 | |
Biological Process | GO:0120186 | negative regulation of protein localization to chromatin | SIRT6 | IDA | Human | PMID:27912097 | |
Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II | SIRT6 | IDA | Human | PMID:24043303 | |
Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II | Sirt6 | IMP | Mouse | MGI:MGI:6357632|PMID:31399344 | |
Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II | Sirt6 | IMP | Mouse | MGI:MGI:6103696|PMID:28355567 | |
Biological Process | GO:0034244 | negative regulation of transcription elongation by RNA polymerase II | Sirt6 | IDA | Mouse | MGI:MGI:6214653|PMID:25247314 | |
Biological Process | GO:0034244 | negative regulation of transcription elongation by RNA polymerase II | Sirt6 | IDA | Mouse | PMID:31399344 | |
Biological Process | GO:0010529 | negative regulation of transposition | Sirt6 | IMP | Mouse | MGI:MGI:6303534|PMID:30853213 | |
Biological Process | GO:0010529 | negative regulation of transposition | Sirt6 | IDA | Mouse | MGI:MGI:6214653|PMID:25247314 | |
Biological Process | GO:0031508 | pericentric heterochromatin formation | SIRT6 | IDA | Human | PMID:27043296 | |
Biological Process | GO:1905555 | positive regulation of blood vessel branching | SIRT6 | IMP | Human | PMID:23201774 | |
Biological Process | GO:1902732 | positive regulation of chondrocyte proliferation | SIRT6 | IMP | Human | PMID:25819580 | |
Biological Process | GO:0120162 | positive regulation of cold-induced thermogenesis | Sirt6 | IMP | Mouse | MGI:MGI:6101021|PMID:28723567 | |
Biological Process | GO:2000781 | positive regulation of double-strand break repair | SIRT6 | IDA | Human | PMID:23911928 | |
Biological Process | GO:2000781 | positive regulation of double-strand break repair | SIRT6 | IDA | Human | PMID:31995034 | |
Biological Process | GO:2000781 | positive regulation of double-strand break repair | SIRT6 | IDA | Human | PMID:32538779 | |
Biological Process | GO:2000781 | positive regulation of double-strand break repair | Sirt6 | IDA | Mouse | MGI:MGI:7258357|PMID:31002797 | |
Biological Process | GO:0045600 | positive regulation of fat cell differentiation | Sirt6 | IMP | Mouse | MGI:MGI:6103696|PMID:28355567 | |
Biological Process | GO:0048146 | positive regulation of fibroblast proliferation | Sirt6 | IMP | Mouse | MGI:MGI:3663736|PMID:16439206 | |
Biological Process | GO:1901727 | positive regulation of histone deacetylase activity | SIRT6 | IDA | Human | PMID:23892288 | |
Biological Process | GO:1901727 | positive regulation of histone deacetylase activity | SIRT6 | IDA | Human | PMID:33067423 | |
Biological Process | GO:0032024 | positive regulation of insulin secretion | Sirt6 | IDA | Mouse | MGI:MGI:6101624|PMID:27457971 | |
Biological Process | GO:0046827 | positive regulation of protein export from nucleus | SIRT6 | IDA | Human | PMID:25009184 | |
Biological Process | GO:0046827 | positive regulation of protein export from nucleus | SIRT6 | IDA | Human | PMID:26787900 | |
Biological Process | GO:0046827 | positive regulation of protein export from nucleus | Sirt6 | IDA | Mouse | MGI:MGI:6101624|PMID:27457971 | |
Biological Process | GO:0120187 | positive regulation of protein localization to chromatin | Sirt6 | IMP | Mouse | MGI:MGI:6357632|PMID:31399344 | |
Biological Process | GO:0120187 | positive regulation of protein localization to chromatin | Sirt6 | IDA | Mouse | PMID:31399344 | |
Biological Process | GO:2000738 | positive regulation of stem cell differentiation | SIRT6 | IDA | Human | PMID:27912097 | |
Biological Process | GO:2000738 | positive regulation of stem cell differentiation | Sirt6 | IMP | Mouse | MGI:MGI:6757299|PMID:25915124 | |
Biological Process | GO:2000738 | positive regulation of stem cell differentiation | Sirt6 | IMP | Mouse | MGI:MGI:6284084|PMID:29555651 | |
Biological Process | GO:1902459 | positive regulation of stem cell population maintenance | SIRT6 | IDA | Human | PMID:27912097 | |
Biological Process | GO:2000648 | positive regulation of stem cell proliferation | Sirt6 | IMP | Mouse | MGI:MGI:3663736|PMID:16439206 | |
Biological Process | GO:0032206 | positive regulation of telomere maintenance | SIRT6 | IMP | Human | PMID:23201774 | |
Biological Process | GO:0032206 | positive regulation of telomere maintenance | SIRT6 | IMP | Human | PMID:25819580 | |
Biological Process | GO:1901485 | positive regulation of transcription factor catabolic process | SIRT6 | IMP | Human | PMID:27457971 | |
Biological Process | GO:1905564 | positive regulation of vascular endothelial cell proliferation | SIRT6 | IMP | Human | PMID:23201774 | |
Biological Process | GO:0003247 | post-embryonic cardiac muscle cell growth involved in heart morphogenesis | Sirt6 | IMP | Rat | PMID:22335191|RGD:9586060 | |
Biological Process | GO:0006476 | protein deacetylation | SIRT6 | IMP | Human | PMID:27457971 | |
Biological Process | GO:0006476 | protein deacetylation | Sirt6 | IMP | Mouse | MGI:MGI:6101624|PMID:27457971 | |
Biological Process | GO:0051697 | protein delipidation | SIRT6 | IDA | Human | PMID:23552949 | |
Biological Process | GO:0031648 | protein destabilization | SIRT6 | IDA | Human | PMID:29474172 | |
Biological Process | GO:0031648 | protein destabilization | SIRT6 | IMP | Human | PMID:29474172 | |
Biological Process | GO:0031648 | protein destabilization | Sirt6 | IMP | Mouse | MGI:MGI:4881401|PMID:20141841 | |
Biological Process | GO:1990166 | protein localization to site of double-strand break | SIRT6 | IDA | Human | PMID:27568560 | |
Biological Process | GO:0042752 | regulation of circadian rhythm | Sirt6 | IMP | Mouse | MGI:MGI:6443593|PMID:30782483 | |
Biological Process | GO:0010569 | regulation of double-strand break repair via homologous recombination | SIRT6 | IDA | Human | PMID:19135889 | |
Biological Process | GO:0010569 | regulation of double-strand break repair via homologous recombination | SIRT6 | IDA | Human | PMID:22753495 | |
Biological Process | GO:0050994 | regulation of lipid catabolic process | Sirt6 | IMP | Mouse | MGI:MGI:6357356|PMID:31442424 | |
Biological Process | GO:0019216 | regulation of lipid metabolic process | Sirt6 | IDA | Mouse | MGI:MGI:6429981|PMID:31851938 | |
Biological Process | GO:1903076 | regulation of protein localization to plasma membrane | SIRT6 | IDA | Human | PMID:28406396 | |
Biological Process | GO:0050708 | regulation of protein secretion | SIRT6 | IDA | Human | PMID:23552949 | |
Biological Process | GO:0031667 | response to nutrient levels | Sirt6 | IEP | Rat | PMID:22321393|RGD:9586063 | |
Biological Process | GO:0009411 | response to UV | SIRT6 | IDA | Human | PMID:19109893 | |
Biological Process | GO:0031509 | subtelomeric heterochromatin formation | SIRT6 | IMP | Human | PMID:21847107 |
EXP Inferred from experiment |
IDA Inferred from direct assay |
IEP Inferred from expression pattern |
IGI Inferred from genetic interaction |
IMP Inferred from mutant phenotype |
IPI Inferred from physical interaction |
HTP Inferred from High Throughput Experiment |
HDA Inferred from High Throughput Direct Assay |
HMP Inferred from High Throughput Mutant Phenotype |
HGI Inferred from High Throughput Genetic Interaction |
HEP Inferred from High Throughput Expression Pattern |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 12/17/2024 MGI 6.24 |
![]() |
|