Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SKOR2
  • Mouse genes Skor2
  • Rat genes Skor2
  • Zfish genes skor2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Skor2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Skor2	IDA		Mouse	PMID:24491816
Molecular Function	GO:0042826	histone deacetylase binding	Skor2	IPI	PR:O09106	Mouse	PMID:21937600
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	SKOR2	IDA		Human	PMID:28473536
Molecular Function	GO:0046332	SMAD binding	SKOR2	IPI	UniProtKB:P84022	Human	PMID:16200078
Molecular Function	GO:0046332	SMAD binding	SKOR2	IPI	UniProtKB:Q15796	Human	PMID:16200078
Molecular Function	GO:0046332	SMAD binding	Skor2	IPI	PR:Q8BUN5	Mouse	PMID:21937600
Molecular Function	GO:0046332	SMAD binding	Skor2	IPI	PR:P70340	Mouse	PMID:21937600
Cellular Component	GO:0005737	cytoplasm	SKOR2	IDA		Human	PMID:16200078
Cellular Component	GO:0005634	nucleus	SKOR2	IDA		Human	PMID:16200078
Cellular Component	GO:0005634	nucleus	Skor2	IDA		Mouse	MGI:MGI:3801345|PMID:18522874
Cellular Component	GO:0005634	nucleus	Skor2	IDA		Mouse	PMID:21937600
Biological Process	GO:0048468	cell development	Skor2	IMP		Mouse	PMID:24491816
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	Skor2	IMP	MGI:MGI:5300464	Mouse	PMID:21937600
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	Skor2	IMP		Mouse	PMID:24491816
Biological Process	GO:0021587	cerebellum morphogenesis	Skor2	IMP	MGI:MGI:5300464	Mouse	PMID:21937600
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	Skor2	IGI	MGI:MGI:88177	Mouse	PMID:21937600
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Skor2	IDA		Mouse	MGI:MGI:3801345|PMID:18522874
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Skor2	IDA		Mouse	PMID:21937600
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	SKOR2	IDA		Human	PMID:16200078
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	Skor2	IMP	MGI:MGI:5300464	Mouse	PMID:21937600
Biological Process	GO:0021936	regulation of cerebellar granule cell precursor proliferation	Skor2	IMP	MGI:MGI:5300464	Mouse	PMID:21937600
Biological Process	GO:0048814	regulation of dendrite morphogenesis	Skor2	IMP	MGI:MGI:5300464	Mouse	PMID:21937600
Biological Process	GO:1902692	regulation of neuroblast proliferation	Skor2	IMP	MGI:MGI:5300464	Mouse	PMID:21937600
Biological Process	GO:0007224	smoothened signaling pathway	Skor2	IMP	MGI:MGI:5300464	Mouse	PMID:21937600

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern