Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC15A1
  • Mouse genes Slc15a1
  • Rat genes Slc15a1
  • Zfish genes slc15a1a,slc15a1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc15a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016248	channel inhibitor activity	Slc15a1	IDA		Rat	PMID:15684415|RGD:2302143
Molecular Function	GO:0071916	dipeptide transmembrane transporter activity	SLC15A1	IDA		Human	PMID:18367661
Molecular Function	GO:0071916	dipeptide transmembrane transporter activity	SLC15A1	IDA		Human	PMID:19685173
Molecular Function	GO:0071916	dipeptide transmembrane transporter activity	SLC15A1	IDA		Human	PMID:8914574
Molecular Function	GO:0071916	dipeptide transmembrane transporter activity	SLC15A1	IDA		Human	PMID:9835627
Molecular Function	GO:0071916	dipeptide transmembrane transporter activity	Slc15a1	IDA		Mouse	MGI:MGI:6450380|PMID:26320580
Molecular Function	GO:0015175	neutral L-amino acid transmembrane transporter activity	slc15a1b	IDA		Zfish	PMID:20953145
Molecular Function	GO:0015333	peptide:proton symporter activity	SLC15A1	IDA		Human	PMID:18367661
Molecular Function	GO:0015333	peptide:proton symporter activity	SLC15A1	IDA		Human	PMID:19685173
Molecular Function	GO:0015333	peptide:proton symporter activity	SLC15A1	IDA		Human	PMID:7896779
Molecular Function	GO:0015333	peptide:proton symporter activity	SLC15A1	IDA		Human	PMID:8914574
Molecular Function	GO:0015333	peptide:proton symporter activity	SLC15A1	IDA		Human	PMID:9835627
Molecular Function	GO:0015333	peptide:proton symporter activity	Slc15a1	IDA		Mouse	MGI:MGI:6450380|PMID:26320580
Molecular Function	GO:0005427	proton-dependent oligopeptide secondary active transmembrane transporter activity	Slc15a1	IDA		Mouse	PMID:11004485
Molecular Function	GO:0042937	tripeptide transmembrane transporter activity	SLC15A1	IDA		Human	PMID:9835627
Cellular Component	GO:0016324	apical plasma membrane	SLC15A1	IDA		Human	PMID:28408210
Cellular Component	GO:0016324	apical plasma membrane	Slc15a1	IDA		Rat	PMID:12023509|RGD:729764
Cellular Component	GO:0005903	brush border	Slc15a1	IDA		Mouse	MGI:MGI:5621262|PMID:22114352
Cellular Component	GO:0016020	membrane	Slc15a1	IDA		Mouse	PMID:11004485
Cellular Component	GO:0016020	membrane	Slc15a1	IDA		Rat	PMID:15684415|RGD:2302143
Cellular Component	GO:0005886	plasma membrane	SLC15A1	IDA		Human	PMID:23137377
Biological Process	GO:0003333	amino acid transmembrane transport	slc15a1b	IDA		Zfish	PMID:20953145|ZFIN:ZDB-PUB-101027-11
Biological Process	GO:0140206	dipeptide import across plasma membrane	SLC15A1	IDA		Human	PMID:18367661
Biological Process	GO:0140206	dipeptide import across plasma membrane	SLC15A1	IDA		Human	PMID:19685173
Biological Process	GO:0140206	dipeptide import across plasma membrane	Slc15a1	IDA		Mouse	MGI:MGI:6450380|PMID:26320580
Biological Process	GO:0072237	metanephric proximal tubule development	Slc15a1	IEP		Rat	PMID:30645697|RGD:155631307
Biological Process	GO:0051956	negative regulation of amino acid transport	Slc15a1	IDA		Rat	PMID:15684415|RGD:2302143
Biological Process	GO:0015804	neutral amino acid transport	slc15a1b	IDA		Zfish	PMID:20953145|ZFIN:ZDB-PUB-101027-11
Biological Process	GO:0035672	oligopeptide transmembrane transport	Slc15a1	IDA		Mouse	MGI:MGI:1860310|PMID:11004485
Biological Process	GO:0006857	oligopeptide transport	Slc15a1	IDA		Mouse	PMID:11004485
Biological Process	GO:0015833	peptide transport	slc15a1b	IDA		Zfish	PMID:31890051
Biological Process	GO:0015833	peptide transport	slc15a1a	IDA		Zfish	PMID:31890051

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern