Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLAMF1
  • Mouse genes Slamf1
  • Rat genes Slamf1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slamf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	SLAMF1	IPI	UniProtKB:Q13291	Human	PMID:21217702
Molecular Function	GO:0042802	identical protein binding	SLAMF1	IPI	UniProtKB:Q13291	Human	PMID:21982860
Molecular Function	GO:0042802	identical protein binding	Slamf1	IDA		Mouse	PMID:25799045
Molecular Function	GO:0005515	protein binding	SLAMF1	IPI	UniProtKB:O60880	Human	PMID:10549287
Molecular Function	GO:0005515	protein binding	SLAMF1	IPI	UniProtKB:O60880	Human	PMID:11389028
Molecular Function	GO:0005515	protein binding	SLAMF1	IPI	UniProtKB:O60880	Human	PMID:11477068
Molecular Function	GO:0005515	protein binding	SLAMF1	IPI	UniProtKB:O60880	Human	PMID:11806999
Molecular Function	GO:0005515	protein binding	SLAMF1	IPI	UniProtKB:O60880	Human	PMID:11823424
Molecular Function	GO:0005515	protein binding	SLAMF1	IPI	UniProtKB:O60880	Human	PMID:12225753
Molecular Function	GO:0005515	protein binding	SLAMF1	IPI	UniProtKB:O60880	Human	PMID:12545174
Molecular Function	GO:0005515	protein binding	SLAMF1	IPI	UniProtKB:O60880	Human	PMID:14674764
Molecular Function	GO:0005515	protein binding	SLAMF1	IPI	UniProtKB:O60880-1	Human	PMID:15841490
Molecular Function	GO:0005515	protein binding	SLAMF1	IPI	UniProtKB:O60880-1	Human	PMID:16983070
Molecular Function	GO:0005515	protein binding	SLAMF1	IPI	UniProtKB:O60880	Human	PMID:20231852
Molecular Function	GO:0005515	protein binding	SLAMF1	IPI	UniProtKB:Q92918	Human	PMID:20231852
Molecular Function	GO:0005515	protein binding	SLAMF1	IPI	UniProtKB:Q786F2	Human	PMID:22048310
Molecular Function	GO:0005515	protein binding	SLAMF1	IPI	UniProtKB:O60880	Human	PMID:9774102
Molecular Function	GO:0005515	protein binding	Slamf1	IPI	UniProtKB:O88890|UniProtKB:P39688	Mouse	MGI:MGI:3653974|PMID:16847311
Molecular Function	GO:0005515	protein binding	Slamf1	IPI	UniProtKB:O88890	Mouse	MGI:MGI:3836377|PMID:19151721
Molecular Function	GO:0005515	protein binding	Slamf1	IPI	PR:Q8K245	Mouse	PMID:22493499
Molecular Function	GO:0005515	protein binding	Slamf1	IPI	PR:O35324	Mouse	PMID:16425036
Molecular Function	GO:0005515	protein binding	Slamf1	IPI	PR:Q6PF93	Mouse	PMID:22493499
Molecular Function	GO:0005515	protein binding	Slamf1	IPI	PR:Q45HK4	Mouse	PMID:16425036
Molecular Function	GO:0005515	protein binding	Slamf1	IPI	PR:O88597	Mouse	PMID:22493499
Molecular Function	GO:0005515	protein binding	Slamf1	IPI	PR:O88890	Mouse	PMID:10970095
Molecular Function	GO:0042169	SH2 domain binding	SLAMF1	IDA		Human	PMID:9774102
Molecular Function	GO:0038023	signaling receptor activity	Slamf1	IDA		Mouse	PMID:25799045
Cellular Component	GO:0009986	cell surface	Slamf1	IDA		Mouse	PMID:22960654
Cellular Component	GO:0009897	external side of plasma membrane	Slamf1	IDA		Mouse	PMID:18971422
Cellular Component	GO:0009897	external side of plasma membrane	Slamf1	IDA		Mouse	PMID:20660734
Cellular Component	GO:0009897	external side of plasma membrane	Slamf1	IDA		Mouse	PMID:26095368
Cellular Component	GO:0009897	external side of plasma membrane	Slamf1	IDA		Mouse	PMID:23528453
Cellular Component	GO:0070062	extracellular exosome	SLAMF1	HDA		Human	PMID:20458337
Cellular Component	GO:0045335	phagocytic vesicle	Slamf1	IDA		Mouse	PMID:22493499
Biological Process	GO:0002232	leukocyte chemotaxis involved in inflammatory response	Slamf1	IMP	MGI:MGI:3044919	Mouse	PMID:25799045
Biological Process	GO:0002277	myeloid dendritic cell activation involved in immune response	SLAMF1	IDA		Human	PMID:16317102
Biological Process	GO:0001779	natural killer cell differentiation	Slamf1	IMP		Mouse	MGI:MGI:3763993|PMID:18031695
Biological Process	GO:0001787	natural killer cell proliferation	Slamf1	IMP		Mouse	MGI:MGI:3763993|PMID:18031695
Biological Process	GO:2000349	negative regulation of CD40 signaling pathway	SLAMF1	IDA		Human	PMID:16317102
Biological Process	GO:0032695	negative regulation of interleukin-12 production	SLAMF1	IDA		Human	PMID:16317102
Biological Process	GO:0032715	negative regulation of interleukin-6 production	SLAMF1	IDA		Human	PMID:16317102
Biological Process	GO:0002725	negative regulation of T cell cytokine production	Slamf1	IDA		Mouse	MGI:MGI:5700313|PMID:11477403
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	SLAMF1	IDA		Human	PMID:16317102
Biological Process	GO:0032689	negative regulation of type II interferon production	Slamf1	IDA		Mouse	MGI:MGI:5700313|PMID:11477403
Biological Process	GO:0042104	positive regulation of activated T cell proliferation	Slamf1	IDA		Mouse	MGI:MGI:5700493|PMID:9126961
Biological Process	GO:2000510	positive regulation of dendritic cell chemotaxis	Slamf1	IMP	MGI:MGI:3044919	Mouse	PMID:25799045
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	SLAMF1	IDA		Human	PMID:20231852
Biological Process	GO:0046330	positive regulation of JNK cascade	SLAMF1	IDA		Human	PMID:20231852
Biological Process	GO:0010759	positive regulation of macrophage chemotaxis	Slamf1	IMP	MGI:MGI:3044919	Mouse	PMID:25799045
Biological Process	GO:0010759	positive regulation of macrophage chemotaxis	Slamf1	IMP	MGI:MGI:3044919	Mouse	PMID:22960654
Biological Process	GO:2000556	positive regulation of T-helper 1 cell cytokine production	Slamf1	IDA		Mouse	MGI:MGI:5700493|PMID:9126961
Biological Process	GO:0032729	positive regulation of type II interferon production	Slamf1	IDA		Mouse	MGI:MGI:5700493|PMID:9126961
Biological Process	GO:0050790	regulation of catalytic activity	Slamf1	IMP	MGI:MGI:3044919	Mouse	PMID:22493499
Biological Process	GO:0031338	regulation of vesicle fusion	Slamf1	IMP	MGI:MGI:3044919	Mouse	PMID:22493499
Biological Process	GO:0031338	regulation of vesicle fusion	Slamf1	IMP		Mouse	PMID:22493499

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern