Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SKIL
  • Mouse genes Skil
  • Rat genes Skil
  • Zfish genes skila,skilb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Skil

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Skil	IDA		Mouse	PMID:15657445
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	SKIL	IDA		Human	PMID:10531062
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:Q60974	Human	PMID:10049357
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:Q13485	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:Q9UK41	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:O43482	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:O75716	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:Q08117	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:Q548N1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:Q9H4D5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:Q9Y295	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:Q13485	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:P07196	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:Q53HV7	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:Q9UK41	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:O95995	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:P23025	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:Q05D60	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:O60333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:P07196	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:P08670	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:P13637	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:P16284	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SKIL	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Skil	IPI	UniProtKB:Q96A23	Mouse	MGI:MGI:5294308|PMID:12522145
Molecular Function	GO:0005515	protein binding	Skil	IPI	PR:Q9R1K5	Mouse	PMID:17215516
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SKIL	IDA		Human	PMID:10531062
Cellular Component	GO:0001669	acrosomal vesicle	Skil	IDA		Rat	PMID:19526521|RGD:2308887
Cellular Component	GO:0005634	nucleus	Skil	IDA		Mouse	PMID:18212064
Cellular Component	GO:0005634	nucleus	Skil	IDA		Rat	PMID:19189315|RGD:2308901
Cellular Component	GO:0032991	protein-containing complex	SKIL	IDA		Human	PMID:23610558
Biological Process	GO:0001825	blastocyst formation	Skil	IMP	MGI:MGI:2387096	Mouse	PMID:10811619
Biological Process	GO:0030154	cell differentiation	Skil	IDA		Mouse	PMID:17215516
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	Skil	IMP	MGI:MGI:2387096	Mouse	PMID:10811619
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	Skil	IMP	MGI:MGI:2387096	Mouse	PMID:10811619
Biological Process	GO:0070306	lens fiber cell differentiation	Skil	IDA		Mouse	PMID:17215516
Biological Process	GO:0002260	lymphocyte homeostasis	Skil	IMP	MGI:MGI:2387096	Mouse	PMID:10811619
Biological Process	GO:0045596	negative regulation of cell differentiation	Skil	IDA		Mouse	PMID:17215516
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Skil	IGI	MGI:MGI:98725	Mouse	PMID:18212064
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Skil	IDA		Mouse	PMID:10811619
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Skil	IGI	MGI:MGI:98834	Mouse	PMID:18212064
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Skil	IGI	MGI:MGI:98834	Mouse	PMID:15677329
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	Skil	IMP		Mouse	PMID:15677329
Biological Process	GO:0050772	positive regulation of axonogenesis	Skil	IMP		Rat	PMID:19339625|RGD:2308917
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Skil	IMP	MGI:MGI:2387096	Mouse	PMID:10811619
Biological Process	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage	Skil	IMP	MGI:MGI:2387096	Mouse	PMID:10811619
Biological Process	GO:0051726	regulation of cell cycle	Skil	IMP	MGI:MGI:2387096	Mouse	PMID:10811619
Biological Process	GO:0034097	response to cytokine	Skil	IEP		Rat	PMID:19189315|RGD:2308901
Biological Process	GO:0007283	spermatogenesis	Skil	IEP		Rat	PMID:19526521|RGD:2308887
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Skil	IGI	MGI:MGI:98834	Mouse	PMID:18212064
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Skil	IGI	MGI:MGI:98725	Mouse	PMID:18212064

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern