Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLAMF8
  • Mouse genes Slamf8
  • Rat genes Slamf8
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slamf8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Slamf8	IDA		Mouse	PMID:25799045
Molecular Function	GO:0005515	protein binding	SLAMF8	IPI	UniProtKB:P54852	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLAMF8	IPI	UniProtKB:Q9NZG7	Human	PMID:32296183
Molecular Function	GO:0038023	signaling receptor activity	Slamf8	IDA		Mouse	PMID:25799045
Biological Process	GO:0002336	B-1 B cell lineage commitment	Slamf8	IDA		Mouse	MGI:MGI:6215454|PMID:11313408
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Slamf8	IMP	MGI:MGI:5442794	Mouse	PMID:22593622
Biological Process	GO:0042742	defense response to bacterium	Slamf8	IMP	MGI:MGI:5442794	Mouse	PMID:22593622
Biological Process	GO:0002232	leukocyte chemotaxis involved in inflammatory response	Slamf8	IMP	MGI:MGI:5442794	Mouse	PMID:25799045
Biological Process	GO:2000509	negative regulation of dendritic cell chemotaxis	Slamf8	IMP	MGI:MGI:5442794	Mouse	PMID:25799045
Biological Process	GO:0010760	negative regulation of macrophage chemotaxis	Slamf8	IMP	MGI:MGI:5442794	Mouse	PMID:25799045
Biological Process	GO:0090027	negative regulation of monocyte chemotaxis	Slamf8	IMP	MGI:MGI:5442794	Mouse	PMID:25799045
Biological Process	GO:1902623	negative regulation of neutrophil migration	Slamf8	IMP	MGI:MGI:5442794	Mouse	PMID:25799045
Biological Process	GO:0060266	negative regulation of respiratory burst involved in inflammatory response	Slamf8	IMP	MGI:MGI:5442794	Mouse	PMID:25799045
Biological Process	GO:0090383	phagosome acidification	Slamf8	IMP	MGI:MGI:5442794	Mouse	PMID:22593622
Biological Process	GO:0045577	regulation of B cell differentiation	Slamf8	IDA		Mouse	MGI:MGI:6215454|PMID:11313408
Biological Process	GO:0043549	regulation of kinase activity	Slamf8	IMP	MGI:MGI:5442794	Mouse	PMID:22593622
Biological Process	GO:0033860	regulation of NAD(P)H oxidase activity	Slamf8	IMP	MGI:MGI:5442794	Mouse	PMID:22593622

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern